
P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model
Keywords: پپت 1; ab; apical to basolateral; AQ; absorptive quotient; AUCT; area under the curve; ba; basolateral to apical; ClR; renal clearance; Cmax; maximum plasma concentration; CYP; cytochrome P450; ER; efflux ratio; F; fraction not metabolised; FA; fraction absorbed