Keywords: AMPK; AMP-activated protein kinase; ARF6; ADP-ribosylation factor 6; AKT; protein kinase B; BBB; blood brain barrier; bFGF; b-fibroblast growth factors; b-FGFR; b-fibroblast growth factors receptor; ccRCC; clear cell renal cell carcinoma; ECs; endothelial
مقالات ISI (ترجمه نشده)
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Keywords: AF; S-triethyl phosphine gold(I)-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside (Auranofin); AP-1; activator protein 1; ARE; antioxidant response element; ASK1; apoptosis signal-regulating kinase 1; [Au(dppe)2]Cl; [bis(diphenylphosphino)ethane]gold(I)
Keywords: ALK1; activin receptor-like kinase1; ANG/Ang; angiopoietin; Bcl-xL; b-cell lymphoma-extra large; BM; bone marrow; BMDCs; bone marrow derived cells; BMP; bone morphogenetic protein; Bv8; bombina variagata peptide 8; CAFs; cancer/carcinoma associated fibrob
Keywords: CSC; cancer stem cells; CSF-1; colony stimulating factor-1; EGF; epidermal growth factor; HIF; hypoxia inducible factor; IDO; indoleamine-pyrrole 2,3-dioxygenase; NO; nitric oxide; NLGP; neem leaf glycoprotein; PHD2; prolylhydroxylase domain 2; STAT; sign
Keywords: siRNA; Acellular dermal matrix; Alloderm; Wound healing; Graft incorporation; Graft vascularity; PHD2
Hypoxia enhances H2O2-mediated upregulation of hepcidin: Evidence for NOX4-mediated iron regulation
Keywords: β2mg; β2-microglobulin; BMP; Bone morphogenetic protein; CAT; Catalase; FPN1; ferroportin 1; GOX; Glucose Oxidase; HIF; Hypoxia inducible factor; IL-6; Interleukin 6; JAK; Janus kinase; NOX; NADPH oxidase; ODD; Oxygen-dependent degradation domain; PHD2;
GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma
Keywords: AA; arachidonic acid; AB; alveolar bud; AAA; aromatic amino acid; BCAA; branched chain amino acid; BSA; bovine serum albumin; BMRB; biological magnetic resonance databank; CEC; cuboidal epithelial cell; CPMG; carr-purcell-meiboom-gill; DMBA; 7, 12-d
TP0463518, a novel inhibitor for hypoxia-inducible factor prolyl hydroxylases, increases erythropoietin in rodents and monkeys with a good pharmacokinetics-pharmacodynamics correlation
Keywords: Erythropoietin; PHD2; TP0463518; Pharmacokinetics-pharmacodynamics correlation;
Distinct hypoxic regulation of preadipocyte factor-1 (Pref-1) in preadipocytes and mature adipocytes
Keywords: ARNT; aryl hydrocarbon receptor nuclear translocator; C/EBP; CCAAT-enhancer-binding proteins; CM; conditioned media; Epi; epididymal adipose tissue; HFD; high fat diet; HIF-1; hypoxia-inducible factor-1; HRE; hypoxia responsive elements; MDI; 3-isobutyl-1
NMR studies of the non-haem Fe(II) and 2-oxoglutarate-dependent oxygenases
Keywords: 2OG; 2-Oxoglutarate; BBOX; γ-Butyrobetaine hydroxylase; CODD; C-terminal oxygen-dependent degradation domain; COSY; Correlation spectroscopy; DSBH; Double-stranded β-helix; EFE; Ethylene-forming enzyme; FIH; Factor-inhibiting hypoxia-inducible factor; H
Prolyl hydroxylase-2 inhibits liver tumor cell proliferation and cyclin D1 expression in a hydroxylase-dependent manner
Keywords: PHD2; Cyclin D1; Tumor suppressor; Liver cancer; Doxycycline;
Molecular characterization and mRNA expression of HIF-prolyl hydroxylase-2 (phd2) in hypoxia-sensing pathways from Megalobrama amblycephala
Keywords: Megalobrama amblycephala; Phd2; Hif-1α; Hypoxia; Expression
Gambogic acid inhibits angiogenesis through inhibiting PHD2-VHL-HIF-1α pathway
Keywords: GA; Angiogenesis; VEGF; HIF-1α; VHL; PHD2;
Inhibition of a prolyl hydroxylase domain (PHD) by substrate analog peptides
Keywords: HIF-1α; PHD2; Substrate analog peptides; Peptide inhibitors; Hypoxia
Reduced expression of PHD2 prolyl hydroxylase gene in primary advanced uterine cervical carcinoma
Keywords: Cervical cancer; PHD2; Hypoxia
Inactivation of prolyl hydroxylase domain (PHD) protein by epigallocatechin (EGCG) stabilizes hypoxia-inducible factor (HIF-1α) and induces hepcidin (Hamp) in rat kidney
Keywords: EGCG; Hypoxia; PHD2; HIF-1a; Iron homeostasis; Hepcidin;
Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase
Keywords: ARD; adult Refsum disease; DSBH; double-stranded beta-helix; EctD; ectoine hydroxylase; FIH; factor inhibiting hypoxia-inducible factor; 2OG; 2-oxoglutarate; PAHX; phytanoyl-CoA hydroxylase; PHD2; prolyl hydroxylase isoform 2; SyrB2; 2OG dependent halogen
Interactive effects of cadmium and hypoxia on metabolic responses and bacterial loads of eastern oysters Crassostrea virginica Gmelin
Keywords: AEC; adenylate energy charge; ADP; adenosine-5â²-diphosphate; AMP; adenosine-5â²-monophosphate; ATP; adenosine-5â²-triphosphate; ASW; artificial seawater; Cd; cadmium; cDNA; complementary DNA; COX; complex IV (cytochrome c oxidase); CS; citrate synthas
The multiple roles of amphiregulin in human cancer
Keywords: AREG; amphiregulin; TACE; tumor-necrosis factor-alpha converting enzyme; ADAM; a disintegrin and metalloproteinase; CTF; carboxy-terminal fragment; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EGFR-TKI; epidermal growth factor rec
Relationship among circulating hemoglobin, nitric oxide synthase activities and angiogenic poise in red- and white-blooded Antarctic notothenioid fishes
Keywords: Hb; hemoglobin; Hct; hematocrit; NO; nitric oxide; NOS; nitric oxide synthase; eNOS; endothelial nitric oxide synthase; iNOS; inducible nitric oxide synthase; nNOS; neuronal nitric oxide synthase; NOx; nitrite plus nitrate; VEGF; vascular endothelial grow
Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma
Keywords: GBM; glioblastoma multiforme; BMP2; bone morphogenetic protein2; HIF-1α; hypoxia inducible factor 1α; PHD2; prolyl hydroxylase2; SDH; succinate dehydrogenase; 2-Deoxyglucose; Hypoxia; Hypoxia inducible factor-1α; Prolyl hydroxylase 2; GBM differentiati
Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors
Keywords: Nitric oxide; PHD activity; PHD2; HIF-1; pVHL; Feedback loop
Rotation-vibration energy cluster formation in XH2D and XHD2 molecules (XÂ =Â Bi, P, and Sb)
Keywords: BiH2D; BiHD2; PH2D; PHD2; SbH2D; SbHD2; Energy clusters; Rotational energy surface; Local modes; Variational calculations; Semiclassical analysis;
Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology
Keywords: 2-Oxoglutarate; HIF; Non-heme iron; Oxygen; PHD2; Prolyl hydroxylase; Von Hippel–Lindau protein; vHL
Disturbance in the HIF-1α pathway associated with erythrocytosis: Further evidences brought by frameshift and nonsense mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene
Keywords: Erythrocytosis; Polycythemia; PHD2; HIF-1α; Oxygen sensor
The zinc chelator, N,N,N′,N′-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1α protein in normoxic cells
Keywords: Hypoxia; HIF-1α; TPEN; Ubiquitination; PHD2; FIH-1