Keywords: PDC، پیرووات دهیدروژناز مجتمع; PDC, pyruvate dehydrogenase complex; PDH, pyruvate dehydrogenase; PDHA1, human gene that encodes α subunit of PDH; Pdha1, murine orthologue of PDHA1; wt, wild-type Pdha1 allele; flox8, Pdha1 floxed allele; Δex8, Pdha1 null allele; E18, embryonic day 18; P
مقالات ISI PDC، پیرووات دهیدروژناز مجتمع (ترجمه نشده)
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Complex genetic findings in a female patient with pyruvate dehydrogenase complex deficiency: Null mutations in the PDHX gene associated with unusual expression of the testis-specific PDHA2 gene in her somatic cells
Keywords: PDC، پیرووات دهیدروژناز مجتمع; PDC, pyruvate dehydrogenase complex; SDS-PAGE, sodium dodecyl sulfate - polyacrylamide gel electrophoresis; IEF, isoelectric focusing; IP, isoelectric point; qPCR, quantitative real time PCR; DMR, differentially methylated region; 5'RACE, rapid amplificat
A light–dark shift strategy derived from light-responded metabolic behaviors for polyketides production in marine fungus Halorosellinia sp.
Keywords: PDC، پیرووات دهیدروژناز مجتمع; F-6-P, fructose-6-phosphate; F-1,6-2P, fructose-1,6-bisphosphate; PEP, phosphoenolpyruvate; PFK, phosphofructokinase; PK, pyruvate kinase; PDC, pyruvate dehydrogenase complex; PDH, pyruvate dehydrogenase; CS, citrate synthase; ICDH, isocitrate dehydrogena
Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding
Keywords: PDC، پیرووات دهیدروژناز مجتمع; HFD, high fat diet; LFD, low fat diet; PDC, pyruvate dehydrogenase complex; PDK4, pyruvate dehydrogenase kinase 4; Rb, retinoblastoma; PPARα, peroxisome proliferator-activated receptor; PGC-1α, peroxisome proliferator-activated receptor gamma coactivator
B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis
Keywords: PDC، پیرووات دهیدروژناز مجتمع; AMA, anti-mitochondrial autoantibodies; CBD, common bile duct; Idd, insulin dependent diabetes; NK, natural killer; NOD, nonobese diabetes; PBC, primary biliary cirrhosis; PDC, pyruvate dehydrogenase complex; TGF-β, transforming growth factor-βB cells; Au
Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription
Keywords: PDC، پیرووات دهیدروژناز مجتمع; STAT, signal transducer and activator of transcription; GRIM-19, genes associated with retinoid-interferon-induced mortality-19; ETC, electron transport chain; PDC, pyruvate dehydrogenase complex; PBC, primary biliary cirrhosis; IL-3, interleukin-3; SOCS,
Characterization of interactions of dihydrolipoamide dehydrogenase with its binding protein in the human pyruvate dehydrogenase complex
Keywords: PDC، پیرووات دهیدروژناز مجتمع; h, human; WT, wild-type; PDC, pyruvate dehydrogenase complex; E1, pyruvate dehydrogenase; E2, dihydrolipoamide acetyltransferase; E3, dihydrolipoamide dehydrogenase; BP, E3-binding protein; L3S1 (di-domain), the lipoyl domain (L3); first hinge region, E3-
Somatic mosaicism for PDHA1 mutation in a male with pyruvate dehydrogenase complex deficiency
Keywords: PDC، پیرووات دهیدروژناز مجتمع; PDH, pyruvate dehydrogenase; PDC, pyruvate dehydrogenase complex; SNP, single nucleotide polymorphismPyruvate dehydrogenase complex deficiency; PDHA1; Mosaicism; Lactic acidosis
Viral triggers for autoimmunity: Is the ‘glass of molecular mimicry’ half full or half empty?
Keywords: PDC، پیرووات دهیدروژناز مجتمع; Cytochrome P450; Virus infection; Tolerance; Liver disease; InflammationGBS, Guillain Barré syndrome; PDC, pyruvate dehydrogenase complex; PBC, primary biliary cirrhosis; 1-OA, 2-octoynoic acid; AIH, autoimmune hepatitis; T1D, type 1 diabetes; LCMV, lymph
Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex
Keywords: PDC، پیرووات دهیدروژناز مجتمع; PDC, pyruvate dehydrogenase complex; E1, pyruvate dehydrogenase; E2, dihydrolipoamide acetyltransferase; E3, dihydrolipoamide dehydrogenase; BP, E3-binding protein; L2S, fragment containing the second lipoyl domain (L2), the second hinge region, the E1-bi
Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart
Keywords: PDC، پیرووات دهیدروژناز مجتمع; GLUT 1, glucose transporter 1; GLUT 4, glucose transporter 4; HK II, hexokinase II; INSR, insulin receptor; CPT IA, carnitine palmitoyltransferase IA; CPT IB, carnitine palmitoyltransferase IB; PDC, pyruvate dehydrogenase complex; PDC-E1, pyruvate dehydro
Amino acid residues responsible for the recognition of dichloroacetate by pyruvate dehydrogenase kinase 2
Keywords: PDC، پیرووات دهیدروژناز مجتمع; PDC, pyruvate dehydrogenase complex; PDHK, pyruvate dehydrogenase kinase; PDHK1, PDHK2, PDHK3, and PDHK4, isozymes 1, 2, 3, and 4 of pyruvate dehydrogenase kinase; E1, pyruvate dehydrogenase component of PDC; E2, dihydrolipoyl acetyltransferase component
Identification of a novel PP2C-type mitochondrial phosphatase
Keywords: PDC، پیرووات دهیدروژناز مجتمع; PTMP, PP2C-type mitochondrial phosphatase; PDC, pyruvate dehydrogenase complex; BCKDC, branched-chain α-keto acid dehydrogenase complex; PDP, PDC phosphatase; PDK, PDC kinase; BDK, BCKDC kinase; BDP, BCKDC phosphataseProtein phosphatase 2C; Mitochondria;
Crystal Structure of an Asymmetric Complex of Pyruvate Dehydrogenase Kinase 3 with Lipoyl Domain 2 and its Biological Implications
Keywords: PDC، پیرووات دهیدروژناز مجتمع; PDC, pyruvate dehydrogenase complex; E1, pyruvate dehydrogenase; E2, dihydrolipoamide transacetylase; E3, dihydrolipoamide dehydrogenase; PDHK, pyruvate dehydrogenase kinase; L2, the inner lipoyl-bearing domain of E2; R-domain, regulatory domain of PDHK;
Crystal Structure of Pyruvate Dehydrogenase Phosphatase 1 and its Functional Implications
Keywords: PDC، پیرووات دهیدروژناز مجتمع; PDC, pyruvate dehydrogenase complex; E1, pyruvate dehydrogenase; E2, dihydrolipoyl acetyltransferase; E3, dihydrolipoyl dehydrogenase; PDP, pyruvate dehydrogenase phosphatase; PDP1r, regulatory subunit of PDP; PDP1c, catalytic subunit of PDP; PP2C, protei