pH-responsive and enzymatically-responsive hydrogel microparticles for the oral delivery of therapeutic proteins: Effects of protein size, crosslinking density, and hydrogel degradation on protein delivery
Keywords: Oral drug delivery; pH-responsive hydrogels; Protein therapeutics; Itaconic acid; Isoelectric point; Enzyme-responsive; Crosslinking density; Salmon calcitonin; Rituxan; Urokinase