Keywords: MN، micronucleus; ANOVA, analysis of variance; D. magna, Daphnia magna; EC50, half maximal effective concentration; LC50, lethal concentration 50%; MN, micronucleus; ROS, reactive oxygen speciesZooplankton; Daphnia magna; Micronucleus assay; Metals; Deltamethrin
مقالات ISI MN، micronucleus (ترجمه نشده)
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Keywords: MN، micronucleus; MN, micronucleus; MNi, micronuclei; K−MN, kinetochore-negative micronucleus; K+MN, Kinetochore-positive micronucleus; DC, displaced chromosome; K−DC, kinetochore-negative displaced chromosome; K+DC, kinetochore-positive displaced chromosome; LC, lagging c
Keywords: MN، micronucleus; CAs, chromosomal aberrations; MN, micronucleus; SLT, smokeless tobacco; BQ, betel quid; TL, tail length; TM, tail momentTobacco; Buccal cells; Micronuclei; Cytogenetics; Smokers and smokeless tobacco
Keywords: MN، micronucleus; %TDNA, percentage of DNA in the comet tail; BNMN, binucleated micronucleated cells; CBPI, cytokinesis-block proliferation index; CI, confidence interval; IARC, International Agency for Research on Cancer; MN, micronucleus; MNcyt, MN frequency evaluated by
Keywords: MN، micronucleus; A, amorphous; B, banana shaped; BSA, bovine serum albumin; CMC, carboxymethyl cellulose; CP, cyclophosphamide; DH, double headed; DT, double tailed; F, folded; H, hookless; MN, micronucleus; MNNCE, micronucleus in normochromatic erythrocytes; MNPCE, micro
Toxic and genotoxic effects of the imazethapyr-based herbicide formulation Pivot H® on montevideo tree frog Hypsiboas pulchellus tadpoles (Anura, Hylidae)
Keywords: MN، micronucleus; BL, blebbed nucleus; BN, binucleated erythrocyte; CP, cyclophosphamide; GDI, genetic damage index; GS, Gosner stage; IM, immobility; IMZT, imazethapyr; IS, irregular swimming; LB, lobed nucleus; MN, micronucleus; NT, notched nucleus; SCGE, single-cell gel
The genotoxic effects of the imidacloprid-based insecticide formulation Glacoxan Imida on Montevideo tree frog Hypsiboas pulchellus tadpoles (Anura, Hylidae)
Keywords: MN، micronucleus; BL, blebbed nuclei; BN, binucleated erythrocyte; CP, cyclophosphamide; GDI, genetic damage index; IMI, imidacloprid; LB, lobed nuclei; MN, micronucleus; NT, notched nuclei; SCGE, single-cell gel electrophoresisAcute toxicity; Amphibian tadpoles; Comet ass
Sex-specific dose-response analysis of genotoxicity in cyproterone acetate-treated F344 rats
Keywords: MN، micronucleus; CPA, cyproterone acetate; COC, combined oral contraceptive; VTE, venous thromboembolism; hOGG1, human 8-oxoguanine DNA N-glycosylase 1; EndoIII, endonuclease-III; ROS, reactive oxygen species; LOEL, lowest observable effect level; MN, micronucleus; bw, by
Single cell gel electrophoresis (SCGE) and Pig-a mutation assay in vivo-tools for genotoxicity testing from a regulatory perspective: A study of benzo[a]pyrene in Ogg1−/− mice
Keywords: MN، micronucleus; Fpg, formamidopyrimidine DNA glycosylase; OECD, Organisation for Economic Co-operation and Development; TG, test guideline; MN, micronucleus; ENU, N-ethyl-N-nitrosourea; RBC, red blood cells; RET, reticulocytes; NER, nucleotide excision repair; Ogg1, 8-ox
Comet assay in gill cells of Prochilodus lineatus exposed in vivo to cypermethrin
Keywords: MN، micronucleus; BV, basal values; CA, comet assay; CYP, cypermethrin; DI, damage index; EB, ethidium bromide; EGC, epithelial gill cells; LMPA, low melting point agarose; MN, micronucleus; MMS, methyl methanesulfonate; NC, negative control; NMPA, normal melting point aga
Insulin mediated DNA damage in mammalian colon cells and human lymphocytes in vitro
Keywords: MN، micronucleus; Lectin/PHA L8902, phytohaemagglutinin; H2DCF-DA, 2′,7′-dichlorodihydrofluorescein diacetate; DHE, dihydroethidium; FPG, formamidopyrimidine-DNA glycosylase; MN, micronucleus; Mn-cells, cells with one or more micronucleus(i); NM, normal medium; PBS, phosph
Cytotoxic and genotoxic effects of acitretin, alone or in combination with psoralen–ultraviolet A or narrow-band ultraviolet B-therapy in psoriatic patients
Keywords: MN، micronucleus; BN, bi-nucleated cells; CBMN, cytokinesis blocked micronucleus; CBPI, cytokinesis-blocked proliferation index; EDTA, ethylenediaminetetraacetic acid; FBS, fetal bovine serum; MN, micronucleus; NBUV, Bnarrow-band ultraviolet B; PASI, psoriasis area and sev
Evaluation of the cytotoxicity, genotoxicity and apoptotic induction of an aqueous extract of Achyrocline satureioides (Lam.) DC
Keywords: MN، micronucleus; Achyrocline satureioides (Lam.) DC; Asteraceae; Cold aqueous extract; Cytotoxicity; Genotoxicity; ApoptosisCA, comet assay; CAE, cold aqueous exctract; FCS, fetal calf serum; ME, mercaptoethanol; MN, micronucleus; MNPCE, micronucleated polychromatic eryth
Pretreatment with valproic acid, a histone deacetylase inhibitor, enhances the sensitivity of the peripheral blood micronucleus assay in rodents
Keywords: MN، micronucleus; ALC, alcohol; AZT, zidovudine; CP, cyclophosphamide; ERT, erythrocytes; HDAC, histone deacetylase; MN, micronucleus; MNERT, micronucleated erythrocytes; MNRET, micronucleated reticulocytes; MTX, methotrexate; PB, peripheral blood; PBMN, peripheral blood m
Dysfunctions of the translational machinery in digestive glands of mussels exposed to mercury ions
Keywords: MN، micronucleus; AAS, atomic absorption spectophotometry; AcPhe-tRNA, acetylphenylalanyl-tRNA; LP, labilization period; MDA, malondialdehyde; MTs, metallothioneins; MN, micronucleus; ROS, reactive oxygen species; TBARS, thiobarbituric reactive species; SOD, superoxide dis
Combination effects of chronic cadmium exposure and gamma-irradiation on the genotoxicity and cytotoxicity of peripheral blood lymphocytes and bone marrow cells in rats
Keywords: MN، micronucleus; Cd, cadmium; LD, low dose; HD, high dose; MT, metallothionein; CFU-GM, colony forming unit-granulocyte and macrophage; PCE, polychromatic erythrocytes; NCE, normochromatic erythrocyte; MN, micronucleus; hprt, hypoxanthine–guanine phosphoribosyl transferas
The prostate cancer risk locus at 10q11 is associated with DNA repair capacity
Keywords: MN، micronucleus; Prostate cancer; Micronucleus assay; Mitotic delay; rs10993994; MSMB; PARGADP, adenosine diphoshate; BNC, binucleated cells; GWAS, genome-wide association study; LD, linkage disequilibrium; MD, mitotic delay; MDI, mitotic delay index; MN, micronucleus; MS
An ethanolic extract of black cohosh causes hematological changes but not estrogenic effects in female rodents
Keywords: MN، micronucleus; BCE, black cohosh extract; PND, postnatal day; MN, micronucleus; RET, reticulocytes; MN-RET, micronucleated reticulocytes; MNE, micronucleated erythrocytes; SEM, standard error of the meanBlack cohosh; Actaea racemosa; Non-regenerative macrocytic anemia;
Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity
Keywords: MN، micronucleus; HC, homocysteine; MN, micronucleus; MNed, micronucleated; RDI, recommended dietary intake; mtDNA, mitochondrial DNA; SSB, single-stranded break; DSB, double-stranded break; RBCs, red blood cellsGenome; Integrity; Chromosome aberrations; Micronuclei; DNA m
The HUman MicroNucleus project on eXfoLiated buccal cells (HUMNXL): The role of life-style, host factors, occupational exposures, health status, and assay protocol
Keywords: MN، micronucleus; BMCyt, Buccal Micronucleus Cytome Assay; CI, Confidence interval; FFG, Feulgen-Fast Green; FR, Frequency Ratio; HUMN, the HUman MicroNucleus project; HUMNXL, the HUman MicroNucleus project on exfoliated buccal cells; MN, Micronucleus; MNed, Micronucleated
Comparison of different cytotoxicity measures for the in vitro micronucleus test (MNVit) in L5178Y tk+/− cells: Summary of 4 compounds (Mitomycin C, Cyclophosphamide, Colchicine and Diethylstilboestrol) with clastogenic and aneugenic mode of action
Keywords: MN، micronucleus; MN, micronucleus; RCC, relative cell count; RICC, relative increase in cell counts; RPD, relative population doubling; DES, Diethylstilboestrol; COL, Colchicine; MMC, Mitomycin C; CP, CyclophosphamideIn vitro micronucleus test; Cytotoxicity; L5178Y tk+/−
Formaldehyde-induced chromosomal aberrations and apoptosis in peripheral blood lymphocytes of personnel working in pathology departments
Keywords: MN، micronucleus; BrdU, 5-bromo-2′-deoxyuridine; CA, chromosome aberrations; FA, formaldehyde; HF/SCE, high frequency SCE cells; HPRT, hypoxanthine-guanine phosphoribosyl transferase; LI, labeling index; MN, micronucleus; PBL, peripheral blood lymphocyte; PCD, premature ce
Live cell imaging of micronucleus formation and development
Keywords: MN، micronucleus; MN, micronucleus; MNi, micronuclei; MMC, mitomycin C; VC, vincristine; GFP, green fluorescent protein; CFP, cyan fluorescent proteinMicronucleus test; Micronuclei; Chromosome aberration; Aneuploid; M-phase
Cooperative biological effects between ionizing radiation and other physical and chemical agents
Keywords: MN، micronucleus; BER, base excision repair; DSB, double-strand break; ELF EMFs, extremely low-frequency electromagnetic fields; IR, ionizing radiation; MN, micronucleus; NER, nucleotide excision repair; SAR, specific absorption rateCombined exposure; Ionizing radiation; E
Micronucleus and comet assay in the peripheral blood of juvenile rat: Establishment of assay feasibility, time of sampling and the induction of DNA damage
Keywords: MN، micronucleus; CIS, cisplatin; CBL, chlorambucil; CP, cyclophosphamide; ERTs, erythrocytes; MTX, methotrexate; MN, micronucleus; MNERTs, micronucleated erythrocytes; MNRETs, micronucleated reticulocytes; PACLI, paclitaxel; PBE, peripheral blood erythrocytes; PBMN, perip
An in vitro micronucleus assay with size-classified micronucleus counting to discriminate aneugens from clastogens
Keywords: MN، micronucleus; CHL, Chinese hamster lung; +CEN, Centromere-positive; −CEN, centromere negative; DMSO, dimethyl sulfoxide; DAPI, 4′,6-diamidino-2-phenylindole; FISH, fluorescence in situ hybridization; M, mitotic; MN, micronucleus; MEM, minimum essential medium; MMC, mit
Evaluation of different cytotoxic and cytostatic measures for the in vitro micronucleus test (MNVit): Summary of results in the collaborative trial
Keywords: MN، micronucleus; MN, micronucleus; RCC, relative cell count; RICC, relative increase in cell counts; RPD, relative population doubling; RI, eplicative index; CBPI, cytokinesis block proliferation index; 2-AA, 2-aminoanthracene; 5-FU, 5-fluorouracilIn vitro micronucleus te
Evaluation of multi-organ DNA damage by comet assay from 28 days repeated dose oral toxicity test in mice: A practical approach for test integration in regulatory toxicity testing
Keywords: MN، micronucleus; MTX, methotrexate; MN, micronucleus; IWGTP, International Workshop on Genotoxicity Test Procedures; REACH, Registration Evaluation Authorization Restriction of Chemicals; MDA, malondialdehyde; GSH, glutathione; RETs, reticulocytes; NCEs, normochromatic er
Different genotoxic profiles between depleted and enriched uranium
Keywords: MN، micronucleus; MN, micronucleus; BN-1MN, binucleated cell with one micronucleus; BN-1MNC+, binucleated cell with one centromere-positive micronucleus; BN-1MNC−, binucleated cell with one centromere-negative micronucleus; Mono-MNx, mononucleated cells with micronuclei; B
Enhanced radiation damage in irradiated and non-irradiated bystander regions by co-exposure to myosmine
Keywords: MN، micronucleus; MN, micronucleus; DSB, DNA double-strand break; LET, linear energy transfer; HPB, 4-hydroxy-1-(3-pyridyl)-1-butanone; keto acid, 4-oxo-4-(3-pyridyl)butanoic acid; RIBE, radiation-induced bystander effects; γ-H2AX, phosphorylated form of H2AX protein; c-PT
Inhibition of acrylamide genotoxicity in human liver-derived HepG2 cells by the antioxidant hydroxytyrosol
Keywords: MN، micronucleus; DCFH-DA, dichlorofluorescein diacetate; MN, micronucleus; HT, hydroxytyrosol; ROS, reactive oxygen species; GSH, glutathione; t-BHP, tert-butylhydroperoxide; MEM, minimum essential Eagle's medium; AA, acrylamide; PBN, N-tert-butyl-alpha-phenylnitrone; GA,
Signaling factors for irradiated glioma cells induced bystander responses in fibroblasts
Keywords: MN، micronucleus; MN, micronucleus; TGF-β1, transforming growth factor-β1; AG, aminoguanidine; DEANO, diethylamine nitric oxide; NO, nitric oxide; iNOS, inducible NO synthase; ROS, reactive oxygen species; CM, conditioned medium; RIBE, radiation-induced bystander effectMic
Multiple origins of spontaneously arising micronuclei in HeLa cells: Direct evidence from long-term live cell imaging
Keywords: MN، micronucleus; MN, micronucleus; MNi, micronuclei; DC, displaced chromosome; LC, lagging chromosome; CB, chromosome bridgeMicronuclei; Micronucleus origin; Live cell imaging; Displaced chromosome; Lagging chromosome; Chromosome bridge
Genotoxicity studies on green tea catechin
Keywords: MN، micronucleus; PE, plating efficiency; RS, relative survival; RSG, relative survival growth; RTG, relative total growth; MF, mutation frequency; L-MF, MF of large colonies; S-MF, MF of small colonies; T-MF, MF of total colonies; MN, micronucleus; NCE, normochromatic ery
Genotoxic effect and nitrative DNA damage in HepG2 cells exposed to aristolochic acid
Keywords: MN، micronucleus; AA, aristolochic acid; MN, micronucleus; RNS, reactive nitrogen species; NO, nitric oxide; 8-OHdG, 8-hydroxydeoxyguanosine; DAN, 2,3-diaminonaphthalene; EtBr, ethidium bromide; BNC, binucleated cellsAristolochic acid; Genotoxicity; Nitric oxide; HepG2 cel
Sulforaphane as a promising molecule for fighting cancer
Keywords: MN، micronucleus; CYP, cytochrome P450; GLS, glucosinolates; GST, glutathione S transferase; HDAC, histone deacetylase; ITCs, isothiocyanates; MN, micronucleus; NQO1, NAD(P)H:quinone oxidoreductase 1; PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; SFN, sulforaphane
Trimethylantimony dichloride causes genotoxic effects in Chinese hamster ovary cells after forced uptake
Keywords: MN، micronucleus; Trimethylantimony dichloride; Uptake; Cytotoxicity; Micronuclei; Chromosome aberrations; SCETMSb, trimethylantimony dichloride; MN, micronucleus; CA, chromosome aberration; SCE, sister chromatid exchange; CHO-9, Chinese hamster ovary cells; PBS, phosphate
Cytokinesis-block micronucleus assay evolves into a “cytome” assay of chromosomal instability, mitotic dysfunction and cell death
Keywords: MN، micronucleus; BFB cycle, breakage–fusion–bridge cycle; BN, binucleated; CBMN assay, cytokinesis-block micronucleus assay; MN, micronucleus; MNi, micronuclei; MNed, micronucleated; NBUDs, nuclear buds; NPBs, nucleoplasmic bridgesCytokinesis-block; Cytome; Chromosomal in
Genotoxic risk assessment of pathology and anatomy laboratory workers exposed to formaldehyde by use of personal air sampling and analysis of DNA damage in peripheral lymphocytes
Keywords: MN، micronucleus; DPC, DNA-protein cross-links; MN, micronucleus; CBMN, cytokinesis-blocked micronucleus; 3D, damaged DNA detection; FISH, fluorescent in situ hybridization; C − MN, micronucleus without a centromere; C + MN, micronucleus containing one or several centromer