Keywords: فیبروبلاست جنینی جنینی; ACL; ATP citrate lyase; AMPK; adenosine monophosphate kinase; ARG1; l-arginine-metabolizing enzyme arginase 1; BCAA; branched-chain amino acid; Bcl2; B-cell lymphoma 2; CAF; cancer-associated fibroblast; CIC; cancer-initiating cell; COX2; cytochrome oxida
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Keywords: فیبروبلاست جنینی جنینی; 8-oxoG; 7,8-dihydro-8-oxoguanine; AECs; airway epithelial cells; AHR; airway hyperresponsiveness; APE1; AP-endonuclease 1; AP sites; apurinic/apyrimidinic site; BER; base excision repair; BALF; bronchoalveolar lavage fluid; CA; comet assay; DSB; double-st
Keywords: فیبروبلاست جنینی جنینی; MEF; murine embryonic fibroblast; AMC; 7-amino-4-methylcoumarin; Suc-LLVY-AMC; the succinylated peptide N-succinyl-leucine-leucine-valine-tyrosine-7-amino-4-methylcoumarin (used as a peptide substrate to estimate proteolytic capacity); PBS; phosphate-buff
Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation
Keywords: فیبروبلاست جنینی جنینی; AKR1C1; aldo-keto reductase family 1 member C1; DMEM; sodium pyruvate free Dulbecco's modified Eagle's medium; DMNQ; 2,3-dimethoxy-1,4-naphthoquinone; dtBHQ; 2,5-di-tert-butylhydroquinone; EGCG; epigallocatechin-3-gallate; FBS; fetal bovine serum; HEPES;
Glutathione S-transferase pi expression regulates the Nrf2-dependent response to hormetic diselenides
Keywords: فیبروبلاست جنینی جنینی; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; ARE; antioxidant response element; EpRE; electrophile response element; HO-1; heme oxygenase-1; ROS; reactive oxygen species; (PhSe)2; diphenyl diselenide; GSTP
Oxidative stress impairs multiple regulatory events to drive persistent cytokine-stimulated STAT3 phosphorylation
Keywords: فیبروبلاست جنینی جنینی; JAK; Janus kinase; STAT; Signal Transducer and Activator of Transcription; TC-PTP; T-cell protein tyrosine phosphatase; SOCS3; suppressor of cytokine signalling 3; H2O2; hydrogen peroxide; LIF; leukemia inhibitory factor; OSM; oncostatin M; MAPK; mitogen-
Presenilins are novel substrates for TRAF6-mediated ubiquitination
Keywords: فیبروبلاست جنینی جنینی; AD; Alzheimer's disease; AICD; APP intracellular domain; APH-1; anterior pharynx-defective-1; APP; Amyloid precursor protein; Aβ; Amyloid β; C99; 99-amino acid APP C-terminal fragment; ER; Endoplasmic reticulum; FAD; Familial Alzheimer's disease; HEK293
Identification and characterization of bi-thiazole-2,2â²-diamines as kinase inhibitory scaffolds
Keywords: فیبروبلاست جنینی جنینی; MAPK; mitogen-activated protein kinase; JD; JNK Docking; ERK; extracellular signal signal-regulated kinase; JNK; c-Jun N-terminal kinase; MKK; MAPK kinase; GST; glutathione S-transferase; GSH; glutathione; JIP; JNK-interacting protein; DCX; doublecortin X
Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17
Keywords: فیبروبلاست جنینی جنینی; ADAM; A Disintegrin And Metalloprotease; TNF-α; Tumor Necrosis Factor-α; TNFR; TNF receptor; EGF; Epidermal Growth Factor; PMA; phorbol 12-myristate 13-acetate; LPA; lysophosphatidic acid; CHX; Cycloheximide; GPI; glycosylphosphatidylinositol; MAPK; mit
Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim
Keywords: فیبروبلاست جنینی جنینی; CHOP; C/EBP homologous protein; eIF2a; eukaryotic initiation factor-2a; ER; endoplasmic reticulum; GRP78; glucose regulated protein 78; Hyp-PDT; hypericin-based photodynamic therapy; ICD; immunogenic cell death; MEF; murine embryonic fibroblast; PERK; pan
Targeting PI3K Signaling as a Therapeutic Approach for Colorectal Cancer
Keywords: فیبروبلاست جنینی جنینی; Colon Cancer; Neoplasm; Signal Transduction; Genetics; Tumor; CRC; colorectal cancer; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; GPCR; G-protein-coupled receptor; IRS1; insulin receptor substrate 1; MEF; murine embryonic fibro
Truncation of the Catalytic Domain of the Cylindromatosis Tumor Suppressor Impairs Lung Maturation
Keywords: فیبروبلاست جنینی جنینی; JNK; c-Jun kinase; MEF; murine embryonic fibroblast; NF-κB; nuclear factor κB; NSCLC; non-small cell lung cancer; TNF; tumor necrosis factor; TRAF; TNF-receptor-associated factor;
Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis
Keywords: فیبروبلاست جنینی جنینی; CA-074; N-(l-3-trans-propylcarbamoyloxirane-2-carbonyl)-l-isoleucyl-l-proline; CREG; Cellular repressor of E1A-stimulated genes; E-64; N-(l-3-trans-carboxyoxirane-2-carbonyl)-l-leucyl-(4-guanidino)-butane; endo H; endo-β-N-acetyl-glucosaminidase H; ER; e