Function of the chondrocyte PI-3 kinase-Akt signaling pathway is stimulus dependent
Keywords: PI-3 کیناز; PI-3 kinase; Chondrocyte; Cell signaling; Matrix metalloproteinase-13;
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Dual inhibition of allosteric mitogen-activated protein kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) oncogenic targets with a bifunctional inhibitor
Keywords: PI-3 کیناز; Dual inhibition; Akt; ERK; PI-3 Kinase; MEK1; MAP Kinase; Oncogenic signaling; KRAS; Driven oncogenesis;
Palmitic acid suppresses apolipoprotein M gene expression via the pathway of PPARβ/δ in HepG2 cells
Keywords: PI-3 کیناز; Apolipoprotein M; Palmitic acid; Peroxisome proliferator-activated receptor beta/delta; PI-3 kinase; Protein kinase C;
A quinazoline-derivative compound with PARP inhibitory effect suppresses hypertension-induced vascular alterations in spontaneously hypertensive rats
Keywords: PI-3 کیناز; AngII; angiotensin II; AIF; apoptosis inducing factor; ASI; Aortic stiffness index; AP-1; activator protein 1; ASK1; apoptosis signal-regulating kinase 1; Crm1; chromosome region maintenance 1; DAB; 3,3â²-diaminobenzidine; DBP; diastolic blood pressure;
The biological rationale and clinical efficacy of inhibition of signaling kinases in chronic lymphocytic leukemia
Keywords: PI-3 کیناز; Chronic lymphocytic leukemia; Microenvironment; Signaling; BTK; Syk; PI-3 kinase
C-peptide induces human renal mesangial cell proliferation in vitro, activating Src-kinase, PI-3 kinase and ERK1/2
Keywords: PI-3 کیناز; CDK4; cyclin-dependent kinase 4; DAPI; 4â²,6-diamidino-2-phenylindole; ERK1/2; extracellular-signal-regulated kinases; LY294002; PI-3 kinase inhibitor; MC; mesangial cells; PD98059; MAP/ERK kinase inhibitor; PDGF; platelet derived growth factor; PP2; pro
Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling
Keywords: PI-3 کیناز; Actin cytoskeleton; WAVE complex; Abi1; PI-3 kinase; SH2 domain;
Disruption of Platelet-Derived Growth Factor–Dependent Phosphatidylinositol 3-Kinase and Phospholipase Cγ 1 Activity Abolishes Vascular Smooth Muscle Cell Proliferation and Migration and Attenuates Neointima Formation In Vivo
Keywords: PI-3 کیناز; PI-3 kinase; PLCγ; platelet-derived growth factor; proliferation; restenosisBrdU, 5-bromodeoxyuridine; cdk, cyclin-dependent kinase; ChiR, chimeric receptor; CSF1R, colony-stimulating factor-1 receptor; ECM, extracellular matrix; M-CSF, macrophage colony-
PRK1 distribution in normal tissues and carcinomas: overexpression and activation in ovarian serous carcinoma
Keywords: PI-3 کیناز; PRK1; Androgen receptor; PI-3 kinase; Prostate cancer; Ovarian cancer; Immunohistochemistry
Tetraspanin CD9 regulates β1 integrin activation and enhances cell motility to fibronectin via a PI-3 kinase-dependent pathway
Keywords: PI-3 کیناز; Tetraspanins; CD9; Fibronectin; Extracellular matrix; Cell migration; Integrin; α5β1; Signal transduction; PI-3 kinase; Akt
Suppression of phosphoenolpyruvate carboxykinase gene expression by reduced endogenous glutathione level
Keywords: PI-3 کیناز; Glutathione; PEPCK; Hepatocytes; Ageing and diabetes; PI-3 kinase
Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation
Keywords: PI-3 کیناز; Apolipoprotein B; mRNA; Translation; Untranslated region; Insulin signaling; PI-3 kinase; IRES;
Autocrine anti-apoptotic and proliferative effects of insulin in pancreatic β-cells
Keywords: PI-3 کیناز; Pancreatic β-cell; Apoptosis; Proliferation; Insulin; Autocrine; PI-3 kinase;
Leptin inhibits 1-methyl-4-phenylpyridinium-induced cell death in SH-SY5Y cells
Keywords: PI-3 کیناز; Leptin; MPP+; Cytoprotective effects; PI-3 kinase; Obesity;
Phosphorylation at the hydrophobic site of protein kinase C Apl II is increased during intermediate term facilitation
Keywords: PI-3 کیناز; Aplysia; learning and memory; phosphoinositide dependent kinase I; persistent protein kinase; rapamycin; autophosphorylation; PDBu; phorbol dibutyrate; PDK-1; phosphoinositide-dependent kinase I; PI-3 kinase; phosphoinositide-3 kinase; PKC; protein kinase
FGF signal transduction and the regulation of Cdx gene expression
Keywords: PI-3 کیناز; Xenopus; FGF; Cdx; ERK; PI-3 kinase; Mesoderm;
mTOR: A placental growth signaling sensor
Keywords: PI-3 کیناز; Trophoblast proliferation; Growth factors; Glucose; Glucosamine; mTOR; PI-3 kinase; GFAT;
Multiple Anti-apoptotic Pathways Stimulated by EGF in Cytotrophoblasts
Keywords: PI-3 کیناز; Trophoblasts; Signal transduction; ERK; p38; PI-3 kinase; JNK; SPHK-1; S1P; EGF;
EGFR enhances Survivin expression through the phosphoinositide 3 (PI-3) kinase signaling pathway
Keywords: PI-3 کیناز; Cancer; Survivin; EGFR; ErbB; PI-3 kinase; Signal transduction; Radiation; Apoptosis;
Hierarchy of ADAM12 binding to integrins in tumor cells
Keywords: PI-3 کیناز; ADAM12; Adhesion; α9β1 integrin; PI-3 kinase;
Facilitation of conditioned fear extinction by d-cycloserine is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase cascades and requires de novo protein synthesis in basolateral nucleus of amygdala
Keywords: PI-3 کیناز; extinction; D-cycloserine; MAPK; PI-3 kinase; amygdala; ACT+DCS; actinomycin D+d-cycloserine; ACT+SAL; actinomycin D+saline; ANI+DCS; anisomycin+d-cycloserine; ANI+SAL; anisomycin+saline; BLA; basolateral nucleus of the amygdala; CS; conditioned stimulus;