Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
مقالات ISI (ترجمه نشده)
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Keywords: Pax6; Pitx3; Beta-crystallins; Eye disease; Neurogenesis; Parkinson's disease; Neourogenesis; Schizophrenia;
Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; amyloid-β; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; APOE4; apolipoprotein E4; APP; amyloid precursor protein; ASCL1; achaete-scute family basic helix-loop-helix transcription factor 1; ATP; adenosine trip
Keywords: Deleted in colorectal cancer; Dopamine neurons; Orthodenticle homeobox 2; Pitx3; Substantia nigra;
Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice
Keywords: mDANs; midbrain dopaminergic (DA) neurons; OTX2; Orthodenticle homeobox 2; PD; Parkinson's disease; Lmx1b; LIM homeobox transcription factors 1-beta; Pitx3; pituitary homeobox 3; Girk2; G protein-gated inwardly rectifying K+ channel; DAT; dopamine trans
PITX3 genotype and risk of dementia in Parkinson's disease: A population-based study
Keywords: Parkinson's disease; PITX3; Dementia; Parkinson's disease genetics; DAT scan;
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1
Keywords: Dopamine transporter; Epigenetics; HDAC; Valproate; Histone deacetylase; Pitx3; Nurr1;
Photoactivation of ERK/CREB/VMAT2 pathway attenuates MPP+-induced neuronal injury in a cellular model of Parkinson's disease
Keywords: PD; Parkinson's disease; SNpc; substantia nigra pars compacta; DA; dopamine; MPTP; 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium; VMAT2; vesicular monoamine transporter 2; LPLI; low-power laser irradiation; Aβ; amyloi
Efficient generation of dopaminergic-like neurons by overexpression of Nurr1 and Pitx3 in mouse induced Pluripotent Stem Cells
Keywords: Dopaminergic neurons; Induced-pluripotent stem cells; Nurr1; Parkinson’s disease; Pitx3
Association between PITX3 promoter polymorphism and risk of Parkinson's disease: The impact of ethnicity and onset age
Keywords: PITX3; rs3758549; Parkinson's disease; Ethnicity; Onset age; Meta analysis
Impaired motor coordination in Pitx3 overexpression mice
Keywords: Parkinson's disease; Pitx3; Midbrain DA neurons;
Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease
Keywords: SNCA140; PARK; RIN; Mixed-effects-model; miR-133b; NURR1; PITX3; UV-LMD; UCHL-1; ATPase13A2; Parkin; LRRK2;
The BCL2 code to dopaminergic development and Parkinson's disease
Keywords: cell death; dopamine; Parkinson's disease; substantia nigra; NURR1; PITX3; BCL2
Neurochemical profiling of dopaminergic neurons in the forebrain of a cichlid fish, Astatotilapia burtoni
Keywords: aTn; anterior tuberal nucleus; CP; central posterior thalamic nucleus; D; dorsal (pallial) part of the telencephalon; Dc; central part of D; Dc-2; subdivision of Dc; Dd; dorsal part of D; Dl; lateral part of D; Dld; dorsal region of Dl; Dlg; granular regi
Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease
Keywords: Parkinson's disease; Transcription factors; PITX3; EN1;
Hes1 regulates the number and anterior-posterior patterning of mesencephalic dopaminergic neurons at the mid/hindbrain boundary (isthmus)
Keywords: Hes1 knockout mice; Neural tube closure defect; Mesencephalic dopaminergic neurons; Tyrosine hydroxylase; Pitx3; Serotonergic neurons; Isthmic organizer;
Preservation of function in Parkinson's disease: What's learning got to do with it?
Keywords: Corticostriatal plasticity; Models of basal ganglia; Motor learning; Dopamine; Dopamine denervation; PITx3
PITX3 polymorphism is associated with early onset Parkinson's disease
Keywords: Pitx3; Ptx3; Dopamine; Substantia nigra; Dopaminergic neurons; PD; Neuronal development
Pitx3-deficient aphakia mice display unique behavioral responses to psychostimulant and antipsychotic drugs
Keywords: Pitx3; amphetamine; dopamine; dorsal; ventral; striatumDA, dopamine
Transplantable midbrain dopamine neurons: A moving target
Keywords: mDA; midbrain dopaminergic; VZ; ventricular zone; IZ; intermediate zone; MZ; mantle zone; VTA; ventral tegmental area; SN; substantia nigra; Nurr1; nurr77-related receptor 1; PD; Parkinson's disease; TH; tyrosine hydroxylase; VM; ventral mesencephalon; So
Molecular characteristics of inherited congenital cataracts
Keywords: Congenital inherited cataracts; Crystallins; Major intrinsic protein (MIP); Connexins; Lens intrinsic membrane protein (LIM); Vimentin; Beaded filament structural protein 2 (BFSP2); PITX3; PAX6
Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons
Keywords: in vitro differentiation; ventralization factors; TH; Pitx3; HDAC inhibitor; DA; dopamine; FGF8; fibroblast growth factors; nmNSCs; non mesencephalic neural stem cells; Shh; Sonic Hedgehog; TH; tyrosine hydroxylase; TSA; trichostatin A;
Organization of the human embryonic ventral mesencephalon
Keywords: Midbrain; Floor plate; Basal plate; LMX1A; FOXA2; NGN2; PITX3; TH; Parkinson’s disease; Red nucleus; ISL1; BRN3A; NURR1; Dopamine neuron
The transcription factor PITX3 is associated with sporadic Parkinson's disease
Keywords: Parkinson's disease; PITX3; Homeoproteins; SNPs; Midbrain dopaminergic neurons; Association study; Neuronal development
Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells
Keywords: Pitx3; Homeodomain transcription factor; Lens epithelium; Fibre cell; Differentiation
Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis
Keywords: Cell transplantation; Parkinson's disease; Neurogenin-2; Pitx3; Corin; Lmx1a; Cell sorting
Impaired learning and memory in Pitx3 deficient aphakia mice: A genetic model for striatum-dependent cognitive symptoms in Parkinson's disease
Keywords: Cognition; Parkinson's disease; Pitx3; Dopamine; Striatum
Emerging restorative treatments for Parkinson's disease
Keywords: Ad; adenovirus; AAV; adeno-associated virus; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; CD45; cluster of differentiation 45; CNTF; ciliary neurotrophic factor; CSF; cerebrospinal fluid; DAT;
Midbrain dopamine neuron differentiation: Factors and fates
Keywords: Dopamine neuron; Parkinson disease; Stem cell; Midbrain; Floor plate; Sonic hedgehog; nurr1; pitx3
Chronic cocaine administration modulates the expression of transcription factors involved in midbrain dopaminergic neuron function
Keywords: Engrailed; Gene expression; Nurr1; Pitx3; Tyrosine hydroxylase
Molecular genetics of pituitary development in zebrafish
Keywords: Zebrafish; Pituitary; Adenohypophysis; Neurohypophysis; Lineage specification; Pitx3; Shh; Fgf3; Ascl1a; Pit1; Eya1
Zebrafish foxe3: Roles in ocular lens morphogenesis through interaction with pitx3
Keywords: Eye lens; Fox transcription factor; Anterior epithelial cell; Secondary fiber cell; Lens development; Pitx3
Development of the dopaminergic neurons in the rodent brainstem
Keywords: Dopamine; Engrailed; FGF8; GDNF; Lmx1b; Midbrain; Nurr1; Pitx3;
Genetic Mouse Models of Parkinsonism: Strengths and Limitations
Keywords: α-Synuclein; parkin; DJ-1; Nurr1; Pitx3; mice;
Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development
Keywords: Differentiation; Dopaminergic neuron; Embryonic stem cell; GFP; Homeobox; Knock-in; Pitx3; Transcription factor; Tyrosine hydroxylase;
Zebrafish pitx3 is necessary for normal lens and retinal development
Keywords: Pitx3; Lens; Retina; Zebrafish; Morpholino;