Keywords: رقیق کننده ارگانیک; ASBT; apical sodium-dependent bile acid transporter; ASDs; amorphous solid dispersions; BACS; bile acid-CoA synthase; BAT; bile acid-amino acid transferase; BCS; biopharmaceutics classification system; BSH; bile salt hydrolase; C4; 7α-hydroxy-4-cholesten
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Keywords: رقیق کننده ارگانیک; Drug interactions; Hepatic transport; Transporters; ABC transporters; Bile acid transporters; BSEP; bile salt export pump; DILI; drug-induced liver injury; FXR; farnesoid X receptor; MDR; multidrug resistance protein; MRP; multidrug resistance-associated
Keywords: رقیق کننده ارگانیک; ABCB; ATP-binding cassette sub-family B; Apo; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BDL; bile duct ligation; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; C/EBP; CCAAT-enhancer-binding protein; C
Nuclear receptor FXR, bile acids and liver damage: Introducing the progressive familial intrahepatic cholestasis with FXR mutations
Keywords: رقیق کننده ارگانیک; NR; nuclear receptor; FXR; farnesoid X receptor; RXR; retinoid X receptor; PXR; pregnane X receptor; VDR; Vitamin D receptor; TGR5; G protein-coupled bile acid receptor; Lrh1; liver receptor homolog 1; Mdr; multidrug resistance protein; Abcb4; ATP Bindi
Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion
Keywords: رقیق کننده ارگانیک; Biliary excretion; PPARα; Bile acids; Gender difference; 1oBAs; Primary bile acids; 2oBAs; secondary bile acids; 12-OH; 12-hydroxylated bile acid; Asbt; apical sodium-dependent bile acid transporter; BA; bile acid; Baat; bile acid CoA:amino acid N-acyltr
Transhepatic bile acid kinetics in pigs and humans
Keywords: رقیق کننده ارگانیک; Bile acids; TGR5; Porcine; Postprandial; Portal concentrations; BAs; bile acids; ASBT; apical sodium-dependent bile acid transporter; OST; organic solute transporter; NTCP; taurocholate cotransporting polypeptide; OATP; organic anion transporting polypept
Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice
Keywords: رقیق کننده ارگانیک; Aryl hydrocarbon receptor; TCDD; Bile acids; Biliary excretion; Taurodeoxycholic acid; Cyp8b1; 1°BAs; Primary bile acids; 2°BAs; Secondary bile acids; 6-OH; 6-hydroxylated (6-OH); 12-OH; 12α-hydroxylated; Abc; ATP-binding cassette; AhR; Aryl hydrocarbo
Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes
Keywords: رقیق کننده ارگانیک; ABC; ATP-binding cassette transporter; AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase; AhR; arylhydrocarbon receptor; AKR1C1; aldo-keto reductase 1C1; APO; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BAs; bile acids; BSEP; b
Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2
Keywords: رقیق کننده ارگانیک; Epigallocatechin gallate; Bile formation; Cholestasis; Bile acids; Asbt; apical sodium-dependent bile salt transporter; ALT; alanine transaminase; AST; aspartate transaminase; Bsep; bile salt exporting pump; CDCA; chenodeoxycholic acid; Cyp7a1; cholestero
Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition
Keywords: رقیق کننده ارگانیک; Glycoconjugated bile acids; Tauroconjugated bile acids; Ileum; Liver; Nuclear receptor; ACA; allocholic acid; BA; bile acid; BSEP; bile salt export pump; CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; FGF; fibroblast growth factor; F
Research ArticleMouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism
Keywords: رقیق کننده ارگانیک; BA; bile acid(s); Asbt; apical sodium-dependent bile acid transporter; Ost; organic solute transporter; FXR; farnesoid X receptor; FGF15; fibroblast growth factor 15; Cyp7a1; cholesterol 7α-hydroxylase; FGFR4; fibroblast growth factor receptor 4; CA; cho
Getting the mOST from OST: Role of organic solute transporter, OSTα-OSTβ, in bile acid and steroid metabolism
Keywords: رقیق کننده ارگانیک; ABC; ATP-binding cassette; ASBT; apical sodium-dependent bile acid transporter; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone-3-sulfate; ER; endoplasmic reticulum; Endo H; endoglycosidase H; FGF; fibroblast growth factor; FGFR; fibroblast gr
A New Mechanism for Bile Acid Diarrhea: Defective Feedback Inhibition of Bile Acid Biosynthesis
Keywords: رقیق کننده ارگانیک; ASBT; apical sodium-dependent bile acid transporter; BA; bile acid; BAM; bile acid malabsorption; C4; 7α-hydroxy-4-cholesten-3-one; CYP7A1; cholesterol 7α hydroxylase; ELISA; enzyme-linked immunosorbent assay; FGFR4; fibroblast growth receptor 4; FGF15;