Structural and functional changes in a synthetic S5 segment of KvLQT1 channel as a result of a conserved amino acid substitution that occurs in LQT1 syndrome of human
Keywords: CD, circular dichroism; Fmoc, N-(9-fluorenyl)methoxycarbonyl; HPLC, high performance liquid chromatography; Kv, voltage gated potassium channels; LQTS, long QT syndrome; NBD, 7-nitrobenz-2-oxa-1,3-diazole; PBS, phosphate buffered saline (pH 7.4); PC, phos