Structural insights into semaphorins and their receptors
Keywords: مکانیزم مولکولی; Crystal structure; Molecular mechanism; Cell surface receptor; Protein interactions
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Up-regulation of the canonical Wnt-3A and Sonic hedgehog signaling underlies melanocortin-induced neurogenesis after cerebral ischemia
Keywords: مکانیزم مولکولی; Cerebral ischemia; Melanocortin MC4 receptor; Neurogenesis; Molecular mechanism; Signaling pathway; Wnt-3A; Sonic hedgehog; Repair factor
Black tea in chemo-prevention of cancer and other human diseases
Keywords: مکانیزم مولکولی; Black tea; Theaflavins; Catechins; Human disease; Molecular mechanism; Cancer
Biokinematic protein simulation by an adaptive dihedral angle approach
Keywords: مکانیزم مولکولی; Protein chain; Serial robot; Biokinematics; Molecular mechanism; Folding
The molecular mechanism of mediation of adsorbed serum proteins to endothelial cells adhesion and growth on biomaterials
Keywords: مکانیزم مولکولی; Biomaterial surface; Protein adsorption and cell adhesion; Molecular mechanism; Proteomics and bioinformatics; Verification experiment
Exploring the molecular mechanism of karrikins and strigolactones
Keywords: مکانیزم مولکولی; Karrikinolide; Strigolactones; Plant hormones; Smoke; Molecular mechanism
Molecular mechanisms underlying the function diversity of transcriptional factor IclR family
Keywords: مکانیزم مولکولی; Mycobacterium tuberculosis; The IclR family; Function; Molecular mechanism;
Physiology of the salivary glands
Keywords: مکانیزم مولکولی; Defence; electrolyte; molecular mechanism; protein; regulation; saliva; salivary gland; secretion; water transport
Molecular origin of the sawtooth behavior and the toughness of nacre
Keywords: مکانیزم مولکولی; Nacre; Sawtooth behavior; Steered molecular dynamics; Molecular mechanism
The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli
Keywords: مکانیزم مولکولی; Gold nanoparticle; Molecular mechanism; Transcriptomic/proteomic analysis; ROS
Evolutionary analysis of prokaryotic heat-shock transcription regulatory protein σ32
Keywords: مکانیزم مولکولی; HSP, heat-shock protein; MSA, multiple sequence alignment; Pfam, protein family; CF, Chou Fasman; GOR, Garnier Osguthorpe RobsonEvolutionary analysis; σ32; Region 2; Region 4; Molecular mechanism
A comprehensive structure–function analysis shed a new light on molecular mechanism by which a novel smart copolymer, NY-3-1, assists protein refolding
Keywords: مکانیزم مولکولی; P(MAc-AA)s; Lysozyme; Protein refolding; Molecular mechanism
Nociceptive stimuli enhance anesthetic-induced neuroapoptosis in the rat developing brain
Keywords: مکانیزم مولکولی; Neonates; Anesthesia; Pain; Neuronal apoptosis; Cognition; Molecular mechanism
A DFT study of the role of Lewis acid catalysts in the mechanism of the 1,3-dipolar cycloaddition of nitrile imines towards electron-deficient acryloyl derivatives
Keywords: مکانیزم مولکولی; 1,3-Dipolar cycloadditions; Nitrile imines; Magnesium Lewis acid; Molecular mechanism; Density functional theory;
Metabonomic study on the cumulative cardiotoxicity of a pirarubicin liposome powder
Keywords: مکانیزم مولکولی; Pirarubicin liposome powders; Cumulative cardiotoxicity; Molecular mechanism; Metabonomics; In vitro cytotoxicity;
Atomistic models of ion and solute transport by the sodium-dependent secondary active transporters
Keywords: مکانیزم مولکولی; Secondary transporter; Molecular mechanism; Substrate specificity; Ion selectivity; Water permeation;
β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo
Keywords: مکانیزم مولکولی; Signal transduction; Transcription; Cloning; Molecular mechanism; Adrenergic stimulation; Heart failure;
Strigolactone analogues and mimics derived from phthalimide, saccharine, p-tolylmalondialdehyde, benzoic and salicylic acid as scaffolds
Keywords: مکانیزم مولکولی; Strigolactone; Parasitic weeds; Bioassay; Striga; Orobanche; Germination; Molecular mechanism; Alternative mode of action; New type stimulants;
Molecular mechanism of vasorelaxant and antiatherogenic effects of the statins in the human saphenous vein graft
Keywords: مکانیزم مولکولی; Statin; Molecular mechanism; Human saphenous vein graft; Coronary artery bypass surgery
Adenosine receptors and cancer
Keywords: مکانیزم مولکولی; A1 adenosine receptor; A2A adenosine receptor; A2B adenosine receptor; A3 adenosine receptor; Cancer; Molecular mechanism
The molecular mechanism of mammalian NO-synthases: A story of electrons and protons
Keywords: مکانیزم مولکولی; Nitric oxide synthase; Molecular mechanism; Electron transfer; Proton transfer; Oxygen; Activation;
Reactivity at (nano)particle-water interfaces, redox processes, and arsenic transport in the environment
Keywords: مکانیزم مولکولی; Arsenic; Aquifers; Bioavailability; Water treatment; Speciation; Adsorption; Experimental artifacts; Molecular mechanism; XAFS spectroscopy; Molecular dynamicsArsenic; Aquifères; Biodisponibilité; Traitement de l’eau; Spéciation; Adsorption; Artéfacts exp
Happy birthday cell penetrating peptides: Already 20 years
Keywords: مکانیزم مولکولی; Cell-penetrating peptide; Non-covalent delivery system; Drug delivery; Molecular mechanism; Therapeutics; Molecular modeling; Structural polymorphism
A DFT study of the role of the Mg complex formation on the mechanism of the 1,3-dipolar cycloadditions of benzonitrile oxides with acryloylpyrazolidinone
Keywords: مکانیزم مولکولی; 1,3-Dipolar cycloadditions; Benzonitrile oxides; Magnesium Lewis acid; Molecular mechanism; Density functional theory;
Molecular mechanism of polyethylene glycol mediated stabilization of protein
Keywords: مکانیزم مولکولی; Molecular mechanism; BSA; Polyethylene glycol; Protein stability
Probing the molecular mechanism of C.I. Acid red 73 binding to human serum albumin
Keywords: مکانیزم مولکولی; C.I. Acid red 73; Human serum albumin (HSA); Molecular mechanism; Spectroscopy; Molecular docking
Molecular mechanisms of congenital heart disease
Keywords: مکانیزم مولکولی; Congenital heart disease; Molecular mechanism; Genetics
The promotion of human malignant melanoma growth by mesoporous silica nanoparticles through decreased reactive oxygen species
Keywords: مکانیزم مولکولی; Mesoporous silica nanoparticles; Promotion tumor growth; Reactive oxygen species; Molecular mechanism
Vitamin D and aging
Keywords: مکانیزم مولکولی; Aging; Cancer; Vitamin D; FGF-23; Molecular mechanism
Titin-induced force enhancement and force depression: A ‘sticky-spring’ mechanism in muscle contractions?
Keywords: مکانیزم مولکولی; Molecular mechanism; Model; Stretch; Shortening; Sarcomere; Myofilament interaction
Theoretical study of the mechanism and regioselectivity of the 1,3-dipolar cycloaddition of diazomethane with methyl acrylate using theoretical approaches
Keywords: مکانیزم مولکولی; 1,3-dipolar cycloadditions; Diazoalkane; Molecular mechanism; Regioselectivity; Reactivity indexes;
Mechanism of sulfite cytotoxicity in isolated rat hepatocytes
Keywords: مکانیزم مولکولی; Cyanide; Cytotoxicity; Free radical; Hepatocytes; Molecular mechanism; Sulfite; Sulfite oxidase
Molecular and cellular mechanisms in the viral exacerbation of asthma
Keywords: مکانیزم مولکولی; Asthma; Pulmonary inflammation; Viral aetiology; Molecular mechanism; Cellular mechanism
Cytotoxicities and induction of metallothionein (MT) and metal regulatory element (MRE)-binding transcription factor-1 (MTF-1) messenger RNA levels in the zebrafish (Danio rerio) ZFL and SJD cell lines after exposure to various metal ions
Keywords: مکانیزم مولکولی; LC50 values of metal ions; Real-time PCR; Gene expression; Molecular mechanism; In vitro toxicity
The aging kidney
Keywords: مکانیزم مولکولی; senescence; pathology; kidney transplantation; oxidative stress; molecular mechanism; pathophysiology
Analyzing Ru(III)–dmso and Ru(III)–dms motifs in compounds used in the synthesis of the antimetastatic agents
Keywords: مکانیزم مولکولی; Ruthenium; X-ray diffraction; Resonance spectroscopy; Antitumor research; Molecular mechanism
Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis
Keywords: مکانیزم مولکولی; Flavones; Flavonols; Apoptosis; Cell cycle arrest; Molecular mechanism; CytotoxicityBAX, BCL2-associated X protein; BTG2, BTG family member 2; DMSO, dimethyl sulfoxide; EB, ethidium bromide; EDTA, ethylenediaminetetraacetic acid; FBS, fetal bovine serum;
Neural logic molecular, counter-intuitive
Keywords: مکانیزم مولکولی; Creative thinking; Boolean logic gates; Molecular mechanism; Transcription regulation; Somatic hypermutation; Neuron
Sry and the hesitant beginnings of male development
Keywords: مکانیزم مولکولی; Sry; Sex determination; Molecular mechanism; Evolution; Testis development; Brain gender;
Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish
Keywords: مکانیزم مولکولی; Anti-androgen; Estrogen; Molecular mechanism; Gene expression; Endocrine disruption; Fish
Understanding the molecular mechanism underlying the presynaptic toxicity of secreted phospholipases A2
Keywords: مکانیزم مولکولی; Venom; Phospholipase A2; Presynaptic neurotoxicity; Molecular mechanism
Comparative Proteome Analysis of Breast Cancer and Adjacent Normal Breast Tissues in Human
Keywords: مکانیزم مولکولی; biomarker; breast cancer; 2D-PAGE; mass spectrometry; molecular mechanism
Molecular mechanisms for maintenance of G-rich short tandem repeats capable of adopting G4 DNA structures
Keywords: مکانیزم مولکولی; Molecular mechanism; G4 DNA structure; G-rich repetitive sequence; hnRNPs
Alternate Structural Conformations of Streptococcus pneumoniae Hyaluronan Lyase: Insights into Enzyme Flexibility and Underlying Molecular Mechanism of Action
Keywords: مکانیزم مولکولی; bacteria; chondroitin; glycan degradation; molecular mechanism; molecular dynamicsCH, unsulfated chondroitin; CHS, chondroitin sulfate; ECM, extracellular matrix of tissues; HA, polymeric hyaluronan; Hyal, hyaluronan lyase; OPLS-AA, optimized potentials f
Notch signaling plays a key role in cardiac cell differentiation
Keywords: مکانیزم مولکولی; Cell differentiation; Notch pathway; Cardiomyocyte; Ventricles; Molecular mechanism
A novel systems biology/engineering approach solves fundamental molecular mechanistic problems in bioenergetics and motility
Keywords: مکانیزم مولکولی; ATP synthase; ATP synthesis; Muscle contraction; Myosin; Molecular mechanism; Torsional mechanism; Rotation-uncoiling-tilt energy storage mechanism; Chemiosmotic theory; Binding change mechanism; Energy transduction; Nanotechnology; Systems biology; First
The molecular mechanisms involved in the cytotoxicity of alkannin derivatives
Keywords: مکانیزم مولکولی; Alkannin derivatives; Cytotoxicity; Redox potential; Molecular mechanism;
Evolutionary and mechanistic relationships between glycosidases acting on α- and β-bonds
Keywords: مکانیزم مولکولی; Glycosidase; Phosphorylase; Molecular mechanism; Evolution; Sugar ring distortion
Bases moléculaires et physiopathologiques des maladies de l'hémoglobine
Keywords: مکانیزم مولکولی; Drépanocytose; Thalassémies; Physiopathologie; Mécanismes moléculaires; Lésions cellulaires; Interactions endothéliales; Gènes modulateurs; Ãpidémiologie; Sickle disease; Thalassemias; Pathophysiology; Molecular mechanism; Cellular defects; Endot
Function of prokaryotic and eukaryotic ABC proteins in lipid transport
Keywords: مکانیزم مولکولی; ABC; ATP binding cassette; APLT; aminophospholipid translocase; Cer; ceramide; FA; fatty acid; GlcCer; glucosylceramide; HDL; high density lipoprotein; LTC; leukotriene C; nbd; [N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]; NBD; nucleotide binding domain;