Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage
Keywords: MMS, methyl methanesulfonate; O6meG, O6-methylguanine; MNNG, N-methyl-N′-nitro-N-nitrosoguanidine; N7meG, N7-methylguanine; N3meA, N3-methyladenine; BER, base excision repair; SSB, single-strand break; MGMT, O6meG-DNA methyltransferase; DSB, double-strand