
TRAF6 promotes ubiquitination and regulated intramembrane proteolysis of IL-1R1
Keywords: PMA, phorbol 12-myristate-13-acetate; TNF, tumor necrosis factor; TRAF6, tumor necrosis factor receptor-associated factor-6; CTD, C-terminal fragment; ICD, intracellular domain; IL, interleukin; PS, presenilin; RIP, regulated intramembrane proteolysisInte