The oxindole/imidazole derivative C16 reduces in vivo brain PKR activation
Keywords: PKR, double-stranded RNA-dependent protein kinase; mTOR, mammalian target of rapamycin; p70S6K, 70-kDa S6 kinase; eIF2α, eukaryotic initiation factor 2α; C16, oxindole/imidazole compound; AD, Alzheimer’s disease; Aβ, β-amyloid peptide; APP, amyloid precur