Synergistic effect of basic residues at positions 14–15 of nociceptin on binding affinity and receptor activation
Keywords: Basic amino acids; Antagonist; Nociceptin; Synergistic potentiation; SuperagonistBAEE, benzoyl-l-arginine ethyl ester; BCA, bicinchoninic acid; MALDI-TOF, matrix-assisted laser desorption ionization time-of-flight; Noc, nociceptin; RP-HPLC, reversed-phase