دانلود مقالات ISI درباره MRM، نظارت چندگانه واکنش + ترجمه فارسی

Simultaneous LC–MS/MS analysis of the biomarkers cAMP and cGMP in plasma, CSF and brain tissue

Keywords: MRM، نظارت چندگانه واکنش; cAMP, cyclic adenosine-3′,5′-monophosphate; cGMP, cyclic guanosine-3′,5′-monophosphate; PDE, phosphodiesterase; LC–MS/MS, liquid chromatography coupled to tandem mass spectrometry; MRM, multiple reaction monitoring; aCSF, artificial cerebrospinal fluid; I

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

A validated bioanalytical method in mouse, rat, rabbit and human plasma for the quantification of one of the steroid glycosides found in Hoodia gordonii extract

Keywords: MRM، نظارت چندگانه واکنش; HPLC, high performance liquid chromatography; FDA, Food and Drug Administration; LLE, liquid–liquid extraction; LC–MS/MS, liquid chromatography tandem mass spectrometry; MRM, multiple reaction monitoring; MTBE, methyl-tert-butyl ether; QC, quality control

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacokinetics of aconitine as the targeted marker of Fuzi (Aconitum carmichaeli) following single and multiple oral administrations of Fuzi extracts in rat by UPLC/MS/MS

Keywords: MRM، نظارت چندگانه واکنش; ACN, acetonitrile; ANOVA, analysis of variance; AUC, area under curve; CL, clearance; HPLC, high performance liquid chromatography; IS, internal standard; MRT, mean residence time; MRM, multiple reaction monitoring; QC, quality control; SE, standard error

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; LC–MS/MS, liquid chromatography–tandem mass spectrometry; HILIC, hydrophilic interaction liquid chromatography; MRM, multiple reaction monitoring; ACN, acetonitrile; MeOH, methanol; IS, internal standard; AD, Alzheimer's disease; PD, Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Direct measurement of free estradiol in human serum by equilibrium dialysis–liquid chromatography–tandem mass spectrometry and reference intervals of free estradiol in women

Keywords: MRM، نظارت چندگانه واکنش; ED, equilibrium dialysis; LC, liquid chromatography; MS/MS, tandem mass spectrometry; MRM, multiple reaction monitoring; LLOQ, lower limit of quantification; ULOQ, upper limit of quantification; SHBG, sex-hormone binding globulinEquilibrium dialysis; Free

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets

Keywords: MRM، نظارت چندگانه واکنش; AUC, area under the plasma concentration–time curve; Cmax, peak plasma concentration; DHR, dihydroresveratrol; GE, grape extract; MRM, multiple reaction monitoring; MRT, mean residence time; PIS, product ion scan; RW, red wine; tmax, time of peak plasma c

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies

Keywords: MRM، نظارت چندگانه واکنش; APAP, acetaminophen; CS, calibration standards; IA, intra-arterial administration; IS, internal standard; LC–MS/MS, liquid chromatography with tandem mass spectrometry; LOQ, limit of quantitation; MRM, multiple reaction monitoring; NaOMe, sodium methoxide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Fast atrazine photodegradation in water by pulsed light technology

Keywords: MRM، نظارت چندگانه واکنش; Pesticide; Decontamination; Water; UV; Pulsed light; PhotoprodutsIS, internal standard; LCMS, liquid chromatography mass spectrometry; MSD, mass selective detector; ESI, electrospray ionization; MRM, multiple reaction monitoring; EIC, extracted ion chroma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Measurement of free and total sialic acid by isotopic dilution liquid chromatography tandem mass spectrometry method

Keywords: MRM، نظارت چندگانه واکنش; LC, liquid chromatography; LC–MS/MS, liquid chromatography tandem mass spectrometry; MRM, multiple reaction monitoring; Neu5Ac, N-Acetylneuraminic Acid; KDN, 2-keto-3-desoxynonic acid; 13C-Neu5Ac, 1,2,3-13C3 N-Acetyl-d-neuraminic Acid; FSA, free sialic ac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Quantification of intracellular and extracellular prostanoids stimulated by A23187 by liquid chromatography/electrospray ionization tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; COX, cyclooxygenase; IS, internal standard; LC/MS/MS, liquid chromatography/tandem mass spectrometry; LLOQ, lower limit of quantification; MRM, multiple reaction monitoring; PG, prostaglandin; TX, thromboxaneProstanoid; LC/MS/MS; Intracellular measurement

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

LC–ESI-MS/MS method for the quantification of entecavir in human plasma and its application to bioequivalence study

Keywords: MRM، نظارت چندگانه واکنش; LC–ESI-MS/MS, liquid chromatography–electro spray ionization-tandem mass spectrometry; MRM, multiple reaction monitoring; EV, entecavir; LM, lamivudine; LLOQ, lower limit of quantification; LOQ, limit of quantification; LQC, low quality control; MQC, medi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Urinary metanephrines by liquid chromatography tandem mass spectrometry: Using multiple quantification methods to minimize interferences in a high throughput method

Keywords: MRM، نظارت چندگانه واکنش; ESI, electrospray ionization; GC–MS, gas chromatography mass spectrometry; LC–MS/MS, liquid chromatography tandem mass spectrometry; LOD, limit of detection; LOQ, limit of quantitation; MN, metanephrine; MRM, multiple reaction monitoring; NMN, normetaneph

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Determination of resveratrol and piceid in beer matrices by solid-phase extraction and liquid chromatography–tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; SPE, solid-phase extraction; LC–ESI-MS/MS, liquid chromatography–electrospray ionization-tandem mass spectrometry; MRM, multiple reaction monitoring; LOD, limit of detection; LOQ, limit of quantification; MF, matrix factor; PE, process efficiencyBeer; Res

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Simultaneous determination of estrogenic and androgenic hormones in water by isotope dilution gas chromatography–tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; BSTFA (99%) + TCMS (1%), N,O-bis(trimethylsilyl) trifluoroacetamide (99%) + trimethylchlorosilane (1%); EI, eleactron ionisation; MW, molecular weight; MRM, multiple reaction monitoring; MDL, method detection level; MBR, membrane bioreactor; HLB, hydrophi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Serum steroid profiling by isotopic dilution-liquid chromatography–mass spectrometry: Comparison with current immunoassays and reference intervals in healthy adults

Keywords: MRM، نظارت چندگانه واکنش; ID-LC–MS/MS, isotopic dilution-liquid chromatography–tandem mass spectrometry; DOC, deoxycorticosterone; DHEA, dehydroepiandrosterone; IS, internal standard; APCI, atmospheric pressure chemical ionization; MRM, multiple reaction monitoring; GC–MS, gas chr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Simultaneous determination of Levetiracetam and its acid metabolite (ucb L057) in serum/plasma by liquid chromatography tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; MRM, multiple reaction monitoring; LEV, Levetiracetam; MS/MS, tandem mass spectrometryLevetiracetam; Levetiracetam metabolite antiepileptic drug; Tandem mass spectrometry

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Liquid chromatography/tandem mass spectrometry study of anti-inflammatory activity of Plantain (Plantago L.) species

Keywords: MRM، نظارت چندگانه واکنش; 12-HETE, 12(S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid; 12-HHT, 12(S)-hydroxy-(5Z,8E,10E)-heptadecatrienoic acid; 12-LOX, 12-lipoxygenase; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; MRM, multiple reaction monitoring; MS2SIM, single-stage mass

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Quantification of sunitinib in mouse plasma, brain tumor and normal brain using liquid chromatography–electrospray ionization-tandem mass spectrometry and pharmacokinetic application

Keywords: MRM، نظارت چندگانه واکنش; LC–MS/MS, liquid chromatography–tandem mass spectrometry; MRM, multiple reaction monitoring; LOQ, limit of quantification; ESI, electrospray ionization; VEGFR, vascular endothelial growth factor receptor; PDGFR, platelet-derived growth factor receptor; c-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Development and validation of a Sensitive bioanalytical method for the quantitative estimation of Pantoprazole in human plasma samples by LC–MS/MS: Application to bioequivalence study

Keywords: MRM، نظارت چندگانه واکنش; LC–MS/MS, liquid chromatography–tandem mass spectrometry; MRM, multiple reaction monitoring; PS, pantoprazole sodium; PSD3, pantoprazole D3; PPIs, proton pump inhibitors; LLOQ, lower limit of quantification; LOQ, Limit of Quantification; LQC, Lower Qualit

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

A novel strategy for reducing phospholipids-based matrix effect in LC–ESI-MS bioanalysis by means of HybridSPE

Keywords: MRM، نظارت چندگانه واکنش; PPT, plasma protein precipitation; ACN, acetonitrile; ESI, electrospray ionization; MRM, multiple reaction monitoring; SPE, solid-phase extraction; MS, mass spectrometerMatrix effects; Phospholipids; Bioanalysis; Mass spectrometry; LC–MS/MS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of N-acetyl Proline–Glycine–Proline (acPGP) in human serum of adults and newborns by liquid chromatography–tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; acPGP, N-acetyl Proline–Glycine–Proline; acPGG, N-acetyl Proline–Glycine–Glycine; IL, interleukin; LC–MS/MS, liquid chromatography coupled with tandem mass spectrometry; ESI, electrospray ionization; MRM, multiple reaction monitoring; I.S., internal stand

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Probenecid, an inhibitor of transmembrane organic anion transporters, alters tissue distribution of DNA adducts in 1-hydroxymethylpyrene-treated rats

Keywords: MRM، نظارت چندگانه واکنش; 1-HMP, 1-hydroxymethylpyrene; LC–MS/MS, liquid chromatography–tandem mass spectrometry; 1-MP, 1-methylpyrene; MPdA, N6-(1-methylpyrenyl)-2′-deoxyadenosine; MPdG, N2-(1-methylpyrenyl)-2′-deoxyguanosine; MRM, multiple reaction monitoring; OAT, organic anion

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Simultaneous quantification of S-adenosyl methionine and S-adenosyl homocysteine in human plasma by stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; HC, high control; HHCY, hyperhomocysteinemia; HPLC, high-performance liquid chromatography; LC, low control; LC–MS/MS, liquid chromatography with tandem mass spectrometry; MAT, methionine adenosyltransferase; MRM, multiple reaction monitoring; MS/MS, tand

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; HPLC, high performance liquid chromatography; TSH, thyroid stimulating hormone; CEA, carcinoembryonic antigen; hCG, human chorionic gonadotropin; MRM, multiple reaction monitoring; PSA, prostate specific antigenImmunoassays; Tandem mass spectrometry; Auto

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones

Keywords: MRM، نظارت چندگانه واکنش; BNAH, benzyldihydronicotinamide riboside; E1-3,4-Q, estrone-3,4-quinone; E2-3,4-Q, estradiol-3,4-quinone; ESI, electrospray ionization; LC/MS, liquid chromatography/mass spectrometry; MD, menadione; MRM, multiple reaction monitoring; MS-MS, tandem mass sp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of metabolites of meisoindigo in rat, pig and human liver microsomes by UFLC–MS/MS

Keywords: MRM، نظارت چندگانه واکنش; CML, chronic myelogenous leukemia; UFLC, ultra fast liquid chromatography; MS, mass spectrometry; MS/MS, tandem mass spectrometry; QTRAP, hybrid triple quadrupole linear ion trap; MRM, multiple reaction monitoring; EPI, Enhanced Product IonIn vitro metabo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Urine acylcarnitine analysis by ESI–MS/MS: A new tool for the diagnosis of peroxisomal biogenesis disorders

Keywords: MRM، نظارت چندگانه واکنش; VLCFA, very long-chain fatty acids; PBDs, peroxisomal biogenesis disorders; GC/MS, gas chromatography/mass spectrometry; CoA, coenzyme-A; ESI–MS/MS, electrospray ionization tandem mass spectrometry; MRM, multiple reaction monitoring; D-BP, D-bifunctional

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

An automated, highly sensitive LC-MS/MS assay for the quantification of the opiate antagonist naltrexone and its major metabolite 6β-naltrexol in dog and human plasma

Keywords: MRM، نظارت چندگانه واکنش; APCI, atmospheric pressure chemical ionization; EDTA, ethylene diamino tetra acetylic acid; LLOQ, lower limit of quantitation; MRM, multiple reaction monitoring; m/z, mass/charge; QC, quality control; R.S.D.%, residual standard deviation in %Naltrexone; 6

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Investigation of the metabolic fate of dihydrocaffeic acid

Keywords: MRM، نظارت چندگانه واکنش; LC–MS, liquid chromatograph with mass spectrometry; MRM, multiple reaction monitoring; m/z, mass to charge ratio; TIC, total in countFerulic acid; Caco-2; Liver metabolism; Glucuronide; Sulfate

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

A simple in vitro model to study the stability of acylglucuronides

Keywords: MRM، نظارت چندگانه واکنش; UDPGA, uridine 5′-diphosphoglucuronic acid; UGTs, uridine 5′-diphosphoglucuronosyl-transferase; MRM, multiple reaction monitoring; ZG, zomepirac acylglucuronides; ibG, ibuprofen acylglucuronides; geG, gemfibrozil acylglucuronide.Carboxylic drug; Acylglucu

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Determination of serum lysophosphatidic acid as a potential biomarker for ovarian cancer

Keywords: MRM، نظارت چندگانه واکنش; ESI, electrospray ionisation; ESI-MS/MS, electrospray ionisation tandem mass spectrometry; HPLC, high performance liquid chromatography; GC, gas chromatography; LPA, lysophosphatidic acid; MRM, multiple reaction monitoring; R.S.D., relative standard devia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Quantification of urinary 8-iso-PGF2α using liquid chromatography-tandem mass spectrometry and association with elevated troponin levels

Keywords: MRM، نظارت چندگانه واکنش; LC-MS/MS, liquid chromatography-tandem mass spectrometry; ESI-MS, electrospray ionization mass spectrometry; MRM, multiple reaction monitoring; APCI, atmospheric pressure chemical ionization; SPE, solid phase extraction; TMS, trimethylsilyl; PFB, Pentaflu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

High-throughput urine screening for Smith–Lemli–Opitz syndrome and cerebrotendinous xanthomatosis using negative electrospray tandem mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; CV, cone voltage; CE, collision energy in electron volts; CPG, cholestane-pentol glucuronide; KPDDS, keto-pregnadien-diol sulfate; TMS, tandem mass spectrometry; MRM, multiple reaction monitoring; SLOS, Smith–Lemli–Opitz syndrome; CTX, cerebrotendinous xa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells

Keywords: MRM، نظارت چندگانه واکنش; GSH, Glutathione; GST, Glutathione S-transferase; LC/MS/MS, liquid chromatography/tandem mass spectrometry; mEHI, microsomal epoxide hydrolase inhibitor; MRM, multiple reaction monitoring; NADPH, nicotinamide adenine dinucleotide phosphate; sEHI, soluble

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Determination of trace amount of microcystins in water samples using liquid chromatography coupled with triple quadrupole mass spectrometry

Keywords: MRM، نظارت چندگانه واکنش; CE, collision energy; CID, collision indused decomposition; LODs, Limits of detection; LOQs, limits of quantification; MC, microcystin; MRM, multiple reaction monitoring; m/z, mass to charge ratioMicrocystins; Liquid chromatography; Triple quadrupole mass

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه