دانلود مقالات ISI درباره Pampa + ترجمه فارسی

17β-carboxamide steroids – in vitro prediction of human skin permeability and retention using PAMPA technique

Keywords: Soft corticosteroids; PAMPA; Human skin permeability and retention; Quantitative structure–property relationship

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Afforestation effects on vegetation structure and diversity of grasslands in southern Brazil: The first years

Keywords: Eucalyptus; Grazing; Livestock; Management; Pampa;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Lamivudine permeability study: A comparison between PAMPA, ex vivo and in situ Single-Pass Intestinal Perfusion (SPIP) in rat jejunum

Keywords: Permeability; Lamivudine; PAMPA; In situ perfusion; Franz cell; Jejunum ex vivo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Predicting the exposure and antibacterial activity of fluoroquinolones based on physicochemical properties

Keywords: Protonation microconstants; True partition coefficients; Fluoroquinolones; PAMPA; Antimicrobial activity; MIC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Skin–PAMPA: A new method for fast prediction of skin penetration

Keywords: Skin permeability; PAMPA; In vitro high-throughput model; Transdermal drug penetration; Artificial membrane permeability assayUWL, unstirred water layer – thin stagnant layer adjacent to the surface of a membrane; in combo, methodology where a measured pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The exploitation of RHEIDAE in Pampa and Patagonia (Argentina) as recorded by chroniclers, naturalists and voyagers

Keywords: Rheids; Hunter-gatherers; Written sources; Archaeological record; Pampa; Patagonia;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

In situ artificial membrane permeation assay under hydrodynamic control: Correlation between drug in vitro permeability and fraction absorbed in humans

Keywords: In situ permeation; Stirring; PAMPA; Drug absorption; Paracellular transport; Unstirred water layer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists

Keywords: ABTS; 2,2′-azino-di-(3-ethylbenzthiazoline-6-sulfonic acid); AUC; area under the curve; BSA; bovine serum albumin; CRD; carbohydrate recognition domain; D; distribution coefficient; DCM; dichloromethane; DMSO; dimethyl sulfoxide; GIT; gastrointestinal t

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability

Keywords: Permeability; Solubility; PAMPA; Caco-2; Efflux ratio; Log BB; Blood–brain barrier

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones

Keywords: Malaria; Quinolones; Plasmodium; Synthesis; TDR; special programme for research and training in tropical diseases; CQ-R; chloroquine-resistant; CQ-S; chloroquine-sensitive; MDR; multi-drug-resistant; PAMPA; parallel artificial membrane permeability assay;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters

Keywords: Permeability; Solubility; PAMPA; Caco-2; Efflux-ratio; LogBB; Blood–brain barrier; Plasma protein binding

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and structure–activity relationships of oxamyl dipeptide caspase inhibitors developed for the treatment of liver disease

Keywords: Caspase; Apoptosis; Liver; Jurkat; α-Fas; Permeability; PAMPA; Oxamyl dipeptide

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Access to land, livestock production and ecosystem conservation in the Brazilian Campos biome: The natural grasslands dilemma

Keywords: Pampa; Stocking rate; Natural grasslands; Animal production; Land policies; Brazil

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Dihydroxy-pyrimidine and N-methylpyrimidone HIV-integrase inhibitors: Improving cell based activity by the quaternarization of a chiral center

Keywords: HIV-1 integrase; Pyrimidines; N-Methylpyrimidones; PAMPA

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

The usefulness of an artificial membrane accumulation index for estimation of the bioconcentration factor of organophosphorus pesticides

Keywords: PAMPA; Accumulation; Bioconcentration factor; Structure-property relationships; Organophosphorus pesticide;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Transport evaluation of salicylic acid and structurally related compounds across Caco-2 cell monolayers and artificial PAMPA membranes

Keywords: Caco-2; PAMPA; Transport mechanisms; Anionic compounds; pH-dependency

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

The PAMPA technique as a HTS tool for partition coefficients determination in different solvent/water systems

Keywords: PAMPA; Lipophilicity; 1,2-Dichloroethane; o-Nitrophenyl octyl ether

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones

Keywords: Flavonoids; Caco-2 model; PAMPA; Intestinal absorption; Permeability; Ionisation constants

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Passive oral drug absorption can be predicted more reliably by experimental than computational models—Fact or myth

Keywords: Intestinal absorption; Pharmacokinetics; Oral administration; Caco-2 cells; Cell line; Computer simulation; QSPR modelling; PAMPA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

Keywords: Unstirred water layer; Permeation; Cyclodextrin; PAMPA

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Novel generic UPLC/MS/MS method for high throughput analysis applied to permeability assessment in early Drug Discovery

Keywords: UPLC; UPLC/MS/MS; MRM; Quanoptimize; PAMPA; Permeability; High throughput

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Is PAMPA a useful tool for discovery?

Keywords: oral absorption; permeability; passive diffusion; absorption potential; parallel artificial membrane permeability assay; PAMPA; in vitro models; log D; drug‐like properties;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Passive diffusion of polymeric surfactants across lipid bilayers

Keywords: Self-assembling polymeric micelles; mmePEG750P(CL-co-TMC); PAMPA; Liposomes; Diffusion

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Evaluation of in vitro brain penetration: Optimized PAMPA and MDCKII-MDR1 assay comparison

Keywords: BBB permeability screening; PAMPA; MDCKII-MDR1; High throughput screening; UPLC/MS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

QSAR study on permeability of hydrophobic compounds with artificial membranes

Keywords: PAMPA; Unstirred water layer; Membrane retention; Structure–property relationships; Bilinear model

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

PAMPA-critical factors for better predictions of absorption

Keywords: permeability; PAMPA; PAMPA‐BBB; oral absorption; human jejunal permeability; structure‐property relationships; in vivo/in vitro correlations; octanol-water log P; Caco‐2;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

PAMPA—A drug absorption in vitro model : 13. Chemical selectivity due to membrane hydrogen bonding: In combo comparisons of HDM-, DOPC-, and DS-PAMPA models

Keywords: PAMPA; Flux-pKa; Double-Sink; Hexadecane; DOPC; Oral absorption; Permeability

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Ion pair-mediated transport of metoprolol across a three lipid-component PAMPA system

Keywords: PAMPA; Permeability; Ion pair; Metoprolol; Fluidity; Membrane transport

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Lipid composition effect on permeability across PAMPA

Keywords: PAMPA; Transport; Lipid; Permeability; Fluidity; Ion pair

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Drug permeability across a phospholipid vesicle based barrier: A novel approach for studying passive diffusion

Keywords: Artificial membrane; Prediction; Oral absorption; PAMPA; Caco-2 model; Immobilized liposome chromatography (ILC); PSA; Passive diffusion; Permeability classification; Liposome; Intestinal absorption; Phospholipid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Soil springtails (Hexapoda: Collembola), symphylans and pauropods (Arthropoda: Myriapoda) under different management systems in agroecosystems of the subhumid Pampa (Argentina)

Keywords: Agroecosystems; Management systems; Collembolans; Symphylans; Pauropods; Soil; Pampa; Argentina

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Validation of the 96 well Caco-2 cell culture model for high throughput permeability assessment of discovery compounds

Keywords: ADME; absorption, distribution, metabolism, elimination; BCS; biopharmaceutics classification system; BMS; Bristol-Myers Squibb Company; HBSS; Hank's balanced salt solution; HEPES; N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid; IAM; immobilized ar

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

A novel high-throughput automated chip-based nanoelectrospray tandem mass spectrometric method for PAMPA sample analysis

Keywords: ADME; absorption, distribution, metabolism, elimination; DMSO; di-methyl sulphoxide; IAM; immobilized artificial membrane; LC/MS; liquid chromatography/mass spectrometry; HPLC; high pressure liquid chromatography; MDCK; mardin darby canine kidney cells; N

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay

Keywords: A to B; apical to basolateral; ADME; absorption, distribution, metabolism, elimination; B to A; basolateral to apical; BCRP; breast cancer resistance protein; HBSS; Hank's balanced salt solution; HEPES; N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Relationships between structure and high-throughput screening permeability of diverse drugs with artificial membranes: Application to prediction of Caco-2 cell permeability

Keywords: PAMPA; Artificial membrane permeability; Caco-2; Structure–property relationships

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pKaflux method

Keywords: PAMPA; Caco-2; Permeability; Aqueous boundary layer; Oral absorption;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه