Keywords: Single molecule fluorescence imaging; Protein tracking; P2X1; 5HT3; Fluorescence; LGIC; Ligand-gated ion channel; GPCR G-protein coupled receptor; Molecular machine; Stochastic;
مقالات ISI (ترجمه نشده)
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New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors
Keywords: Antiplatelet therapy; Antithrombotics; Adenosine diphosphate; Cardiovascular disease; Acute coronary syndromes; P2Y1; P2Y12; P2X1; Dinucleoside polyphosphates; Bis-nucleoside polyphosphates; Inhibitors; PlateletsAp4A, P1,P4-di(adenosine-5′) tetraphosphate
A fluorescent approach for identifying P2X1 ligands
Keywords: Fluorescent; Ligand binding; Ligand gated ion channel; P2X1; Fragment-based drug discovery; Pharmacology; NF449; Alexa-647; FBDD; Fragment-based drug design; ATP; Adenosine triphosphate; SCA; Scaffold classification approach;
Mechanisms of allergy and clinical immunologyRhoA signaling through platelet P2Y1 receptor controls leukocyte recruitment in allergic mice
Keywords: Platelets; P2Y1; P2Y12; P2X1; allergic inflammation; RhoA; ADP; Adenosine diphosphate; IC50; Inhibitory concentration of 50%; Kd; Dissociation constant; MDC; Macrophage-derived chemokine; OVA; Ovalbumin; PGE1; Prostaglandin E1; PMN; Polymorphonuclear cell
The purinergic component of human bladder smooth muscle cells' proliferation and contraction under physiological stretch
Keywords: Bladder smooth muscle cell; Stretch; Proliferation; Contractility; P2X1; P2X2;
Methylprednisolone treatment delays remote cell death after focal brain lesion
Keywords: glucocorticoids; inferior olive; pontine nuclei; glia; inflammation; remote degeneration; CTRL; control rats; DAPI; 4,6-diamidino-2-phenylindole; HCb; hemicerebellectomy; IL-1β; interleukin-1 beta; IO; inferior olive; MPSS; methylprednisolone sodium succ
Apical P2XR contribute to [Ca2+]i signaling and Isc in mouse renal MCD
Keywords: P2X1; P2X4; Calcium signaling; Short circuit current; IMCD; OMCD; Renal ion transport; Kidney; Microperfusion;
Characterization of functional P2X1 receptors in mouse megakaryocytes
Keywords: αβ-meATP; α,β-methylene ATP; βγ-meATP; β,γ-methylene ATP; EGTA; ethylene glycol bis(β-aminoethylether)-N,N,Nâ²,Nâ²-tetraacetic acid; ES; external solution; IS; internal solution; NF023; 8,8â²-(carbonylbis(imino-3,1-phenylene carbonylimino)bis(
The platelet P2 receptors in arterial thrombosis
Keywords: Haemostasis; Thrombosis; ADP; ATP; P2Y1; P2Y12; P2X1; Antiplatelet drugs; Clopidogrel