WAVE2 targeting to phosphatidylinositol 3,4,5-triphosphate mediated by insulin receptor substrate p53 through a complex with WAVE2
Keywords: PI 3-kinase، phosphatidylinositol 3-kinase; PIP3, phosphatidylinositol 3,4,5-triphosphate; IGF-I, insulin-like growth factor I; IGF-IR, insulin-like growth factor I receptor; PI 3-kinase, phosphatidylinositol 3-kinase; IRSp53, insulin receptor substrate p53; siRNA, small interfering RNA; RacGEFs, R