دانلود مقالات ISI درباره Moe, Molecular Operating Environment + ترجمه فارسی

NQO1 rs1800566 polymorph is more prone to NOx induced lung injury: Endorsing deleterious functionality through informatics approach

Keywords: WT, Wild type; NQO1, NAD(P)H:quinone oxidoreductase 1; RMSD, Root mean square deviation; CUPSAT, Cologne University Protein Stability Analysis Tool; ΔΔG, unfolding energy; PDB, Protein data bank; MOE, Molecular Operating Environment; NPA, Nosé-Poincaré-An

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals

Keywords: MOE, Molecular Operating Environment; MW, microwave; TbrPDEB1, Trypanosoma brucei phosphodiesterase B1; TbrPDEB2, Trypanosoma brucei phosphodiesterase B2Pyridazinone; Phosphodiesterase; Trypanosome brucei; African trypanosomiasis; TbrPDEB1; Human PDEs

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Antipsychotics inhibit glucose transport: Determination of olanzapine binding site in Staphylococcus epidermidis glucose/H+ symporter

Keywords: GLUT, glucose transporter (SLC2); GlcPSe, Staphylococcus epidermidis glucose/H+ symporter; MOE, Molecular Operating Environment; RSO vesicles, right-side-out vesicles; E. coli, Escherichia coli; KPi, potassium phosphate buffer; DTT, dithiothreitol; EDTA,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

In silico identification of novel IL-1β inhibitors to target protein–protein interfaces

Keywords: CADD, computer aided drug design; FRED, fast rigid exhaustive docking; IL-1β, interleukin-1 beta; IL-1R, interleukin-1 receptor; MOE, molecular operating environment; PDB, protein data bank; PLIF, protein ligand interaction fingerprints; QSAR, quantitativ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of piperazine derivatives as a novel class of γ-secretase modulators that selectively lower Aβ42 production

Keywords: OHOBSERAKPOKBC-INIZCTEOSA-NGSM, γ-secretase modulator; AD, Alzheimer’s disease; Aβ, amyloid beta; APP, amyloid precursor protein; NSAID, nonsteroidal anti-inflammatory drug; IP, inflection point; MOE, Molecular Operating Environment; MLM, mice liver micro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Agitation-induced aggregation and subvisible particulate formation in model proteins

Keywords: SEC, size exclusion chromatography; DLS, dynamic light scattering; MOE, Molecular Operating Environment; MFI, Micro-Flow Imaging; CC15, COUNT-CAL 15 micron; HSA, human serum albumin; HEWL, hen egg white lysozyme; IgG2, immunoglobulin type 2; DSF, differen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Consensus in silico computational modelling of the p22phox subunit of the NADPH oxidase

Keywords: Homology Modelling; p22phox; NADPH Oxidase3D, three-dimensional; a.a., amino acids; AMBER, assisted model building with energy refinement; CGD, chronic granulomatous disease; EBI, European Bioinformatics Institute; MOE, molecular operating environment; NA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Homology modeling and structural analysis of 11β-hydroxysteroid dehydrogenase type 2

Keywords: 11βHSD2; Anticancer drug; Homology modeling; Molecular Operating Environment (MOE); Tumor11βHSD, 11β-hydroxysteroid dehydrogenase; LBS, ligand-binding site; MEP, molecular electrostatic potential; MOE, Molecular Operating Environment; SDR, short-chain deh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation

Keywords: Cancer; DNA methyltransferases; Docking; Drug discovery; Epigenetics; Structure–activity relationshipsDNMT, DNA methyltransferase; EGCG, (−)-epigallocatechin-3-gallate; HTVS, high-throughput virtual screening; moe, Molecular Operating Environment; NCI, Na

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular dynamics simulation study on the structural stabilities of polyglutamine peptides

Keywords: polyQ, polyglutamine; MD, molecular dynamics; MOE, Molecular Operating Environment; PBC, periodic boundary condition; RMSD, root mean square deviationPolyglutamine; Huntington's disease; Protein aggregation; β-Helix; Molecular dynamics

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

QSAR analysis of meclofenamic acid analogues as selective COX-2 inhibitors

Keywords: COX-1, Cyclooxygenase-1; COX-2, Cyclooxygenase-2; MOE, molecular operating environment; QSAR, quantitative structure–activity relationshipCOX-1/COX-2/MOE/QSAR/meclofenamic acid analogues

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه