Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase
Keywords: فنیل متیل سولفونیل فلوراید; Design; Inflammation; 5-Lipoxygenase; Pharmacophore/docking; Thiazoles; AA; Arachidonic acid; DMF; N,N-dimethylformamide; DMSO; Dimethyl sulphoxide; DPPH; 2,2 -diphenyl-1-picrylhydrazyl; EDTA; Ethylenediaminetetra acetic acid; 5-HPETE; 5(S) hydroperoxyeic