Implication of JNK pathway on tau pathology and cognitive decline in a senescence-accelerated mouse model
Keywords: PHF، رشته های هلی کوپینگ جفت شده; AD, Alzheimer's disease; Cdk5, cyclin-dependent kinase; GSK-3β, glycogen synthase kinase 3 beta; JNK, c-Jun N-terminal kinase; MAPKs, mitogen-activated protein kinases; NFT, neurofibrillary tangles; PHF, paired helical filaments; PP2A, protein phosphatase