
Biochemical mechanism of DSB end resection and its regulation
Keywords: DSB, double-strand break; HR, homologous recombination; NHEJ, nonhomologous end joining; MMEJ, microhomolgy-mediated end joining; MRN, MRE11–RAD50–NBS1 complex; RPA, replication protein AResection; Recombination; Double-strand breaks; Nucleases; Helicases