Keywords: PDH، پیرووات دهیدروژناز; DHTKD1, dehydrogenase E1 and transketolase domain containing 1; H2O2, hydrogen peroxide; OA, 2-oxoadipate; OADH, 2-oxoadipate dehydrogenase; OGDH, 2-oxoglutarate dehydrogenase; PDH, pyruvate dehydrogenase; BCOAD, branched chain 2-oxoacid dehydrogenase; KM
مقالات ISI PDH، پیرووات دهیدروژناز (ترجمه نشده)
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Keywords: PDH، پیرووات دهیدروژناز; PDC, pyruvate dehydrogenase complex; PDH, pyruvate dehydrogenase; PDHA1, human gene that encodes α subunit of PDH; Pdha1, murine orthologue of PDHA1; wt, wild-type Pdha1 allele; flox8, Pdha1 floxed allele; Δex8, Pdha1 null allele; E18, embryonic day 18; P
Keywords: PDH، پیرووات دهیدروژناز; GAD, glutamate decarboxylase; GLN, glutamine; GLU, glutamate; GS, glutamine synthetase; KG, α-ketoglutarate; MRS, magnetic resonance spectroscopy; PC, pyruvate carboxylase; PDH, pyruvate dehydrogenase; TCA, tricarboxylic acidGlutamate; Lactate; Astrocytes
Keywords: PDH، پیرووات دهیدروژناز; Pyruvate dehydrogenase deficiency; Paroxysmal exercise-induced dystonia; Brain MRS; Thiamine-responsive dystoniaMRS, magnetic resonance spectroscopy; MRI, magnetic resonance imaging; PDH, pyruvate dehydrogenase; WB, western blot; PED, paroxysmal exercise
Keywords: PDH، پیرووات دهیدروژناز; GDC, glycine decarboxylase; mtPDC, mitochondrial PDC; МDН, malate dehydrogenase; NAD-ME, NAD-malic enzyme; РDС, pyruvate dehydrogenase complex; P-PDH-phosphatase, phospho-PDH-phosphatase; PDH, pyruvate dehydrogenase; РЕР, phosphoenolpyruvate; PVP, polyvin
Keywords: PDH، پیرووات دهیدروژناز; BSA, bovine serum albumin; 2-DG, 2-Deoxyglucose; GSEA, Gene Set Enrichment Analysis; imKO, inducible muscle-specific Bmal1 knockout; HK2, hexokinase 2; KHB, Krebs–Henseleit buffer; mKO, muscle-specific Bmal1 knockout; PDH, pyruvate dehydrogenase; PDK, PDH
A light–dark shift strategy derived from light-responded metabolic behaviors for polyketides production in marine fungus Halorosellinia sp.
Keywords: PDH، پیرووات دهیدروژناز; F-6-P, fructose-6-phosphate; F-1,6-2P, fructose-1,6-bisphosphate; PEP, phosphoenolpyruvate; PFK, phosphofructokinase; PK, pyruvate kinase; PDC, pyruvate dehydrogenase complex; PDH, pyruvate dehydrogenase; CS, citrate synthase; ICDH, isocitrate dehydrogena
Behaviour and prefrontal protein differences in C57BL/6N and 129 X1/SvJ mice
Keywords: PDH، پیرووات دهیدروژناز; PPI, prepulse inhibition; mPFC, medial prefrontal cortex; PLS-DA, partial least squares-discriminant analysis; SOD2, superoxide dismutase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PDH, pyruvate dehydrogenase; GLAST, astrocyte glutamate transporter
In vivo metabolic flux profiling with stable isotopes discriminates sites and quantifies effects of mitochondrial dysfunction in C. elegans
Keywords: PDH، پیرووات دهیدروژناز; C. elegans, Caenorhabditis elegans; RC, respiratory chain; PDH, pyruvate dehydrogenase; TCA, tricarboxylic acid; GC/MS, gas chromatography/mass spectrometry; HPLC, high performance liquid chromatography; RNAi, RNA interference; BCAA, branched chain amino
2-Deoxyglucose treatment complements the cisplatin- or BH3-only mimetic-induced suppression of neuroblastoma cell growth
Keywords: PDH، پیرووات دهیدروژناز; 2DG, 2-deoxyglucose; HIF-1, hypoxia-inducible factor-1; HXK II, hexokinase II; NB, neuroblastoma; PDH, pyruvate dehydrogenase; PDK1, pyruvate dehydrogenase kinase 1; PI, propidium iodideABT737; Apoptosis; 2-Deoxyglucose; Glycolysis; Neuroblastoma
Metabolic changes during ovarian cancer progression as targets for sphingosine treatment
Keywords: PDH، پیرووات دهیدروژناز; So, sphingosine; TCA, tricarboxylic acid cycle; FASN, fatty acid synthase; β-HAD, β-hydroxyl-CoA dehydrogenase; PDH, pyruvate dehydrogenase; OCR, oxygen consumption rate; ECAR, extracellular acidification rateMetabolism; Cancer progression; Sphingosine; S
Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells
Keywords: PDH، پیرووات دهیدروژناز; NNT, nicotinamide nucleotide transhydrogenase; PDH, pyruvate dehydrogenase; SCOT, succinyl-CoA:3-oxoacid CoA transferase; DCF, 2′,7′-dichlorodihydrofluorescein; OCR, oxygen consumption rate; ECAR, extracellular acidification rate; JNK, c-Jun N-terminal ki
Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model
Keywords: PDH، پیرووات دهیدروژناز; GP, glycogen phosphorylase; G6P, glucose-6-phosphate; PC, pyruvate carboxylase; PDH, pyruvate dehydrogenase; SprD, Sprague–Dawley; ZDF, Zucker Diabetic FattyBrain metabolism; 13C-glucose; Glycogen phosphorylase; CP-316,819; SprD; ZDF
Comprehensive analysis of endoplasmic reticulum-enriched fraction in root tips of soybean under flooding stress using proteomics techniques
Keywords: PDH، پیرووات دهیدروژناز; APX, ascorbate peroxidase; CBB, Coomassie brilliant blue; CNX, calnexin; ER, endoplasmic reticulum; HIS, histone H1; LC, liquid chromatography; MS, mass spectrometry; PAGE, polyacrylamide gel electrophoresis; PDH, pyruvate dehydrogenase; qRT-PCR, quantita
Somatic mosaicism for PDHA1 mutation in a male with pyruvate dehydrogenase complex deficiency
Keywords: PDH، پیرووات دهیدروژناز; PDH, pyruvate dehydrogenase; PDC, pyruvate dehydrogenase complex; SNP, single nucleotide polymorphismPyruvate dehydrogenase complex deficiency; PDHA1; Mosaicism; Lactic acidosis
Thermal sensitivity of cardiac mitochondrial metabolism in an ectothermic species from a cold environment, Atlantic wolffish (Anarhichas lupus)
Keywords: PDH، پیرووات دهیدروژناز; OXPHOS, Oxidative phosphorylation; ETS, Electron transport system; CS, Citrate synthase; TCA, Tricarboxylic acid (TCA); PDH, Pyruvate dehydrogenase; BSA, Bovine serum albumin; RCR, Respiratory control ratio; INT, p-iodonitrotetrazolium violetElectron tran
Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence
Keywords: PDH، پیرووات دهیدروژناز; AD, Alzheimer's disease; 3xTgAD, triple transgenic Alzheimer's disease; nonTg, non-transgenic; E2, 17β-estradiol; PDH, pyruvate dehydrogenase; COX, cytochrome c oxidaseMitochondria; Bioenergetics; Reproductive senescence; Alzheimer's disease; Estrogen
An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays
Keywords: PDH، پیرووات دهیدروژناز; PDH, pyruvate dehydrogenase; ICDH, isocitrate dehydrogenase; αKGDH, αketoglutarate dehydrogenase; TCA, tricarboxylic acid cycle; ETC, electron transport chain; NADH, reduced nicotine adenine dinucleotide; FADH2, reduced flavin adenine dinucleotide; BSA, b
FATP1 localizes to mitochondria and enhances pyruvate dehydrogenase activity in skeletal myotubes
Keywords: PDH، پیرووات دهیدروژناز; FATP1, fatty acid transport protein 1; PDH, pyruvate dehydrogenase; PDK, pyruvate dehydrogenase kinase; FA, fatty acid; FAT, fatty acid translocase FAT/CD36; TAG, triacylglyceride; GFP, green fluorescent protein; FCCP, carbonyl cyanide p-trifluoromethoxyp
Effects of homocysteine on metabolic pathways in cultured astrocytes
Keywords: PDH، پیرووات دهیدروژناز; PDK-2, pyruvate dehydrogenase kinase isoform 2; PDH, pyruvate dehydrogenase; PC, pyruvate carboxylase; ALAT, alanine aminotransferase; AST, aspartate aminotransferase; GSH, glutathioneHomocysteine; Astrocytes; Metabolism
MuRF1-dependent Regulation of Systemic Carbohydrate Metabolism as Revealed from Transgenic Mouse Studies
Keywords: PDH، پیرووات دهیدروژناز; GTT, glucose tolerance test; MuRF1, muscle-specific RING finger protein; PDH, pyruvate dehydrogenase; PDK4, pyruvate dehydrogenase kinase, isozyme 4; PKM2, pyruvate kinase, muscle; TG, transgene; WT, wild type, Y2H, yeast two-hybrid; HIBADH, 3-hydroxyisob
Distinct Modes of Recognition of the Lipoyl Domain as Substrate by the E1 and E3 Components of the Pyruvate Dehydrogenase Multienzyme Complex
Keywords: PDH، پیرووات دهیدروژناز; 2-OADH, 2-oxo acid dehydrogenase; LD, lipoyl domain; PSBD, peripheral subunit-binding domain; PDH, pyruvate dehydrogenase; HSQC, heteronuclear single-quantum coherence; ThDP, thiamine diphosphatepyruvate dehydrogenase; multienzyme complex; lipoyl domain;
Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism
Keywords: PDH، پیرووات دهیدروژناز; 3HG, 3-hydroxyglutaric acid; CAT, catalase; CK, creatine kinase; GA, glutaric acid; GA I, glutaric acidemia type I; GSH, reduced glutathione; l-NAME, Nω-nitro-l-arginine methyl ester; PDH, pyruvate dehydrogenase; QA, quinolinic acid; SOD, superoxide dismu
Characterization of a lipoate-protein ligase A gene of rice (Oryza sativa L.)
Keywords: PDH، پیرووات دهیدروژناز; ACP, acyl carrier protein; BCODH, branched-chain α-ketoacid dehydrogenase complex; KGDH, α-ketoglutarate dehydrogenase; OGDH, 2-oxoglutarate dehydrogenase; ORF, open reading frame; PCR, polymerase chain reaction; PDH, pyruvate dehydrogenase; PIG-F, Phosph
The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes
Keywords: PDH، پیرووات دهیدروژناز; AAT, aspartate aminotransferase; ALAT, alanine aminotransferase; HE, hepatic encephalopathy; GDH, glutamate dehydrogenase; α-KGDH, α-ketoglutarate dehydrogenase; PBS, phosphate-buffered saline; PC, pyruvate carboxylase; PDH, pyruvate dehydrogenase; TCA, t
Knockdown of Human Oxa1l Impairs the Biogenesis of F1Fo-ATP Synthase and NADH:Ubiquinone Oxidoreductase
Keywords: PDH، پیرووات دهیدروژناز; OXPHOS, oxidative phosphorylation system; CcO, cytochrome c oxidase; SDH, succinate:ubiquinone oxidoreductase; CS, citrate synthase; SDHA, 70 kDa flavoprotein subunit of SDH; PDH, pyruvate dehydrogenase; HEK293, human embryonic kidney 293; RNAi, RNA inter
Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Cα in C2C12 myocytes
Keywords: PDH، پیرووات دهیدروژناز; CcO, cytochrome c oxidase; PDH, pyruvate dehydrogenase; PKC, protein kinase C; PMA, phorbol 12-myristate 13-acetate; ROS, reactive oxygen species
Changes in gene expression involved in energy utilization during chicken follicle development
Keywords: PDH، پیرووات دهیدروژناز; SWF, small white follicle; SYF, small yellow follicle; F5-1, follicle 5-1; GLUT isoforms, glucose transporter 1-8; HK I and II, hexokinase I and II; PDH, pyruvate dehydrogenase; CS, citrate synthase; CPT I and II, camitine palmityl CoA transferase I and I