TNFα triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNFα responses of the parental cells
Keywords: TNFα; TNFR1; TRADD; Extracellular vesiclesTNFα, tumor necrosis factor-α; TNFR1, TNF receptor-1; EVs, extracellular vesicles; TRADD, TNFR-associated death domain; A-SMase, acid sphingomyelinase; N-SMase, neutral sphingomyelinase; GEF, guanine nucleotide ex