PI(3,4,5)P3 and PI(3,4)P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser473, respectively; PI(3,4)P2 levels determine PKB activity
Keywords: PKB, protein kinase B; PI, phosphatidylinositol; PIP, phosphatidylinositol phosphate; PI(3,4,5)P3, phosphatidylinositol 3,4,5-triphosphate; PI(3,4)P2, phosphatidylinositol 3,4,-biphosphate; SHIP, SH2 domain containing inositol phosphatase.PI 3-kinase; Pro