Keywords: مدل PBPK; MMT; Ferroalloy; PBPK model; Risk assessment; CAA 211(b); CAA112; Reference concentration (RfC); Manganese;
مقالات ISI مدل PBPK (ترجمه نشده)
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Keywords: مدل PBPK; Clinical pharmacokinetics; Creatinine; Drug interaction; PBPK model; Quantitative analysis; Renal transporter; Trimethoprim;
Keywords: مدل PBPK; Allotments; Biomonitoring; Exposure; PBPK model; Toxic elements;
Keywords: مدل PBPK; Acute inhalation toxicity; In vitro; In silico; Ex vivo; Quantitative structure-activity relationships (QSAR); Adverse outcome pathway; Aggregate exposure pathway; Dosimetry; Integrated approach to testing and assessment (IATA); Risk assessment; ADME; abs
Keywords: مدل PBPK; Aggregate exposure; Permethrin; PBPK model; Pyrethroid; Diet; Air and dust; DCCA;
Keywords: مدل PBPK; PBPK model; Multiscale model; In silico toxicity prediction;
Keywords: مدل PBPK; PBPK model; QSP; Tramadol; Horse; Analgesia;
Keywords: مدل PBPK; Stomach; Peristaltic waves; Drug release; Pharmacokinetics; PBPK model;
Keywords: مدل PBPK; PBPK model; Dose response; Bayesian simulation; Arsenic; Publicly available data;
Keywords: مدل PBPK; D4; octamethylcyclotetrasiloxane; D5; decamethylcyclopentasiloxane; EI; electron impact; LOQ; limit of quantification; PBPK model; physiologically based pharmacokinetic model; PCPs; personal care products; TD-GD-MS; thermal desorption gas chromatography m
Keywords: مدل PBPK; Chemical incident; Reverse dosimetry; Variability; Uncertainty; Acrylonitrile; PBPK model; Human biomonitoring;
Keywords: مدل PBPK; Monte Carlo simulation; PBPK model; PBTK model; Chloromethane; Organic solvent; Risk assessment; Assessment factor; Uncertainty factor; Safety factor;
Health risk assessment of trihalomethanes mixtures from daily water-related activities via multi-pathway exposure based on PBPK model
Keywords: مدل PBPK; Trihalomethanes; Mixture exposure; Multi-pathway exposure; PBPK model; Risk assessment;
A physiologically based pharmacokinetic model for valacyclovir established based on absolute expression quantity of hPEPT1 and its application
Keywords: مدل PBPK; Valacyclovir (PubChem CID: 60773); acyclovir (PubChem CID: 2022); PBPK model; Absolute expression quantity of transporter; Valacyclovir; in vivo pharmacokinetics; Oral absorption; hPEPT1;
Influence of different proton pump inhibitors on the pharmacokinetics of voriconazole
Keywords: مدل PBPK; Voriconazole; Proton pump inhibitors; PPI; PBPK model; Drug-drug interactions;
Prediction of time-integrated activity coefficients in PRRT using simulated dynamic PET and a pharmacokinetic model
Keywords: مدل PBPK; PBPK model; PRRT treatment planning; Dynamic PET; PET noise model;
A two-step model of TiO2 nanoparticle toxicity in human liver tissue
Keywords: مدل PBPK; PBPK model; Cell-response model; Cell cycle; TiO2 nanoparticles; Nanotoxicology;
Assessing multimedia/multipathway exposures to inorganic arsenic at population and individual level using MERLIN-Expo
Keywords: مدل PBPK; 2-FUN; EU project (Full-chain and UNcertainty approaches for assessing health risks in FUture eNvironmental scenarios); 4FUN; EU project (The FUture of FUlly integrated human exposure assessment of chemicals: Ensuring the long-term viability and technolog
Multimedia & PBPK modelling with MERLIN-Expo versus biomonitoring for assessing Pb exposure of pre-school children in a residential setting
Keywords: مدل PBPK; 2-FUN; EU project (Full-chain and UNcertainty approaches for assessing health risks in FUture eNvironmental scenarios); 4FUN; EU project (The FUture of FUlly integrated human exposure assessment of chemicals: Ensuring the long-term viability and technolog
Differences in Food Effects for 2 Weak Bases With Similar BCS Drug-Related Properties: What Is Happening in the Intestinal Lumen?
Keywords: مدل PBPK; PBPK model; supersaturation; food effect; biopharmaceutics; posaconazole; ketoconazole;
PBPK modeling of the cis- and trans-permethrin isomers and their major urinary metabolites in rats
Keywords: مدل PBPK; PBPK model; cis/trans-Permethrin; 3-Phenoxybenzoic acid; cis- and trans-3-(2,2 dichlorovinyl)-2,2-dimethyl-(1-cyclopropane) carboxylic acid; Bayesian calibration; Metabolites
Development of a PBPK model of thiocyanate in rats with an extrapolation to humans: A computational study to quantify the mechanism of action of thiocyanate kinetics in thyroid
Keywords: مدل PBPK; Thiocyanate; Bayesian; PBPK model; NIS; TPO; Thyroid
Evaluation of three physiologically based pharmacokinetic (PBPK) modeling tools for emergency risk assessment after acute dichloromethane exposure
Keywords: مدل PBPK; Dichloromethane; PBPK model; Acute exposure; Risk assessment; Intoxication; Poisoning;
Serum and tissue pharmacokinetics of silibinin after per os and i.v. administration to mice as a HP-β-CD lyophilized product
Keywords: مدل PBPK; Silibinin; HP-β-CD; Lyophilization; Serum/tissue pharmacokinetics; PBPK model
Using physiologically based pharmacokinetic models to estimate the health risk of mixtures of trihalomethanes from reclaimed water
Keywords: مدل PBPK; Reclaimed water; Trihalomethanes; Mixture exposure; Human risk assessment; PBPK model;
Evaporation of decamethylcyclopentasiloxane (D5) from selected cosmetic products: Implications for consumer exposure modeling
Keywords: مدل PBPK; BP; biphenyl; C&PCPs; cosmetics and personal care products; D5; decamethylcyclopentasiloxane; GC/FID; gas chromatography with flame ionization detector; HBSS; Hank's Balanced Salt Solution; HEPES; 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid; M4Q; t
Testing the coherence between occupational exposure limits for inhalation and their biological limit values with a generalized PBPK-model: The case of 2-propanol and acetone
Keywords: مدل PBPK; Coherence; Occupational exposure limits; Biological limit values; PBPK model; 2-Propanol; Acetone; Uncertainty; Variability;
A PBPK model to estimate PCDD/F levels in adipose tissue: Comparison with experimental values of residents near a hazardous waste incinerator
Keywords: مدل PBPK; PCDD/Fs; Adipose tissue; Temporal trend; Hazardous waste incinerator; PBPK model;
Nasal dosimetry of inspired naphthalene vapor in the male and female B6C3F1 mouse
Keywords: مدل PBPK; Naphthalene; Nose; Inhalation dosimetry; PBPK model;
Relative source allocation of TDI to drinking water for derivation of a criterion for chloroform: A Monte-Carlo and multi-exposure assessment
Keywords: مدل PBPK; PBPK model; Route-to-route extrapolation; Water quality standard; Risk assessment;
Predicting the absorption of chemical vapours
Keywords: مدل PBPK; Linear regression models; Predictive models; PBPK model; Organic solvents; Dermal to inhalation ratio; Dermal contribution ratio; DIR; DCR
Separating uncertainty and physiological variability in human PBPK modelling: The example of 2-propanol and its metabolite acetone
Keywords: مدل PBPK; Uncertainty; Variability; Nested Monte Carlo; PBPK model; 2-Propanol; Acetone
Kinetic modelling of in vitro cell-based assays to characterize non-specific bindings and ADME processes in a static and a perfused fluidic system
Keywords: مدل PBPK; Toxicokinetic model; ADME processes; Perfusion culture; In vitro–in vivo extrapolation; Non-specific adsorption; PBPK model
Evaluation and prediction of pharmacokinetics of PFOA and PFOS in the monkey and human using a PBPK model
Keywords: مدل PBPK; PFAAs; collectively refers to perfluoroalkyl acid carboxylates and sulfonates; PBPK model; physiologically based pharmacokinetic model; PFOA; perfluorooctanoate; PFOS; perfluorooctane sulfonate; Physiologically-based pharmacokinetic modeling; PBPK; Toxico
Generic parameterization for a pharmacokinetic model to predict Cd concentrations in several tissues of different fish species
Keywords: مدل PBPK; Fish metal bioaccumulation; Water and diet exposure; PBPK model; Generic parameterization
Acute inhalation of 2,2,4-trimethylpentane alters visual evoked potentials and signal detection behavior in rats
Keywords: مدل PBPK; Neurotoxicity; PBPK model; Volatile organic compound; Visual evoked potential; Behavior; Gasoline
A stochastic whole-body physiologically based pharmacokinetic model to assess the impact of inter-individual variability on tissue dosimetry over the human lifespan
Keywords: مدل PBPK; PBPK model; Children; Advanced age; Gestation; Inter-individual variability
Physiologically based pharmacokinetic model development and simulations for ethylene dichloride (1,2-dichloroethane) in rats
Keywords: مدل PBPK; Ethylene dichloride; PBPK model; Extrahepatic metabolism
PBPK models in risk assessment—A focus on chloroprene
Keywords: مدل PBPK; PBPK model; Chloroprene; Risk assessment; Toxicokinetic; IRIS
Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents: III. PBPK modeling of white spirit constituents as a tool for integrating animal and human test data
Keywords: مدل PBPK; Trimethyl benzene; n-Decane; White spirit; Toxicokinetics; PBPK model; Central nervous system effects; Occupational exposure limits; Cross-species extrapolation
Development of a physiologically based pharmacokinetic model for bisphenol A in pregnant mice
Keywords: مدل PBPK; Risk assessment; Bisphenol A; PBPK model; Offspring
Development of a rat dosimetry model for bromate
Keywords: مدل PBPK; PBPK model; Rat; Bromate; Bromide
Evaluation of antiangiogenic treatment effects on tumors' microcirculation by Bayesian physiological pharmacokinetic modeling and magnetic resonance imaging
Keywords: مدل PBPK; Tumor microcirculation; Bayesian analysis; PBPK model; Vistarem; Dynamic MRI
Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: A case study with toluene
Keywords: مدل PBPK; PBPK model; Child; CYP2E1; Interindividual variability
Estimated cancer risk of dioxins to humans using a bioassay and physiologically based pharmacokinetic model
Keywords: مدل PBPK; Dioxin; Risk assessment; Hepatic foci; PBPK model
Heavy incense burning in temples promotes exposure risk from airborne PMs and carcinogenic PAHs
Keywords: مدل PBPK; Temple; Incense burning; Particulate matters; Polycyclic aromatic hydrocarbons; HRT model; PBPK model; Risk assessment
Applications of dosimetry modeling to assessment of neurotoxic risk
Keywords: مدل PBPK; Haber's rule; Duration adjustments; PBPK model; Acute toxicity; Toluene; Trichloroethylene;
The development of a physiologically-based pharmacokinetic model using the distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the tissues of the eastern oyster (Crassostrea virginica)
Keywords: مدل PBPK; Crassostrea virginica; PBPK model; 2,3,7,8-Tetrachlorodibenzo-p-dioxin; Bioaccumulation;