
Blocking tumor cell eicosanoid synthesis by GPx4 impedes tumor growth and malignancy
Keywords: GPx4, glutathione peroxidase 4; COX(s), cyclooxygenase(s); LOX(s), lipoxygenase(s); PGE2, prostaglandin E2; DMEM, Dulbecco's modified Eagle's medium; PCOOH, phosphatidylcholine hydroperoxide; L929-GPx4 or B16BL6-GPx4, GPx4-overexpressing L929 or B16BL6 ce