دانلود مقالات ISI درباره Pampa-Bbb + ترجمه فارسی

هیبرید های دونپزیل-فلاونوئیدی نوروژنیک و عصبی محافظت شده با سیگما-1 و مهار آنزیم های کلیدی در بیماری آلزایمر

Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease

Keywords: Donepezil-flavonoid hybrids; Neurogenesis; Neuroprotection; Sigma receptors; Human acetylcholinesterase; Human 5-lipoxygenase; Human monoamine oxidases; AChE; acetylcholinesterase; AD; Alzheimer's disease; ATCh; acetylthiocholine; BBB; blood-brain barrier

دانلود رایگان متن کامل مقاله ISI 81 صفحه سال انتشار : 2018 سفارش ترجمه

طراحی، سنتز و ارزیابی مشتقات جدید فنیل اسید-ال-آلکیلین به عنوان عوامل چند منظوره بالقوه برای درمان بیماری آلزایمر

Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

Keywords: Alzheimer's disease; Ferulic acid-O-alkylamines derivatives; Multifunctional agents; Butyrylcholinesterase inhibition; Aβ aggregation; Antioxidant activity; Neuroprotective effects; BuChE; butyrylcholinesterase; AChE; acetylcholinesterase; Aβ; β-amyloi

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

تعیین سریع آزمایش و محاسبات لیپوپروتئین آنالوگ داروهای فنیل اتیلامین

Rapid experimental and computational determination of phenethylamine drug analogue lipophilicity

Keywords: MLP; Molecular lipophilic potential; PAMPA-BBB; Blood-brain barrier parallel artificial membrane permeability assay; Papp; Apparent permeability; PEA; Phenethylamine; Forensic; PAMPA; Partition coefficient; Apparent permeability; Phenethylamine; Analogue;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Three newly identified lipophilic flavonoids in Tanacetum parthenium supercritical fluid extract penetrating the Blood-Brain Barrier

Keywords: Tanacetum parthenium L; Methylated flavonoids; PAMPA-BBB; NMR; Supercritical fluid extraction;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

Keywords: PTPRZ1; CNS disorders; Drug addiction; Molecular dynamics; Synthesis; EDCI; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide; HOBt; hydroxybenzotriazole; MCPBA; meta-chloroperbenzoic acid; MK; Midkine; PAMPA-BBB; membrane permeability assay for the blood-bra

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease

Keywords: AD; Alzheimer's disease; AChEIs; acetylcholinesterase inhibitors; NMDA; N-methyl-d-aspartate; Aβ; β-amyloid; τ; tau protein; ACh; acetylcholine; MTDLs; multi-target-directed ligands; MAO-B; monoamine oxidase B; MAO-A; monoamine oxidase A; BuChE; buty

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

BBB penetration-targeting physicochemical lead selection: Ecdysteroids as chemo-sensitizers against CNS tumors

Keywords: PAMPA-BBB; Physicochemical profiling; Lead selection; Ecdysteroid; Cancer; Adjuvant; Chemo-sensitization;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and evaluation of novel ferulic acid-memoquin hybrids as potential multifunctional agents for the treatment of Alzheimer's disease

Keywords: AD; Alzheimer's disease; AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; Aβ; β-amyloid peptide; BBB; blood-brain barrier; ACh; acetylcholine; MTDL; multitarget-directed ligand; EeAChE; electric eel AChE; CAS; catalytic anionic site; PAS; p

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه