Keywords: Cyclooxygenase; Metastasis; P2Y12; Phosphodiesterases; Platelets; Platelet-therapy;
مقالات ISI (ترجمه نشده)
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Keywords: Médicaments antiplaquettaires; Clopidogrel; Prasugrel; Aspirine; Ticagrelor; Transfusion plaquettaire; Hémorragie; Antidote; P2Y12; Antiplatelet agents; Clopidogrel; Prasugrel; Aspirine; Ticagrelor; Platelet transfusion; Bleeding; Antidote; P2Y12;
Keywords: CD39; M1/M2 microglia; Motoneuron; Oligodendrocyte; P2X7; P2Y12; ALS; amyotrophic lateral sclerosis; BBG; Brilliant Blue G; BDNF; brain-derived neurotrophic factor; BzATP; 2â²-3â²-O-(benzoyl-benzoyl) ATP; fALS; familial ALS; FUS; fused in sarcoma; HuR
Ticagrelor, a P2Y12 antagonist, attenuates vascular dysfunction and inhibits atherogenesis in apolipoprotein-E-deficient mice
Keywords: Atherosclerosis; Inflammation; Endothelial function; P2Y12; Ticagrelor; Ach; acetylcholine; ACS; acute coronary syndrome; ADP; adenosine diphosphate; apoEâ/â; apolipoprotein E-deficient; Ctrl; control; HUVEC; human umbilical vein endothelial cell; ICA
Preparation and characterization of solid dispersion of novel dual antiplatelet agent BF061 for oral use
Keywords: Antiplatelet agent; P2Y12; Solid dispersion; BF061;
Ticagrelor Removal From Human Blood
Keywords: concentration; drug; P2Y12; platelet; removal; sorbent; ticagrelor; b.i.d.; twice a day; BSA; bovine serum albumin; CABG; coronary artery bypass graft;
Knockout of P2Y12 aggravates experimental autoimmune encephalomyelitis in mice via increasing of IL-23 production and Th17 cell differentiation by dendritic cells
Keywords: EAE; DC; P2Y12; Knockout; Th17; IL-23;
New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors
Keywords: Antiplatelet therapy; Antithrombotics; Adenosine diphosphate; Cardiovascular disease; Acute coronary syndromes; P2Y1; P2Y12; P2X1; Dinucleoside polyphosphates; Bis-nucleoside polyphosphates; Inhibitors; PlateletsAp4A, P1,P4-di(adenosine-5′) tetraphosphate
C-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets
Keywords: Platelets; P2Y12; Lipid rafts; Signal transduction; Platelet activation
Mechanisms of allergy and clinical immunologyRhoA signaling through platelet P2Y1 receptor controls leukocyte recruitment in allergic mice
Keywords: Platelets; P2Y1; P2Y12; P2X1; allergic inflammation; RhoA; ADP; Adenosine diphosphate; IC50; Inhibitory concentration of 50%; Kd; Dissociation constant; MDC; Macrophage-derived chemokine; OVA; Ovalbumin; PGE1; Prostaglandin E1; PMN; Polymorphonuclear cell
Adenosine-Mediated Effects of Ticagrelor: Evidence and Potential Clinical Relevance
Keywords: acute coronary syndrome(s); adenosine; antiplatelet agents; P2Y12; ticagrelor; ACS; acute coronary syndrome(s); ADP; adenosine diphosphate; cAMP; cyclic adenosine monophosphate; CNT; concentrative nucleoside transporter; ENT1; equilibrative nucleoside tr
Effect of P2Y1 and P2Y12 genetic polymorphisms on the ADP-induced platelet aggregation in a Korean population
Keywords: P2Y1; P2Y12; Polymorphism; ADP; Platelet aggregation;
Comparison of Antiplatelet Efficacy and Tolerability of Clopidogrel Napadisilate With Clopidogrel Bisulfate in Coronary Artery Disease Patients After Percutaneous Coronary Intervention: A Prospective, Multicenter, Randomized, Open-Label, Phase IV, Noninfe
Keywords: active-control equivalence trial; antiplatelet efficacy; clopidogrel bisulfate; clopidogrel napadisilate; P2Y12; tolerability;
Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: Effects on clopidogrel response
Keywords: Clopidogrel; CYP2C19; Gene polymorphisms; MDR1; P2Y12
Effect of clopidogrel on circulating biomarkers of angiogenesis and endothelial activation
Keywords: Angiogenic factors; Endothelial activation; Clopidogrel; Platelet; P2Y12
A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor
Keywords: P2Y12; Platelet activation; Thrombosis; Acute coronary syndrome; Piperazinyl-pyridines
Identification of P2Y12 single-nucleotide polymorphisms and their influences on the variation in ADP-induced platelet aggregation
Keywords: ADP; Adenosine diphosphate; SNP; single-nucleotide polymorphism; PCR; polymerase chain reaction; 5'-UTR; 5â²-untranslated regions; htSNPs; haplotype-tagging SNPs; LD; linkage disequilibrium; Aggregation; Haplotype; Linkage Disequilibrium; P2Y12; Platel
La thrombose de stent, de plus en plus rare !
Keywords: Thrombose de stent; Agrégation plaquettaire; P2Y12; Stent thrombosis; Platelet aggregation; P2Y12 receptor;
Prediction of P2Y12 antagonists using a novel genetic algorithm-support vector machine coupled approach
Keywords: P2Y12; Genetic algorithm; Support vector machine; Descriptor selection
Composition of thrombi in late drug-eluting stent thrombosis versus de novo acute myocardial infarction
Keywords: AMI; acute myocardial infarction; BMS; bare metal stent; DES; drug-eluting stent; GP; glycoprotein; TF; tissue factor; VWF; von Willebrand factor; DES thrombosis; Platelet; Fibrin; P2Y12;
Enhanced platelet reactivity and thrombosis in Apoe-/- mice exposed to cigarette smoke is attenuated by P2Y12 antagonism
Keywords: Apoe; Cigarette smoking; Thrombosis; P2Y12
Mutational analysis of residues important for ligand interaction with the human P2Y12 receptor
Keywords: P2Y12; cyclic AMP; site-directed mutation;
Purinergic receptor-mediated morphological changes in microglia are transient and independent from inflammatory cytokine release
Keywords: LPS; ATP; TNFα; Purinergics; P2Y12; Microglia activation; 2-Methylthio ADP
Thienopyrimidine-based P2Y12 platelet aggregation inhibitors
Keywords: P2Y12; Thienopyrimidine; Platelet aggregation inhibition
Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis
Keywords: AZD6140; Ticagrelor; P2Y12; Thienopyridine; Platelet aggregation; Bleeding
Contribution of P2Y1 receptors to ADP signalling in mouse spinal cord cultures
Keywords: P2Y1; P2Y12; P2Y13; Spinal cord; Calcium; Phosphorylation; Neurons; Glia; ADP;
Platelet PAR1 receptor density-Correlation to platelet activation response and changes in exposure after platelet activation
Keywords: ADP; Adenosine diphosphate; CRP; Collagen-related peptide, sequence GCO-(GPO)10-GCOG-NH2, where O is hydroxyproline; EDTA; Ethylenediaminetetraacetic acid; FITC; Fluorescein; GPIbα; Glycoprotein Ibα; MPV; Mean platelet volume; MRS2179; Antagonist to the
A Rose by Any Other Name? The Potential Consequences of Microglial Heterogeneity During CNS Health and Disease
Keywords: neuroinflammation; TREM; microglia; Alzheimer's disease; multiple sclerosis; purinergic receptors; P2Y12;
Molecular modeling of purinergic receptor P2Y12 and interaction with its antagonists
Keywords: P2Y12; ADP receptor; Antagonists; ATP; Platelets aggregation
Association between platelet P2Y12 haplotype and risk of cardiovascular events in chronic coronary disease
Keywords: P2Y12; Risk factor; Cardiovascular events; Platelet polymorphism;
The platelet P2 receptors in arterial thrombosis
Keywords: Haemostasis; Thrombosis; ADP; ATP; P2Y1; P2Y12; P2X1; Antiplatelet drugs; Clopidogrel