NADPH-cytochrome P450 reductase-mediated denitration reaction of 2,4,6-trinitrotoluene to yield nitrite in mammals
Keywords: OYE, old yellow enzyme; P450R, NADPH-cytochrome P450 reductase; iNOS, inducible nitric oxide synthase; TNT, 2,4,6-trinitrotoluene; 2-HADNT, 2-hydroxyamino-4,6-dinitrotoluene; 4-HADNT, 4-hydroxyamino-2,6-dinitrotoluene; 4,4’-AZT, 2,2’,6,6’-tetranitro-4,4’-