دانلود مقالات ISI درباره Pd-L1 + ترجمه فارسی

PD-L1 Expression Heterogeneity in Non-Small Cell Lung Cancer: Defining Criteria for Harmonization between Biopsy Specimens and Whole Sections

Keywords: PD-L1; Lung; Cancer; Heterogeneity; Biopsies;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

A radiosensitivity gene signature and PD-L1 predict the clinical outcomes of patients with lower grade glioma in TCGA

Keywords: Glioma; Radiosensitivity; TCGA; PD-L1; Radiation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Nivolumab in advanced non-small-cell lung cancer patients who failed prior platinum-based chemotherapy

Keywords: AE; adverse event; ALK; anaplastic lymphoma kinase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CI; confidence interval; CR; complete response; ECOG; Eastern Cooperative Oncology Group; EGFR; epidermal growth factor receptor; HR; hazar

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Precise immune tolerance for hPSC derivatives in clinical application

Keywords: AAV; adeno-associated virus; ATIIC; lung alveolar epithelial type II cell; B2M; b-2-microglobulin; BAC; bacterial artificial chromosome; CIITA; class-II MHC trans-activator; CP hESC; hESC lines constitutively expressing CTLA4Ig and programmed death-ligand

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Perioperative Immunotherapy in Muscle-Invasive Bladder Cancer and Upper Tract Urothelial Carcinoma

Keywords: PD1; PD-L1; Muscle-invasive bladder cancer; Urothelial carcinoma; Renal pelvis urothelial carcinoma; Transitional cell carcinoma; Ureteral carcinoma;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Safety and clinical activity of atezolizumab monotherapy in metastatic non-small-cell lung cancer: final results from a phase I study

Keywords: Atezolizumab; Non-small-cell lung cancer; PD-L1; Immune checkpoint inhibitor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Tumor PD-L1 expression is associated with improved survival and lower recurrence risk in young women with oral cavity squamous cell carcinoma

Keywords: PD-L1; biomarkers; young patients; head and neck cancer; survival;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Pattern of programmed cell death-ligand 1 expression and CD8-positive T-cell infiltration before and after chemoradiotherapy in rectal cancer

Keywords: PD-L1; Immune checkpoint inhibitor; Immune stromal PD-L1; Rectal cancer; CD8; T cell; Chemoradiotherapy; Immunotherapy; Tumour-infiltrating lymphocyte; Synergistic effect;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

The role of immune microenvironment in small-cell lung cancer: Distribution of PD-L1 expression and prognostic role of FOXP3-positive tumour infiltrating lymphocytes

Keywords: Tumour-infiltrating lymphocytes (TILs); PD-L1; FOXP3; CD8; Prognostic marker; Immunotherapy; Immune checkpoint inhibitors;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

B7-H6 expression is induced by lipopolysaccharide and facilitates cancer invasion and metastasis in human gliomas

Keywords: Bax; Bcl-2 associated X protein; Bcl-2; B-cell lymphoma-2; CCK-8; Cell counting kit-8; DMEM; Dulbecco's modified Eagle's medium; EMT; Epithelial-mesenchymal transition; FBS; Fetal bovine serum; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; GM-CSF; Gran

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

The prognostic role of PD-L1 expression for survival in head and neck squamous cell carcinoma: A systematic review and meta-analysis

Keywords: Head and neck cancer; Squamous cell carcinoma; Programmed death-ligand 1; PD-L1; HPV; Tumor-infiltrating lymphocytes; TIL; Survival; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

L'immunohistochimie PD-L1 dans les cancers pulmonaires non à petites cellules, perspectives d'avenir

Keywords: cancer du poumon non à petites cellules; immunohistochimie; PD-L1; test diagnostic compagnon; test diagnostic complémentaire; complementary diagnostic test; companion diagnostic test; immunohistochemistry; non-small cell lung carcinoma; PD-L1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors

Keywords: Cancer immunotherapy; Immune checkpoint blockade; CTLA-4; PD-1; PD-L1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

KRAS-Mutant non-small cell lung cancer: From biology to therapy

Keywords: BATTLE; Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination; BET; bromodomains and extra-terminal domain; CDK; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CI; confidence interval; CUSTOM; Molecular Profiling and Targete

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Dual IFN-γ/hypoxia priming enhances immunosuppression of mesenchymal stromal cells through regulatory proteins and metabolic mechanisms

Keywords: Mesenchymal stromal cells; Immunosuppression; Priming; Metabolism; Hypoxia; Interferon gamma; MSC; mesenchymal stromal cell; IDO; indoleamine-2,3-dioxygenase; PD-L1; programmed death ligand 1; HLA; human leukocyte antigen;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Bacterially activated B-cells drive T cell differentiation towards Tr1 through PD-1/PD-L1 expression

Keywords: Hfstim; Helicobacter felis -stimulated; Hfstim- IL-10+ B; Helicobacter felis-stimulated IL-10- producing B cells; Hfstim- IL-10-B; Helicobacter felis-stimulated IL-10- nonproducing B cells; Breg; regulatory B cells; PD-1; programmed death 1; PD-L1; pr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Concern over cost of and access to cancer treatments: A meta-narrative review of nivolumab and pembrolizumab studies

Keywords: ASCO; American Society of Clinical Oncology; BRAF; B-raf proto-oncogene, serine/threonine kinase; CTLA4; cytotoxic T-lymphocyte associated protein 4; ESMO; European Society for Medical Oncology; FDA; Food and Drug Administration; ICER; incremental cost-ef

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Understanding the structural and energetic basis of PD-1 and monoclonal antibodies bound to PD-L1: A molecular modeling perspective

Keywords: PD-L1; PD-1; Monoclonal antibody; Molecular dynamics simulation; Virtual alanine scanning mutagenesis;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

The effect of IκK-16 on lipopolysaccharide-induced impaired monocytes

Keywords: DAMPs; danger-associated molecular patterns; ELISA; enzyme-linked immunosorbent assay; G-CSF; granulocyte-colony stimulating factor; GM-CSF; granulocyte-macrophage colony-stimulating factor; IFN-γ; interferon-gamma; IL-10; interleukin-10; IκK; inhibitor

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Case-control study of PD-1, PD-L1 and B7-H3 expression in lung cancer patients with and without human immunodeficiency virus (HIV) infection

Keywords: Human immunodeficiency virus; Lung cancer; PD-1; PD-L1; B7-H3;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Safety and Efficacy of PD-1 Inhibitors Among HIV-Positive Patients With Non-Small Cell Lung Cancer

Keywords: Lung cancer; HIV; Pembrolizumab; Nivolumab; PD-1; PD-L1; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients

Keywords: miR-125; miR-148; Antitumor Immune Response; Immune Checkpoints; CTL; cytotoxic T lymphocytes; CTLA-4; cytotoxic T lymphocyte associated protein 4; EAC; esophageal adenocarcinoma; gMFI; geometric mean fluorescence intensity; HLA-A/B/C; human leukocyte ant

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

PD-1/PD-L1 inhibitor screening of caffeoylquinic acid compounds using surface plasmon resonance spectroscopy

Keywords: PD-1; PD-L1; Surface plasmon resonance; Caffeoylquinic acid compounds; Small-molecule inhibitors;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors

Keywords: Immune Regulation; Tumor Immunosuppression; microRNA15A/16-1; Colon Cancer Model; AD; azoxymethane with dextran sodium sulfate; CAC; colitis-associated colorectal cancer; CRC; colorectal cancer; CXCL; chemokine (C-X-C motif) ligand; DSS; dextran sodium

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Loss of PD-L1 (SP-142) expression characterizes renal vein tumor thrombus microenvironment in clear cell renal cell carcinoma

Keywords: Clear cell renal cell carcinoma; Intratumor heterogeneity; Tumor thrombus; Immunotherapy; PD-L1; Tumor sampling;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 expression in tumor cells and the immunologic milieu of bladder carcinomas: a pathologic review of 165 cases

Keywords: Bladder cancer; Urothelial carcinoma; Transitional cell carcinoma; PD-L1; PD-1; Immune checkpoint inhibitors; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Prognostic Value of PD-L1 mRNA Sequencing Expression Profile in Non-Small Cell Lung Cancer

Keywords: CCLE; Cancer Cell Line Encyclopedia; GTEx; Genotype-Tissue Expression; HR; hazard ratio; IHC; immunohistochemical; NSCLC; non-small cell lung cancer; PD-1; programmed cell death protein one; PD-L1; programmed cell death protein ligand 1; OS; overall survi

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Monocyte Programmed Death Ligand-1, A Predicator for 28-Day Mortality in Septic Patients

Keywords: Sepsis; Mortality; PD-L1; Prognosis;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Immunomodulatory effects of BRAF and MEK inhibitors: Implications for Melanoma therapy

Keywords: Binimetinib (PubChem CID: 10288191); Cobimetinib (PubChem CID: 16222096); Dabrafenib (PubChem CID: 44462760); Encorafenib (PubChem CID: 50922675); Trametinib (PubChem CID: 11707110); Vemurafenib (PubChem CID: 42611257); ATC; adoptively transferred T cells

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of PD-L1 expression by matrix stiffness in lung cancer cells

Keywords: Actin; PD-L1; Immunotherapy; Lung cancer; Mechanotransduction; Tumor microenvironment;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?

Keywords: Cyclophosphamide (PubChem CID: 2907); DTIC (Dacarbazine) (PubChem CID: 5353562); GPI 15427 (PubChem CID: 11739525); Lomeguatrib (PubChem CID: 3025944); NU 1025 (PubChem CID: 63306); Temozolomide (PubChem CID: 5394); BER; base excision repair; CD2F1; hybri

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

BRAF Mutant Lung Cancer: Programmed Death Ligand 1 Expression, Tumor Mutational Burden, Microsatellite Instability Status, and Response to Immune Check-Point Inhibitors

Keywords: BRAF; lung cancer; PD-1; PD-L1; immune check-point inhibitors;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 Expression of Tumor Cells, Macrophages, and Immune Cells in Non-Small Cell Lung Cancer Patients with Malignant Pleural Effusion

Keywords: Malignant pleural effusion; Lung cancer; PD-L1; Tumor cell; Immune cell;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Correlations of PD-L1 gene polymorphisms with susceptibility and prognosis in hepatocellular carcinoma in a Chinese Han population

Keywords: HCC; Hepatocellular carcinoma; TACE; Transcatheter arterial chemoembolisation; FDA; Food and Drug Administration; OS; Overall survival; PD-1; Programmed dealth-1; PD-L1; Programmed dealth-1 ligand-1; NSCLC; Non-small cell lung cancer; SNPs; Single nucleot

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

HDAC inhibitors as epigenetic regulators for cancer immunotherapy

Keywords: AICD; activation-induced cell death; AML; acute myeloid leukemia; APC; antigen-presenting cells; CAR; coxsackie- and adenovirus receptor; CDKs; cyclin-dependent kinases; CG; cancer germline; DCs; dendritic cells; HAT; histone acetyltransferase; HDAC; hist

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Programmed death-1 ligands PD-L1 and PD-L2 show distinctive and restricted patterns of expression in lymphoma subtypes

Keywords: PD-L1; PD-L2; Immune checkpoint; Hodgkin lymphoma; Non-Hodgkin lymphoma;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells

Keywords: APC; antigen-presenting cell; BMDCs; bone marrow-derived dendritic cells; CFSE; carboxyfluorescein succinimidyl ester; CTL; cytotoxic T lymphocyte; CTLA-4; cytotoxic T lymphocyte-associated antigen-4; DCs; dendritic cells; ERK; extracellular-signal-regula

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Prognostic value of programmed death ligand 1, p53, and Ki-67 in patients with advanced-stage colorectal cancer

Keywords: Colorectal cancer; Prognosis; Biomarkers; PD-L1; p53; Ki-67 labeling index;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Clinical Features and Management of Acquired Resistance to PD-1 Axis Inhibitors in 26 Patients With Advanced Non-Small Cell Lung Cancer

Keywords: PD-1; PD-L1; acquired resistance; non-small cell lung cancer; immunotherapy;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells

Keywords: IL-6; Macrophages; CRPC; NK cell cytotoxicity; PD-L1; NKG2D;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

FOXOs in cancer immunity: Knowns and unknowns

Keywords: 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 testing using the clone 22C3 pharmDx kit for selection of patients with non-small cell lung cancer to receive immune checkpoint inhibitor therapy: are cytology cell blocks a viable option?

Keywords: Non-small cell lung cancer (NSCLC); Adenocarcinoma; PD-L1; Cytology cell block; Biopsy;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

FASN-TGF-β1-PD-L1 axis contributes to the development of resistance to NK cell cytotoxicity of cisplatin-resistant lung cancer cells

Keywords: Fatty acid synthase (FASN); Cisplatin-resistant lung cancer; PD-L1; NK cells; TGF-β1;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Patient-Reported Outcomes in OAK: A Phase III Study of Atezolizumab Versus Docetaxel in Advanced Non-Small-cell Lung Cancer

Keywords: Health-related quality of life; Immune checkpoint inhibitor; Immunotherapy; Patient-reported outcomes; PD-L1;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Rationale for combination of therapeutic antibodies targeting tumor cells and immune checkpoint receptors: Harnessing innate and adaptive immunity through IgG1 isotype immune effector stimulation

Keywords: ADCC; Cetuximab; CTLA-4; PD-L1; PD-1; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells

Keywords: Oral cancer; Thyroxine; PD-L1; Proliferation; NDAT;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Programmed Cell Death Ligand 1 Expression in Non-Small-cell Lung Cancer Patients With Interstitial Lung Disease: A Matched Case-control Study

Keywords: Checkpoint inhibitor; Immunohistochemical analysis; Interstitial pneumonia; Programmed cell death protein 1; PD-L1;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K pathway in prostate cancer: All resistant roads lead to PI3K

Keywords: CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Merkel cell carcinomas infiltrated with CD33+ myeloid cells and CD8+ T cells are associated with improved outcome

Keywords: CD33; immune infiltrate; macrophages; Merkel cell carcinoma; myeloid cells; PD-L1; AJCC; American Joint Committee on Cancer; CI; confidence interval; FFPE; formalin-fixed paraffin-embedded; HLA-DR; human leukocyte antigen-DR; HR; hazard ratio; MCC; Merk

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه