O6-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
Keywords: O6-meG، O6-متیل گوانین; AG, anaplastic glioma; BCNU, 1,3-bis(2-chloroethyl)-1-nitrosourea; CCNU, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea; GBM, glioblastoma; HR, hazard ratio; O6-meG, O6-methylguanine; MGMT, O6-methylguanine-DNA methyltransferase; MSP, methylation-specific P