Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
Keywords: Dapivirine; TMC120-R147681; Drug design; Drug resistance; Etravirine; TMC125-R165335; 3DSAR; Three-dimensional structure-activity relationships; DAPY; Diarylpyrimidine; DATA; Diaryltriazine; dsDNA; Double-stranded DNA; HAART; Highly active antiretroviral