The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core
Keywords: ATP, adenosine triphosphate; βME, β-mercaptoethanol; CT, C-terminus; GTP, guanosine triphosphate; HAP, 6-hydroxylaminopurine; HSP, heat shock protein; ITP, inosine triphosphate; ITPA, inosine triphosphate pyrophosphatase; NT, N-terminus; NUDT16, nudix-typ