دانلود مقالات ISI درباره تولید نوروژنیک + ترجمه فارسی

Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis

Keywords: تولید نوروژنیک; Multiple sclerosis; Mitochondrial dysfunction; Neurodegeneration; Nitric oxide; Microglia; Neuroprotective strategies;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2

Keywords: تولید نوروژنیک; Anti-DIG; antibody against digoxigenin; APES; 3-aminopropyl-triethoxysilane; ARE; antioxidant response element; BSA; bovine serum albumin; CNC; coding-non-coding; Cy3; cyanine dye 3; DA; dopamine; DAPI; 4,6-diamidino-2-phenylindole; DEPC; Diethyl pyrocarb

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Astrocyte elevated gene-1 is a novel regulator of astrogliosis and excitatory amino acid transporter-2 via interplaying with nuclear factor-κB signaling in astrocytes from amyotrophic lateral sclerosis mouse model with hSOD1G93A mutation

Keywords: تولید نوروژنیک; ALS; Amyotrophic lateral sclerosis; AEG-1; Astrocyte elevated gene-1; ACM; astrocyte-conditioned medium; CBP; CREB-binding protein; COX-2; Cyclooxygenase-2; DMSO; dimethyl sulfoxide; DL-NBP; DL-3-n-butylphthalide; DMEM; Dulbecco modified Eagle medium; EAA

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Resveratrol protects neuronal-like cells expressing mutant Huntingtin from dopamine toxicity by rescuing ATG4-mediated autophagosome formation

Keywords: تولید نوروژنیک; Huntington; Parkinson; Dopaminergic neurons; Autophagy; Anti-oxidant; Neurodegeneration; CD; Cathepsin D; DA; dopamine; E2; 17-β-Estradiol; HD; Huntington Disease; Htt; Huntingtin; LIR; LC3-interacting region; PE; PhosphatydilEthanolamin; RV; Resveratrol

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-neuroinflammatory effects of Ginkgo biloba extract EGb761 in LPS-activated primary microglial cells

Keywords: تولید نوروژنیک; Neurodegeneration; Prostaglandin E2; Cyclooxygenase; Cytokines; Neuroinflammation; Alzheimer's disease; EGb 761; Extract Ginkgo biloba 761; PG; prostaglandin; COX; cyclooxygenase; cPLA2; cytosolic phospholipase A2; IkappaBalpha; inhibitor of kappa B alpha

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Kaempferol Inhibits Extra-synaptic NMDAR-Mediated Downregulation of TRkβ in Rat Hippocampus During Hypoxia

Keywords: تولید نوروژنیک; DCFHDA; 2,7-dichlorofluorescein-diacetate; EDTA; ethylene diamine tetraacetate; GPx; glutathione peroxidase; HBSS; Hank's balanced salt solution; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; NMDARs; N-methyl-d-aspartate receptor; PBS; phos

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Autoimmunity in multiple sclerosis: role of sphingolipids, invariant NKT cells and other immune elements in control of inflammation and neurodegeneration

Keywords: تولید نوروژنیک; Ag; antigen; APC; antigen presenting cell; BBB; blood brain barrier; BCR; B cell receptor; BDNF; brain-derived neurotrophic factor; CIS; clinically isolated syndrome; CLR; C-type lectin receptor; CNS; central nervous system; CSF; cerebrospinal fluid; DAMP

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Multifunctional molecule ERp57: From cancer to neurodegenerative diseases

Keywords: تولید نوروژنیک; 1α,25(OH)2D3; 1,25-dihydroxyvitamin D3; ADAM10; a disintegrin and metalloproteinase 10; AIF; apoptosis-inducing factor; AP-1; activator protein 1; ATRA; all-trans retinoic acid; BMP-2; bone morphogenic protein 2; CLNX; calnexin; CRT; calreticulin; ECM; e

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS

Keywords: تولید نوروژنیک; Cannabinoids; Anandamide; HIV-1 Tat; Neurodegeneration; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Protein phosphatase 2ACα gene knock-out results in cortical atrophy through activating hippo cascade in neuronal progenitor cells

Keywords: تولید نوروژنیک; Neurodegeneration; Cerebral cortex; Neuroprojenitor cell; Hippo cascade; Transcription;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Inducible overexpression of endothelial proNGF as a mouse model to study microvascular dysfunction

Keywords: تولید نوروژنیک; Neurotrophin; Nerve growth factor; Diabetic retinopathy; Acellular capillary; Apoptosis; Neurodegeneration; Inflammation; Barrier dysfunction;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration

Keywords: تولید نوروژنیک; Alzheimer's disease; Autophagy; Parkinson's disease; Polyphenols; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

(−)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia

Keywords: تولید نوروژنیک; Alzheimer's disease; Depression; Neurodegeneration; Neurogenesis; Neuroprotection; P7C3; TgF344-AD;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-16 targets mRNA involved in neurite extension and branching in hippocampal neurons during presymptomatic prion disease

Keywords: تولید نوروژنیک; miR-16; Prion; Presymptomatic disease; Neurodegeneration; Neurite; microRNA targets; MAPK/ERK signaling; Ago2 RIP-Chip;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Minocycline protects developing brain against ethanol-induced damage

Keywords: تولید نوروژنیک; Apoptosis; Development; Fetal alcohol syndrome; Inflammation; Microglia; Neurodegeneration; AD; Alzheimer's disease; CNS; central nervous system; FASD; fetal alcohol spectrum disorder; GSK3β; Glycogen synthase kinase 3 beta; Iba-1; ionized calcium bindin

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation

Keywords: تولید نوروژنیک; aa; amino acid; Aβ; β-amyloid; AD; Alzheimer's disease; APP; amyloid precursor protein; CBD; Cas-binding domain; DIV; days in vitro; GEF; guanine nucleotide exchange factor; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; NBD; NSP3-binding domain; NSP3; nove

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

The role of the cerebellum in multiple sclerosis-150 years after Charcot

Keywords: تولید نوروژنیک; Cerebellum; Multiple sclerosis; Cognition; Atrophy; Neurodegeneration; Magnetic resonance imaging; Depth-sensing computer vision;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Non-cell-autonomous actions of α-synuclein: Implications in glial synucleinopathies

Keywords: تولید نوروژنیک; Astrocyte; Microglia; Neurodegeneration; Neuroinflammation; Parkinson disease; Protein aggregation; Multiple system atrophy; AD; Alzheimer disease; CJD; Creutzfeldt-Jakob disease; CNP; 3′-cyclic nucleotide 3′-phosphodiesterase; CSF; cerebrospinal fl

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Toxicity and aggregation of the polyglutamine disease protein, ataxin-3 is regulated by its binding to VCP/p97 in Drosophila melanogaster

Keywords: تولید نوروژنیک; AAA ATPase; Ataxia; Ataxin-3; Deubiquitinase; Machado-Joseph Disease; Neurodegeneration; Polyglutamine; Spinocerebellar Ataxia Type 3; VCP/p97;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

Keywords: تولید نوروژنیک; MPS; α-methyl-α-phenylsuccinimide; AD; Alzheimer's disease; ALS; Amyotrophic lateral sclerosis; BSA; Bovine serum albumin; CNS; Central nervous system; DRS; Dent's Ringer solution; FTLD; Frontotemporal lobar degeneration; MOO; Multi-objective optimisati

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

Regulatory-accepted drug development tools are needed to accelerate innovative CNS disease treatments

Keywords: تولید نوروژنیک; ACR; American College of Radiology; AD; Alzheimer disease; ADNI; Alzheimer's Disease Neuroimaging Initiative; ALS; Amyotrophic Lateral Sclerosis; ASD; Autism Spectrum Disorder; BBB; Blood-Brain-Barrier; BEST; Biomarkers, Endpoints and other Tools; BLA; Bi

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه

A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer's models

Keywords: تولید نوروژنیک; Neurodegeneration; Neuroinflammation; SPP1; ETA-1; Vascular amyloid;

دانلود رایگان متن کامل مقاله ISI 66 صفحه سال انتشار : 2018 سفارش ترجمه

DYRK1A kinase inhibition with emphasis on neurodegeneration: A comprehensive evolution story-cum-perspective

Keywords: تولید نوروژنیک; Amyloid precursor protein; Down's syndrome critical region (DSCR) Alzheimer's disease; DYRK1A; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 67 صفحه سال انتشار : 2018 سفارش ترجمه

Crosstalk between Rac1-mediated actin regulation and ROS production

Keywords: تولید نوروژنیک; Rac1; NADPH oxidases; Reactive oxygen species (ROS); Actin cytoskeleton regulation; ROS and actin crosstalk; Redox signaling; Polarity; Scaffolding proteins; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

Role of the Fyn-PKCδ signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy

Keywords: تولید نوروژنیک; Microglia; Neuroinflammation; Status epilepticus; Epileptogenesis; Video-EEG; Neurodegeneration; Nitro-oxidative stress;

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2018 سفارش ترجمه

Original ArticleRecessive AFG3L2 Mutation Causes Progressive Microcephaly, Early Onset Seizures, Spasticity, and Basal Ganglia Involvement

Keywords: تولید نوروژنیک; AFG3L2; basal ganglia; early onset seizures; neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

SIRT1 and NAD + precursors: Therapeutic targets in multiple sclerosis a review

Keywords: تولید نوروژنیک; Multiple sclerosis; EAE; Neurodegeneration; NAD; SIRT1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Calcium Hypothesis of Alzheimer's disease and brain aging: A framework for integrating new evidence into a comprehensive theory of pathogenesis

Keywords: تولید نوروژنیک; Calcium; Hypothesis; Aging; Alzheimer's disease; Dementia; Neuron; Neurodegeneration; Model; Aging mechanism; Brain; Performance; Development; Amyloid; Tau;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleGeneration of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

Keywords: تولید نوروژنیک; iPSCs; Postmortem; Autopsy; PBMCs; Neurodegeneration; Disease modeling; Parkinson disease; Neuropathological confirmation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Autoantibodies to heterogeneous nuclear ribonuclear protein A1 (hnRNPA1) cause altered 'ribostasis' and neurodegeneration; the legacy of HAM/TSP as a model of progressive multiple sclerosis

Keywords: تولید نوروژنیک; Neurodegeneration; RNA; Multiple sclerosis; Autoimmunity; RNA binding protein; HTLV-1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Modeling Niemann Pick type C1 using human embryonic and induced pluripotent stem cells

Keywords: تولید نوروژنیک; Niemann Pick type C1; Human embryonic stem cells; Human induced pluripotent stem cells; Neurodegeneration; Models of disease; Drug screening; Autophagy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

RevisiónEl modelo de 6-hidroxidopamina y la fisiopatología parkinsoniana: nuevos hallazgos en un viejo modeloThe 6-hydroxydopamine model and parkinsonian pathophysiology: Novel findings in an older model

Keywords: تولید نوروژنیک; Apoptosis; Vía nigroestriatal; Neurodegeneración; Substantia nigra; Neuroinflamación; Estrés oxidativo; Apoptosis; Nigrostriatal pathway; Neurodegeneration; Substantia nigra; Neuroinflammation; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Radiosynthesis of [18F]AV1451 in pharmaceutical conditions and its biological characteristics

Keywords: تولید نوروژنیک; TAU protein; Radiopharmaceutical drug; Plasma protein binding; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperImmunomodulatory properties of 1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxamide derivative VL15

Keywords: تولید نوروژنیک; Immunomodulation; Intestinal absorption; Blood-brain barrier diffusion; Cannabinoid CB2 receptor; 1,8-Naphthyridine-3-carboxamide derivative; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?

Keywords: تولید نوروژنیک; Reactive oxygen species; 8-oxo-7, 8-dihydroguanine; 8-oxo-dGTP; Base excision repair; OGG1; MUTYH; Carcinogenesis; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

New rapid, accurate T2 quantification detects pathology in normal-appearing brain regions of relapsing-remitting MS patients

Keywords: تولید نوروژنیک; AUC; area under the curve; B1 +;  transmit field; EMC; echo modulation curve; FLAIR; fluid-attenuated inversion recovery; SPACE; sampling perfection with application-optimized contrasts using different flip angle evolution; MPRAGE; magnetization-prepare

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Oleuropein shows copper complexing properties and noxious effect on cultured SH-SY5Y neuroblastoma cells depending on cell copper content

Keywords: تولید نوروژنیک; Oleuropein; Copper; SH-SY5Y; Cancer; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

14-3-3 adaptor protein-protein interactions as therapeutic targets for CNS diseases

Keywords: تولید نوروژنیک; 14-3-3; Axon; Parkinson's; LRRK2; Neurodegeneration; Fusicoccin; Drug;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

Keywords: تولید نوروژنیک; Microglia; Neuroinflammation; Beta-amyloid; Neurodegeneration; Early-onset Alzheimer's disease; Late-onset Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Cell cycle activation in p21 dependent pathway: An alternative mechanism of organophosphate induced dopaminergic neurodegeneration

Keywords: تولید نوروژنیک; Dichlorvos; Oxidative stress; p21; Cyclin-D1; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Reconsidering the role of glial cells in chronic stress-induced dopaminergic neurons loss within the substantia nigra? Friend or foe?

Keywords: تولید نوروژنیک; α-Synuclein; Astrocytes; Chronic stress; Microglia; Neurodegeneration; Oxidative stress; Substantia nigra;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

MLF1 is a proapoptotic antagonist of HOP complex-mediated survival

Keywords: تولید نوروژنیک; Apoptosis; Myeloid leukemia factor 1; HS1-associated protein X-1; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Roles for the VCP co-factors Npl4 and Ufd1 in neuronal function in Drosophila melanogaster

Keywords: تولید نوروژنیک; Proteasome; TDP-43 accumulation; Neurodegeneration; Drosophila; ALS; amyotrophic lateral sclerosis; IBMPDF; inclusion body myopathy with Paget's disease of the bone and frontotemporal dementia; NMJ; neuromuscular junction; Npl4; nuclear protein localizati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Methamphetamine potentiates HIV-1gp120-induced microglial neurotoxic activity by enhancing microglial outward K+ current

Keywords: تولید نوروژنیک; HIV protein; Drug abuse; Microglia; Voltage-gated K channel; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites

Keywords: تولید نوروژنیک; Ataxin-3; Spinocerebellar ataxia type 3; Mass spectrometry; Neurodegeneration; Ubiquitination; Phosphorylation; DUB; deubiquitinating enzyme;; HD; Huntington's disease; HEK; human embryonic kidney;; LC-MS/MS; liquid chromatography tandem mass spectrometry

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

SIRT3 and mitochondrial metabolism in neurodegenerative diseases

Keywords: تولید نوروژنیک; Amyotrophic lateral sclerosis; Mitochondria; Energy balance; Neurodegeneration; SIRT3; AD; Alzheimer's disease; ALS; Amyotrophic Lateral Sclerosis; GSH; reduced glutathione; GSSG; oxidized glutathione; IDH2; isocitrate dehydrogenase 2; LCAD; long-chain ac

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

URB597 reduces biochemical, behavioral and morphological alterations in two neurotoxic models in rats

Keywords: تولید نوروژنیک; Neurodegeneration; Mitochondrial energy depletion; Oxidative damage; Endocannabinoid system; Fatty acid amide hydrolase inhibition; URB597; Neuromodulation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Chronic dexamethasone treatment results in hippocampal neurons injury due to activate NLRP1 inflammasome in vitro

Keywords: تولید نوروژنیک; Glucocorticoids; NLRP-1 inflammasome; Neuroinflammation; Neurodegeneration; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Exposures to fine particulate matter (PM2.5) and ozone above USA standards are associated with auditory brainstem dysmorphology and abnormal auditory brainstem evoked potentials in healthy young dogs

Keywords: تولید نوروژنیک; Air pollution; Ozone; PM 2.5; Brainstem auditory nuclei; Ventral cochlear nuclei; Medial superior olive; Dysmorphology; Neurodegeneration; BAEPs; Dogs; Mexico City;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewParkin and PINK1 functions in oxidative stress and neurodegeneration

Keywords: تولید نوروژنیک; PINK1; Parkin; Ubiquitin; Neurodegeneration; Oxidative stress; Mitophagy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه