Kinetic isotope effects in the characterization of catalysis by protein tyrosine phosphatases
Keywords: pNPP، para-nitrofenyl phosphate; PTP, protein tyrosine phosphatase; DSP, dual specificity phosphatase; KIE, kinetic isotope effect; LFER, linear free energy relationship; IRMS, isotope ratio mass spectrometer; pNPP, para-nitrophenyl phosphate; mNBP, meta-nitrobenzyl phosphateProtein-tyro