Identification and Structural Characterization of the Precursor Conformation of the Prion Protein which Directly Initiates Misfolding and Oligomerization
Keywords: فرم تقریبا انعطاف پذیر; PrP; prion protein; PrPC; cellular PrP; PrPSc; scrapie PrP; HDX; hydrogen-deuterium exchange; moPrP; mouse PrP; PUF; partially unfolded form; CTD; C-terminal domain; dm CTD; double mutant variant of the C-terminal domain; wt; wild-type; DLS; dynamic lig