
Structure–activity relationship of ibogaine analogs interacting with nicotinic acetylcholine receptors in different conformational states
Keywords: AChR, nicotinic acetylcholine receptor; NCA, noncompetitive antagonist; PCP, phencyclidine, (3S-trans)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine; [3H]TCP, piperidyl-3, 4-3H(N)]-(N-(1-(2 thienyl)cyclohexyl)-3, 4-piperidine; CCh, carb