Keywords: Calcium; Allergens; Gingival epithelial cells; Inflammation; PAR-2
مقالات ISI (ترجمه نشده)
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Keywords: calcium; PAR-2; rosacea; skin barrier function; tranexamic acid
Keywords: PAR-2; Oral mucosa; Squamous cell carcinoma; Carcinoma in situ; Cell proliferation; Cell invasion
Keywords: Asthma; epithelium; dendritic cells; TH2; AAM; Alternatively activated macrophage; BEC; Bronchial epithelial cell; cDC; Conventional dendritic cell; DC; Dendritic cell; FCP; Fibrinogen cleavage product; HDM; House dust mite; HM-GB1; High-mobility group bo
Keywords: Bladder; Bowel; Mast cell; PAR-2; Cross-sensitization; Trinitrobenzene sulfonic acid; Compound 48/80; Afferent nerves;
Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells
Keywords: G-protein coupled receptors; Interleukin-1β; C-Jun N-terminal kinase; Purinergic receptors; Inflammation; YM-254890 (PubChem CID: 9919454); H-89 (PubChem CID: 449241); NF340 (PubChem CID: 73755007); MRS2179 (PubChem CID: 24867852); ZM241385 (PubChem CID:
TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections
Keywords: TMPRSS2; Influenza virus; Coronavirus; Therapeutics; ARE; androgen receptor element; AEBSF; 4-(2-Aminomethyl)benzenesulfonyl fluoride hydrochloride; BHH; Bromhexine hydrochloride; CoV; coronavirus; DESC1; serine protease DESC1; EST; (2S,3S)-trans-Epoxysuc
Per a 10 activates human derived epithelial cell line in a protease dependent manner via PAR-2
Keywords: AEBSF-4; benzenesulfonyl fluoride hydrochloride; BSA; bovine serum albumin; FBS; fetal bovine serum; GMCSF; granulocyte macrophage colony-stimulating factor; PAR; protease activated receptor; Airway epithelium; Ca2+ mobilization; PAR-2; Proinflammatory cy
Protease-activated receptor 2 enhances renal cell carcinoma cell invasion and migration via PI3K/AKT signaling pathway
Keywords: PAR-2; Renal cell carcinoma; Invasion; PI3K/AKT pathway; MMP-13; uPA;
Proteinase-activated receptor 2 blockade impairs CCL11- or allergen-induced eosinophil recruitment in experimental pleurisy
Keywords: Eosinophil; Eosinophil migration; CCL11; Proteinase-activated receptor-2; PAR-2
Anti-inflammatory actions of Chemoattractant Receptor-homologous molecule expressed on Th2 by the antagonist MK-7246 in a novel rat model of Alternaria alternata elicited pulmonary inflammation
Keywords: A. alternata; Alternaria alternata; OVA; Ovalbumin; Th2; Type 2 helper cells; CRTH2; Chemoattractant Receptor-homologous molecule expressed on Th2 cells; MK-7246; {(7R)-7-[[(4-fluorophenyl)sulfonyl](methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl
The spinal inhibition of N-type voltage-gated calcium channels selectively prevents scratching behavior in mice
Keywords: ANOVA; analysis of variance; EDTA; ethylenediaminetetraacetic acid; GRP; gastrin-releasing peptide; GRPR; gastrin-releasing peptide receptor; i.d.; intradermal; i.t.; intrathecal; MPO; myeloperoxidase; PAR-2; proteinase-activated receptor 2; PBS; phosphat
Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations
Keywords: Alternaria alternata; allergic airway disease; asthma exacerbation; protease; IL-33; AEBSF; 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride; ALT; Alternaria; BALF; BAL fluid; CAT; Cat dander; HDM; House dust mite; MCPT-1; Mast cell protease-1; MMP-
Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling
Keywords: RA; rheumatoid arthritis; FLS; fibroblast-like synoviocytes; ACPA; anti-citrullinated peptide antibody; DKK1; dickkopf-1; 11β-HSD1; 11beta-hydroxysteroid dehydrogenase type 1; PADI4; peptidylarginine deiminase-4; hTERT; human telomerase reverse transcrip
Protease-activated receptor-2 induces proinflammatory cytokine and chemokine gene expression in canine keratinocytes
Keywords: PAR-2; Dog; Skin; Atopic dermatitis; Inflammation
Prurito
Keywords: Prurito; Piel; Neuromediador; Nervio; Histamina; PAR-2;
Pseudopodial and β-arrestin-interacting proteomes from migrating breast cancer cells upon PAR2 activation
Keywords: PAR-2; Pseudopodium; Beta-arrestin; Cell migration; Proteomics
Quoi de neuf sur le prurit ?
Keywords: Prurit; Histamine; PAR-2; Allergie; NeuronePruritus; Histamine; Neuron; PAR-2; Allergy; Drugs
Cow's Milk Challenge Increases Weakly Acidic Reflux in Children with Cow's Milk Allergy and Gastroesophageal Reflux Disease
Keywords: AAF; Amino acid-based formula; CM; Cow's milk; CMA; Cow's milk allergy; GER; Gastroesophageal reflux; GERD; Gastroesophageal reflux disease; MII; Multichannel intraluminal impedance; PAR-2; Proteinase activated receptor 2; SAP; Symptom association p
The down regulation of neutrophil oxidative metabolism by S100A8 and S100A9: Implication of the protease-activated receptor-2
Keywords: Neutrophil (PMN); S100A8; S100A9; Calprotectin; PAR-2
PAR-2 triggers placenta-derived protease-induced altered VE-cadherin reorganization at endothelial junctions in preeclampsia
Keywords: PAR-2; VE-cadherin; Protease; Endothelium; Placenta; Preeclampsia;
Proteinase 3 carries small unusual carbohydrates and associates with αlpha-defensins
Keywords: PR3; Proteinase 3; NHP; human neutrophil peptide; WG; Wegener's granulomatosis; PMN; polymorphonuclear leukocytes; PAR-2; protease-activated receptor-2; IFN-γ; interferon gamma; ANCA; anti-neutrophil cytoplasmic antibodies; MPO; myeloperoxidase; SAP; ser
Activin-A is induced by interleukin-1β and tumor necrosis factor-α and enhances the mRNA expression of interleukin-6 and protease-activated receptor-2 and proliferation of stromal cells from endometrioma
Keywords: Endometriosis; activin-A; inflammatory cytokine; IL-6; PAR-2
Modulation of semaphorin 3A expression by calcium concentration and histamine in human keratinocytes and fibroblasts
Keywords: Semaphorin 3A; Nerve growth factor; Keratinocyte; Calcium concentration; Histamine; PAR-2
Inhibition of phosphatidylinositol-3 kinase γ reduces pruriceptive, inflammatory, and nociceptive responses induced by trypsin in mice
Keywords: Itch; AS605240; PI3Kγ; Trypsin; PAR-2; Mice;
Role of Ãarrestins in bradykinin B2 receptor-mediated signalling
Keywords: GPCRs; G protein-coupled receptors; ERK1/2; extracellular signal-regulated protein kinases; BK; bradykinin; B2R; bradykinin type 2 receptor; B2R-4A; B2R where 4 serine and threonine were mutated to alanines (Thr342/345, Ser346/348); GRK; G protein recepto
Trypsin Reduces Pancreatic Ductal Bicarbonate Secretion by Inhibiting CFTR Clâ Channels and Luminal Anion Exchangers
Keywords: Acinar Cells; Ductal Epithelium; Animal Model; Pancreatic Enzymes; BAPTA-AM; 1,2-bis(o-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid; CFTR; cystic fibrosis transmembrane conductance regulator Clâ channel; CFTRinh-172; CFTR inhibitor-172; [Ca2+]i; i
Tissue Factor–Factor VIIa complex induces cytokine expression in coronary artery smooth muscle cells
Keywords: Tissue Factor; FVIIa; PAR-2; Smooth muscle cells; Inflammation
Long-term downregulation of protease-activated receptor-2 expression in distal colon in rats following bacillary dysentery
Keywords: PAR-2; Colonic smooth muscle; Motility disorder;
Proteinase-activated receptor-2 mediated inhibition of TNFα-stimulated JNK activation - A novel paradigm for Gq/11 linked GPCRs
Keywords: PAR-2; proteinase-activated receptor-2; PAR-2 AP; PAR-2 activating peptide; 2f-LIGKV-OH; 2-furoyl-LIGKV-hydroxyl; JNK; c-jun N-terminal protein kinase; NFκB; nuclear factor kappa B; PKC; protein kinase C; MAP kinase; mitogen-activated protein kinase; PMA
Tryptase promotes human monocyte-derived macrophage foam cell formation by suppressing LXRα activation
Keywords: Tryptase; Macrophage; Foam cell; PAR-2; LXR;
Activation of microglial cells via protease-activated receptor 2 mediates neuronal cell death in cultured rat primary neuron
Keywords: PAR-2; Microglia; NO; ROS; TNF-α; MAPKs; NF-κB; Neuronal cell death
Intracolonical administration of protease-activated receptor-2 agonists produced visceral hyperalgesia by up-regulating serotonin in the colon of rats
Keywords: Visceral hyperalgesia; Protease-activated receptor (PAR); Serotonin; PAR-2; 5-HT; EC cell
Actinic cheilitis: Epithelial expression of COX-2 and its association with mast cell tryptase and PAR-2
Keywords: COX-2; PAR-2; Tryptase; Mast cells; Lip; Carcinogenesis
Immunoglobulin A with protease activity secreted in human milk activates PAR-2 receptors, of intestinal epithelial cells HT-29, and promotes beta-defensin-2 expression
Keywords: Human milk; Breastfeeding; sIgA; Defensin; Natural catalytic antibodies; PAR-2;
Increased expression of protease-activated receptor-2 in mucosal mast cells in Crohn's ileitis
Keywords: PAR-2; protease-activated receptor-2; HMC-1; human leukemia mast cell line; TNF-α; tumor necrosis factor-α; Crohn's ileitis; Mast cells; Protease-activated receptor-2; Tumor necrosis factor-α;
Potential role of protease-activated receptor-2-stimulated activation of cytosolic phospholipase A2 in intestinal myofibroblast proliferation: Implications for stricture formation in Crohn's disease
Keywords: Crohn's disease; Intestinal myofibroblasts; Phospholipase A2; Protease-activated receptor-2; Tumor necrosis factor-α; AA; arachidonic acid; AACOCF3; arachidonyl trifluoromethyl ketone; BEL; bromoenol lactone; CD; Crohn's disease; MAFP; methyl arachidonyl
Essential role of mitogen-activated protein kinase pathways in protease activated receptor 2-mediated nitric-oxide production from rat primary astrocytes
Keywords: Trypsin; PAR-2; NO; MAPKs; NF-κB; Astrocytes;
Protease-activated receptor-2 (PAR-2) in cervical cancer proliferation
Keywords: PAR-2; Trypsin; Cervical cancer and cellular proliferation
G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFκB serine 536 phosphorylation in human keratinocytes
Keywords: PAR-2; proteinase-activated receptor-2; PAR-2 AP; PAR-2 activating peptide; 2f-LIGKV-OH; 2-furoyl-LIGKV-hydroxyl; NFκB; nuclear factor kappa B; IKK; inhibitory kappa B kinase; PKC; protein kinase C; siRNA; small interfering ribonucleic acid; RNAi; ribonu
Potential role of mast cells in hamster cheek pouch carcinogenesis
Keywords: Mast cells; Tryptase; PAR-2; Hamster cheek pouch; BrdU; Carcinogenesis;
Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro
Keywords: PAR-2; Mucin; Airway; Secretion
Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw
Keywords: Trypsin; Inflammation; Edema; Nociception; PAR-2; (Mouse)
Acute Pancreatitis: Bench to the Bedside
Keywords: ERCP; endoscopic retrograde cholangiography; FAEE; fatty acid ethanol esters; FNA; fine needle aspiration; HSP; heat shock proteins; IAP; inhibitors of apoptosis; PAF; platelet-activating factor; PAR-2; proteinase-activated receptor-2; PARP; polyADP-ribos
Acute Pancreatitis: Bench to the Bedside
Keywords: ERCP; endoscopic retrograde cholangiography; FAEE; fatty acid ethanol esters; FNA; fine needle aspiration; HSP; heat shock proteins; IAP; inhibitors of apoptosis; PAF; platelet-activating factor; PAR-2; proteinase-activated receptor-2; PARP; polyADP-ribos
Tryptase activates PKB in inflammatory reaction in ECV304 cells
Keywords: Tryptase; PAR-2; PKB; NF-κB; Inflammation; Mast cell