Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene
Keywords: ARE, antioxidant response element; CAT, catalase; GPx, glutathione peroxidase; HO-1, heme oxygenase-1; NF-κB p65, nuclear factor kappa B; Nrf2, NF-E2-related factor 2; NP-40, nonidet P-40; PMSF, phenylmethylsulfonyl-fluoride; ROS, reactive oxygen species;