Keywords: اتصال گیرنده ماکارانیک; OAB; overactive bladder; CNS; central nervous system; QOL; quality of life; ACh; acetylcholine; BBB; blood-brain barrier; DEO; N-desethyloxybutynin; DPr-P-4; 1-methyl-4-piperidyl benzilate hydrochloride; P-4(Nâ¯ââ¯O); 1-methyl-4-piperidyl diphenylprop