دانلود مقالات ISI درباره Pkd1 + ترجمه فارسی

پلیسیستین و سیگنالینگ کلسیم در مرگ و بقای سلول

Polycystin and calcium signaling in cell death and survival

Keywords: PC1; polycystin-1; PC2; polycystin-2; ADPKD; autosomal dominant polycystic kidney disease; PKD1; PC1 gene; PKD2; PC2 gene; ESRD; end stage renal disease; Ca2+; calcium; cAMP; cyclic adenosine monophosphate; MAPK; mitogen-activated protein kinase; mTOR; me

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

کیست های مجتمع کبدی در بیماری کلیوی غده تیروئید اتوزومال

Complex liver cysts in Autosomal Dominant Polycystic Kidney Disease

Keywords: ADPKD; Autosomal Dominant Polycystic Kidney Disease; SI; signal intensity; PKD1; Polycystic Kidney Disease 1 Gene; PKD2; Polycystic Kidney Disease 2 Gene; MRI; Magnetic Resonance Imaging; SSFSE; Single Shot Fast Spin Echo; LAVA; liver accelerated volume a

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

فنوتیپ ترشحی مرتبط با سقط جنین: افتراق بحرانی در سرطان پوست و پیری

The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging

Keywords: ATM; ataxia telangiectasia mutated; DDR; DNA-damage response; MAPK; mitogen-activated protein kinase; MMP; matrix metalloproteinase; mTOR; mammalian target of rapamycin; PKD1; protein kinase D1; SASP; senescence-associated secretory phenotype; SCC; squamo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

دیدگاه پلیسیستین مرکزی از تشکیل کیست و بیماری: پلیسیستین مجددا بازدید شده است

A polycystin-centric view of cyst formation and disease: the polycystins revisited

Keywords: ADPKD; PKD1; PKD2; polycystin-1; polycystin-2; TRPP2;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

مکانیزم های رمز گشایی که از طریق آن کدون سکوت تغییر می کند، بر عملکرد و بیوگرافی پروتئین تاثیر می گذارد

Decoding mechanisms by which silent codon changes influence protein biogenesis and function

Keywords: A; adenine; ACMG; American College of Medical Genetics; Ala; alanine; Asp; aspartic acid; BCL2L12; B-cell lymphoma-2-like protein 12; BRCA1; breast cancer-1 gene; C; cytosine; CCDS; Consensus Coding Sequence; CD; circular dichroism; CDC; coding sequence;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Overexpression of exogenous kidney-specific Ngal attenuates progressive cyst development and prolongs lifespan in a murine model of polycystic kidney disease

Keywords: cysts; neutrophil gelatinase-associated lipocalin; Pkd1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Association of Rare Nonsynonymous Variants in PKD1 and PKD2 with Familial Intracranial Aneurysms in a Japanese Population

Keywords: Intracranial aneurysm; autosomal dominant polycystic kidney disease; PKD1; PKD2; susceptibility gene; rare variant;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Genkwadaphnin promotes leukocyte migration by increasing CD44 expression via PKD1/NF-κB signaling pathway

Keywords: GD, Genkwadaphnin; NF-κB, nuclear factor of kappa light polypeptide gene enhancer in B-cells; PKD1, protein kinase D1; ECM, extracellular matrix; IκBα, inhibitor of NF-κB alphaGenkwadaphnin; CD44; PKD1; NF-κB; Leukocyte; Migration

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease

Keywords: Polycystic kidney disease; Autosomal Dominant Polycystic Kidney Disease; Pkd1; ADPKD; Mouse model; Systems biology; Metabolism; Fatty acid oxidation; Fatty acid oxidation defect; Lipid metabolism; Diet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

miR-181b-3p promotes epithelial-mesenchymal transition in breast cancer cells through Snail stabilization by directly targeting YWHAG

Keywords: AP; alkaline phosphatase; DIG; digoxigenin; CHX; cycloheximide; EGF; epidermal growth factor; EMT; epithelial-mesenchymal transition; FBS; fetal bovine serum; FGF; fibroblast growth factor; GSK3β; glycogen synthase kinase 3β; IHC; immunohistochemistry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Dual effects of the non-esterified fatty acid receptor 'GPR40' for human health

Keywords: AA; arachidonic acids; ABCD; ABC transporters; BDNF; brain-derived neurotrophic factor; BKCa channels; Ca2+-activated K+ channels; cAMP; cyclic AMP; CO; carbon monoxide; CLA; conjugated linoleic acids; CNS; central nervous system; CoA; coenzyme A; CREB; c

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2015 سفارش ترجمه

An autopsy case of subarachnoid hemorrhage due to ruptured cerebral aneurysm associated with polycystic kidney disease caused by a novel PKD1 mutation

Keywords: ADPKD, autosomal dominant polycystic kidney disease; SAH, subarachnoid hemorrhageAutosomal dominant polycystic kidney disease; PKD1; PKD2; Subarachnoid hemorrhage; Genetic analysis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylases in cardiac fibrosis: Current perspectives for therapy

Keywords: HDACs; Histone deacetylases; ECM; Extracellular matrix; α-SMA; α-smooth muscle actin; HATs; Histone acetyltransferases; TGF-β1; Transforming growth factor β1; PDGF; Platelet-derived growth factor; FGF; Fibroblast growth factor; TIMPs; Tissue inhibitor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel mutations of PKD1 gene in Chinese patients with autosomal dominant polycystic kidney disease by targeted next-generation sequencing

Keywords: ADPKD; Mutation; PKD1; Targeted next-generation sequencing;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Protein kinase-D1 overexpression prevents lipid-induced cardiac insulin resistance

Keywords: AMPK; AMP-activated protein kinase; AW; anterior wall; BNP; B-type natriuretic peptide; caPKD1; cardiospecific constitutively active PKD1 overexpression; DAG; diacylglycerol; EFS; electric field stimulation; [18F]FDG; [18F]fluoro-deoxyglucose; [18F]FTHA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The p38 MAPK-regulated PKD1/CREB/Bcl-2 pathway contributes to selenite-induced colorectal cancer cell apoptosis in vitro and in vivo

Keywords: Selenite; Apoptosis; p38 MAPK; PKD1; CREB;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy

Keywords: ADPKD; autosomal dominant polycystic kidney disease; APD; action potential duration; AV; atrioventricular; bpm; beats per minute; dpf; days post fertilization; CICR; calcium-induced calcium release; ER; endoplasmic reticulum; hpf; hours post fertilization

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The role of PKC isoforms in the inhibition of NF-κB activation by vitamin K2 in human hepatocellular carcinoma cells

Keywords: Vitamin K2; NF-κB; PKC; PKD1; Liver cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Crystal structure and characterization of coiled-coil domain of the transient receptor potential channel PKD2L1

Keywords: CRD; cytoplasmic regulatory domain; PKD2L1; polycystic kidney disease 2-like 1; PKD1; polycystic kidney disease 1; PKD1L3; polycystic kidney disease 1-like 3; ER; endoplasmic reticulum; HEK; human embryonic kidney; ADPKD; autosomal dominant polycystic kid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Autosomal dominant polycystic kidney disease is associated with central and nephrogenic defects in osmoregulation

Keywords: arginine vasopressin; cAMP; hypothalamus; polycystins; PKD1; PKD2; vasopressin receptor V2R;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Phosphatidylinositol 3-kinase and protein kinase D1 specifically cooperate to negatively regulate the insulin-like growth factor signaling pathway

Keywords: EGF; epidermal growth factor; ERK; extracellular signal-regulated kinase; FGF; fibroblast growth factor; IGF; insulin-like growth factor; IGF-IR; type 1 IGF receptor; IR; insulin receptor; IRS; insulin receptor substrate; PI 3-kinase; phosphatidylinositol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Determinants of Renal Disease Variability in ADPKD

Keywords: Autosomal dominant polycystic kidney disease; PKD1; PKD2; Disease severity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation

Keywords: Aldosterone; Kidney; PKD1; MAPK; Cell proliferation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease

Keywords: ADPKD; mutation; hypomorphic allele; childhood; PKD1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Autosomal dominant polycystic kidney disease: the last 3 years

Keywords: ADPKD; PKD1; PKD2; polycystic kidney disease; polycystin-1; polycystin-2

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2009 سفارش ترجمه

Amlodipine inhibits cell proliferation via PKD1-related pathway

Keywords: PKD1; Amlodipine; hCASMC;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Analysis of PKD1 for genomic deletion by multiplex ligation-dependent probe assay: Absence of hot spots

Keywords: PKD1; TSC2; MLPA; Large deletions; Polypurine–polypyrimidine tract; Intron 21; Autosomal dominant polycystic kidney disease; Multiplex ligation-dependent probe amplification

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Polycystin-1 induced apoptosis and cell cycle arrest in G0/G1 phase in cancer cells

Keywords: Apoptosis; Cell cycle; Polycystin-1; Proliferation; Wnt pathway; ADPKD; autosomal dominant polycystic kidney disease; PKD1; polycystic kidney disease gene 1; LRR; leucine-rich repeats; WSC; wall integrity and stress-response component; REJ; receptor for e

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Evaluating the clinical utility of a molecular genetic test for polycystic kidney disease

Keywords: Autosomal dominant polycystic kidney disease; ADPKD; Mutation analysis; PKDx®; PKD1; PKD2; DNA testing;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system

Keywords: polycystic kidney disease; ADPKD; proliferation; PKD1; IGF-1; polycystin-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Annexin A5 Interacts with Polycystin-1 and Interferes with the Polycystin-1 Stimulated Recruitment of E-cadherin into Adherens Junctions

Keywords: ADPKD, autosomal dominant polycystic kidney disease; LRR, leucine-rich repeat; GCT, glutathione-S-transferaseANXA5; annexin A5; PKD1; polycystin-1; E-cadherin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

La génétique des polykystoses rénales : mise au point et conseil génétique

Keywords: Polykystose rénale autosomique; Dominant; PKD1; PKD2; Récessif; PKHD1Autosomal polycystic kidney diseases; Dominant; PKD1; PKD2; Recessive; PKHD1PKD, polycystic kidney disease; PKHD, polycystic kidney and hepatic disease; ADPKD, polykystose rénale autosom

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Ets factors regulate the polycystic kidney disease-1 promoter

Keywords: Transcription; Fli-1; Ets-1; PKD1; Drosophila SL2 cells

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Non-B DNA structure-induced genetic instability

Keywords: AID; activation-induced cytidine deaminase; CCE1; cruciform-cutting endonuclease 1; DSBs; double-strand breaks; FEN-1; Flap endonuclease-1; Mbr; major breakpoint region; MMR; mismatch repair; NER; nucleotide excision repair; PKD1; polycystic kidney diseas

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2006 سفارش ترجمه

Cloning and expression of the amphibian homologue of the human PKD1 gene

Keywords: ADPKD; autosomal dominant Polykystoc kidney disease; BAC; Bacterial Artificial Chromosome; ORF; Open Reading Frame; Pc1; Polycystin 1; Pc2; Polycystin 2; PKD1; Gene involved in ADPKD type 1; PKD2; Gene involved in ADPKD type 2; xPKD1; Xenopous homologue o

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Lack of a laterality phenotype in Pkd1 knock-out embryos correlates with absence of polycystin-1 in nodal cilia

Keywords: left-right asymmetry; Pkd1; Pkd2; polycystin 1; polycystin 2; cilia; mouse; rabbit; embryo;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

PKCε-PKD1 signaling complex at Z-discs plays a pivotal role in the cardiac hypertrophy induced by G-protein coupling receptor agonists

Keywords: PKD1; PKC; Hypertrophy; Cardiomyocyte; Z-disc; G-protein coupling receptor; Gp130; α-Adrenergic receptor; Phorbol ester;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling

Keywords: ARPKD; Fibrocystin; CAML; Ca2+signaling; Cilia; PKD1; PKD2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Differential expression of Cux-1 and p21 in polycystic kidneys from Pkd1 null and cpk mice

Keywords: Cux-1; CDP/Cux; polycystic kidney disease; p21; p27; cpk; Pkd1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular pathogenesis of ADPKD: The polycystin complex gets complex

Keywords: ADPKD; PKD1; PKD2; polycystin-1; polycystin-2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه