Synthesis of diastereomeric 3-hydroxy-4-pyrrolidinyl derivatives of nucleobases
Keywords: آنالوگهای هسته ای; Tartaric acid; Pyrrolidine derivatives; Nucleoside analogs; Nucleobase;
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Tezacitabine enhances the DNA-directed effects of fluoropyrimidines in human colon cancer cells and tumor xenografts
Keywords: آنالوگهای هسته ای; Combination chemotherapy; Colon cancer; Tezacitabine; FMdC; Nucleoside analogs; Fluoropyrimidines
Novel selective human mitochondrial kinase inhibitors: Design, synthesis and enzymatic activity
Keywords: آنالوگهای هسته ای; Design; Synthesis; Nucleoside analogs; Human TK2 inhibitors
Mitsunobu reactions of nucleoside analogs using triisopropyl phosphite-DIAD
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Mitsunobu reaction; Phosphites;
A highly efficient microwave-assisted solvent-free synthesis of α- and β-2â²-deoxy-1,2,3-triazolyl-nucleosides
Keywords: آنالوگهای هسته ای; 1,3-Dipolar cycloaddition; Microwave activation; Cu(I)/SiO2; Regiocontrolled process; Nucleoside analogs;
Medication-induced exacerbation of neuropathy in Charcot Marie Tooth Disease
Keywords: آنالوگهای هسته ای; Toxic neuropathy; Vincristine; Chemotherapy; Nucleoside analogs; Hereditary neuropathy; Drug-induced neuropathy
The incorporation of nucleoside analogs by human immunodeficiency virus type 1 reverse transcriptase decreases in the presence of polyamines
Keywords: آنالوگهای هسته ای; RT, reverse transcriptase; HIV-1, human immunodeficiency virus type-1; NRTI, nucleoside RT inhibitors; NA, nucleoside analogs; DDDP, DNA-dependent DNA polymerization; RDDP, RNA-dependent DNA polymerizationHIV-1; Reverse transcriptase; Nucleoside analogs;
Application of the cycloSal-prodrug approach for improving the biological potential of phosphorylated biomolecules
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Antiviral agent; cycloSal-pronucleotides; Carbohydrate drugs
In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance
Keywords: آنالوگهای هسته ای; Hepatitis C virus; Treatment; NS5B polymerase; Inhibitors; Drug resistance; Nucleoside analogs; Combination therapy
Pharmacology of current and promising nucleosides for the treatment of human immunodeficiency viruses
Keywords: آنالوگهای هسته ای; Antiviral agents; Pharmacology; Nucleoside analogs; HIV
Synthesis of mono- and polyhydroxylated cyclobutane nucleoside analogs
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Mitsunobu reaction; Hydroboration; Dihydroxylation;