Keywords: plasmepsin; PM; plasmepsin; SPP; signal peptide peptidase; HIV; human immunodeficiency virus; SAR; structure-activity relationships; BACE; beta-site APP cleaving enzyme 1 or beta-secretase; TCAMS; Tres Cantos Antimalarial Set; RBC; red blood cells; CatD; cathepsin
مقالات ISI plasmepsin (ترجمه نشده)
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Keywords: plasmepsin; 2D-DIGE; 2-D Fluorescence Difference Gel Electrophoresis; 2D-nanoLC; 2D-nanoflow high-performance liquid chromatography; 2D-PAGE; Two-dimensional gel electrophoresis; 4-HNE; 4-hydroxy-2-nonenal; ASP; Apical sushi protein; G6PD; Glucose-6-phosphate dehydro
Plerixafor and related macrocyclic amines are potential drug candidates in treatment of malaria by “filling the flap” region of plasmepsin enzymes
Keywords: plasmepsin; Plerixafor; Plasmepsin; Malaria; Macrocycle; Hemoglobin; Heme;
Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2 position of PEXEL peptidomimetics
Keywords: plasmepsin; Plasmepsin; Malaria; Protease; Peptidomimetic; PEXEL; Trafficking; Abu; aminobutyric acid; Cav; canavanine; CyHexGly; cyclohexylglycine; CyPenGly; cyclopentylglycine; EtNva; beta-ethyl-norvaline; GFP; green fluorescent protein; HBTU; O-(benzotriazol-1-yl)
Plasmodium berghei plasmepsin VIII is essential for sporozoite gliding motility
Keywords: plasmepsin; Plasmodium; Malaria; Gliding motility; Plasmepsin; Oocyst; Invasion;
The zymogen of plasmepsin V from Plasmodium falciparum is enzymatically active
Keywords: plasmepsin; DABCYL; 4-((4-(dimethylamino)phenyl)azo)benzoic acid; EDANS; 5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid; KNI; kinostatin; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; CHES; 2-(cyclohexylamino)ethanesulfonic acid; MES; 2-(N-mor
Structural studies of vacuolar plasmepsins
Keywords: plasmepsin; Aspartic protease; Malaria; Crystal structure; Plasmepsin; Inhibitors;
Research BriefToxoplasma gondii aspartic protease 1 is not essential in tachyzoites
Keywords: plasmepsin; Toxoplasma gondii; Aspartic protease; Plasmepsin;
Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum
Keywords: plasmepsin; Malaria; Plasmepsin; Aspartic protease; Crystal structure; Enzyme inhibition
Antiplasmodial activity of Punica granatum L. fruit rind
Keywords: plasmepsin; Punica granatum; Dalima; Plasmodium; Ellagitannins; Malaria; Plasmepsin; Antiparasitic remedy;
α-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases
Keywords: plasmepsin; Malaria; Plasmepsin; Inhibitors; Microwave-assisted synthesis; Molecular dynamics; Linear interaction energy mehtod
Identification of acridinyl hydrazides as potent aspartic protease inhibitors
Keywords: plasmepsin; Virtual screening; Protease inhibitors; Cathepsin D; Plasmepsin; Acridines
Effects on growth, hemoglobin metabolism and paralogous gene expression resulting from disruption of genes encoding the digestive vacuole plasmepsins of Plasmodium falciparum
Keywords: plasmepsin; Plasmepsin; Aspartic proteinase; Gene knockout; Transfection; Malaria; Plasmodium; Hemoglobin
Computational analysis of plasmepsin IV bound to an allophenylnorstatine inhibitor
Keywords: plasmepsin; Apn, allophenylnorstatine; LIE, linear interaction energy; MD, molecular dynamics; PmPM IV, Plasmodium malariae plasmepsin IV; PfPM IV, Plasmodium falciparum plasmepsin IV; RMSD, root mean square deviationMalaria; Plasmepsin; Enzyme inhibitors; Linear int
Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum
Keywords: plasmepsin; PM, plasmepsin; HAP, histo-aspartic protease; SNP, single nucleotide polymorphism; kb, kilobase; bp, base pairs; CDS, coding sequence.Drug target; Plasmepsin; Population genetics; SNP; Microsatellites; var genes
Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV
Keywords: plasmepsin; Malaria; Plasmepsin; Protease inhibitors and molecular dynamics
Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II
Keywords: plasmepsin; Malaria; Plasmepsin; Hydroxyethylamine; Molecular modeling;