دانلود مقالات ISI درباره Pam, Positive Allosteric Modulator + ترجمه فارسی

Dissection of N,N-diethyl-N′-phenylpiperazines as α7 nicotinic receptor silent agonists

Keywords: ACh, acetylcholine; AcOH, acetic acid; DiEPP, N,N-diethyl-N′-phenylpiperazinium; DiMPP, N,N-dimethyl-N′-phenylpiperazinium; PAM, positive allosteric modulator; PEP, N-phenyl-N′ethylpiperazine; nAChR, nicotinic acetylcholine receptor; TFAA, trifluoroacetic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Elimination of a cholecystokinin receptor agonist ‘trigger’ in an effort to develop positive allosteric modulators without intrinsic agonist activity

Keywords: BDZ, benzodiazepine; CCK, cholecystokinin; CCK1R, type 1 cholecystokinin receptor; PAM, positive allosteric modulator; TM, transmembraneCholecystokinin; CCK1R; G protein-coupled receptors; Positive allosteric modulator; Obesity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies

Keywords: ACh, acetylcholine; nAChRs, neuronal nicotinic acetylcholine receptors; PAM, positive allosteric modulator; NAM, negative allosteric modulatorAllosteric modulation; animal behavioral studies; cognition; nicotinic acetylcholine receptor; pain; positive all

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Allosteric modulators of the α4β2 subtype of neuronal nicotinic acetylcholine receptors

Keywords: ACh, acetylcholine; nAChRs, neuronal nicotinic acetylcholine receptors; dFBr, desformylflustrabromine; PAM, positive allosteric modulator; NAM, negative allosteric modulator; 17-BE, 17-β-EstradiolNicotinic acetylcholine receptor; Allosteric modulation; Po

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Development and SAR of functionally selective allosteric modulators of GABAA receptors

Keywords: GABA, γ-aminobutyric acid; CNS, central nervous system; PAM, positive allosteric modulator; αx-GABAAR, αx-containing GABAA receptor; NAM, negative allosteric modulator; NA, neutral antagonist; SAR, structure–activity relationships; BZ, benzodiazepine; DZ,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

α3* and α7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells

Keywords: PAM, positive allosteric modulator; nAChR, nicotinic acetylcholine receptor; CICR, Ca2+-induced Ca2+ release; Mec, mecamylamine; MLA, methyllycaconitine; CPA, cyclopiazonic acidCa2+ signaling; IMR-32 neuroblastoma; Nicotinic acetylcholine receptor; α3; α7

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Metabotropic receptors for glutamate and GABA in pain

Keywords: mGluR, metabotropic glutamate receptor; GABA, γ-aminobutiric acid; GABA-B, metabotropic GABA receptor; GPCR, G-protein coupled receptors; NAM, negative allosteric modulator; PAM, positive allosteric modulator; DRG, dorsal root ganglia; PNS, peripheral ner

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Allosteric modulation of nicotinic acetylcholine receptors

Keywords: ACh, acetylcholine; nAChRs, neuronal nicotinic acetylcholine receptors; DMPP, dimethylphenylpiperazinium; 5-HI, 5-hydroxyindole; PAM, positive allosteric modulator; NAM, negative allosteric modulator; BSA, bovine serum albumine; LBD, ligand binding domain

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه