دانلود مقالات ISI درباره Nce, New Chemical Entity + ترجمه فارسی

اکوکاردیوگرافی فشار همراه با آزمون استرس دارویی برای تشخیص زودهنگام از کاردیومیوپاتی ناشی از آنتراسیکلین

Strain echocardiography combined with pharmacological stress test for early detection of anthracycline induced cardiomyopathy

Keywords: 2DSE, 2D speckle echocardiography; FS, fractional shortening; HR, heart rate; IP, intraperitoneal; LV, left ventricle; NCE, new chemical entity; REST, at rest2-D speckle; Cardiomyopathy; Cardiotoxicity; Dobutamine stress; Doxorubicin; Echocardiography; Me

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

سنتز و ارزیابی بیولوژیکی مشتقات di-N-oxide quinoxaline با فعالیت تریپانوپلیکیدی در شرایط آزمایشگاهی

Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity

Keywords: BFX, benzofuroxan; CD, chagas disease; Nfx, Nifurtimox; Bnz, Benznidazol; NCE, new chemical entity; N.T., not tested; NTD, Neglected Tropical Diseases; PGI, percentage of growth inhibition; SI, selectivity index; TPP, Target Product ProfileChagas disease;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of anti-HIV active dicaffeoylquinic- and tricaffeoylquinic acids in Helichrysum populifolium by NMR-based metabolomic guided fractionation

Keywords: SANBI, South African National Biodiversity Institute; NCE, new chemical entity; PCA, principal component analysis; HCA, hierarchical cluster analysis; OPLSs, orthogonal projections to latent structures; OPNG, ortho-nitrophenyl-galactopyranoside; OPN, orth

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The value of nature's natural product library for the discovery of New Chemical Entities: The discovery of ingenol mebutate

Keywords: NCE, New Chemical Entity; FDA, Food and Drug Administration; PKC, protein kinase C; QIMR, Queensland Institute of Medical Research; BCC, basal cell carcinoma; SCC, squamous cell carcinoma; IEC, intra-epithelial carcinoma; HPTLC, high performance thin laye

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity

Keywords: NCE, new chemical entity; NBE, new biological entity; FDA, Food and Drug Administration; EU, European Union; CYP, cytochrome; GGT, γ-glutamyl transferase; MDR, multidrug-resistance; NAbs, neutralizing antibodies; MDCK, Mandin–Darby Canine Kidney; ECM, ext

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2012 سفارش ترجمه

Functional biomarkers of musculoskeletal syndrome (MSS) for early in vivo screening of selective MMP-13 inhibitors

Keywords: MSS, Musculoskeletal Syndrome; LFSS, Landing Foot Splay Separation; PV, Paw Volume; NCE, new chemical entity; MMP, matrix metalloproteinaseMusculoskeletal syndrome; Marimastat; Rotarod; Histology; Matrix metalloproteinase; Biomarker

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

A framework to assess the translation of safety pharmacology data to humans

Keywords: ADRs, Adverse drug reactions; NCE, New chemical entity; FDA, Food and Drug Administration; hERG, Human Ether-a-go-go Related Gene; FTIM, First Time In Man; HESI, Health and Environmental Science Institute; ICH, International Conference on Harmonisation; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Drug induced shortening of the QT/QTc interval: An emerging safety issue warranting further modelling and evaluation in drug research and development?

Keywords: APD, action potential duration; ATP, adenosine triphosphate; CRO, Contract Research Organisation, ECG, electrocardiogram; LVWP, left ventricular wedge preparation; NCE, new chemical entity; QTc, rate corrected QT interval; QT/QTc, QT and/or QTc-interval;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه