
Functional properties and active-site topographies of factor X Gla- and prothrombin Gla-domain chimeras of activated protein C
Keywords: FX; factor X; FVa; activated factor V; Gla; γ-carboxyglutamic acid; APC; activated protein C; APC-PTGla; a chimeric APC in which the Gla-domain and hydrophobic stack (residues 1-46) of the molecule has been replaced with the corresponding regions of pr