
Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series of μ-opioid receptor antagonists
Keywords: رویکرد چندگانه; μ-Opioid receptor antagonist; Multivalent approach; Peripherally-restricted; Opioid-induced constipation;