دانلود مقالات ISI درباره Pnu-120596 + ترجمه فارسی

Counteracting desensitization of human α7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning

Keywords: AChE; acetylcholinesterase; ACh; acetylcholine; BP; bispyridinium; CNS; central nervous system; 7α-nAChRs; human α7-nicotinic acetylcholine receptor(s); mAChR; muscarinic acetylcholine receptor; nAChRs; nicotinic acetylcholine receptor(s); OP; organopho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis

Keywords: AChE; acetylcholinesterase; ACh; acetylcholine; BP; bispyridinium; CNS; central nervous system; I‐; iodide; mAChR(s); muscarinic acetylcholine receptor(s); MLA; methyllycaconitine citrate; nAChR(s); nicotinic acetylcholine receptor(s); OP; organophospho

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Nicotinic acetylcholine receptor-mediated GABAergic inputs to cholinergic interneurons in the striosomes and the matrix compartments of the mouse striatum

Keywords: Acetylcholine; Nicotinic; Cholinergic interneuron; Striosome; Matrix; ABT-418; 3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; ACh; acetylcholine; AChE; acetylcholinesterase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective

Keywords: Cys-loop receptors; Nicotinic receptors; Patch-clamp; Single-channel recordings; Positive allosteric modulators; nAChR; nicotinic acetylcholine receptor; ACh; acetylcholine; 5-HT3A; serotonin type 3A receptor; PAM; positive allosteric modulator; PAM-2; 3-

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Research ReportMaximizing the effect of an α7 nicotinic receptor PAM in a mouse model of schizophrenia-like sensory inhibition deficits

Keywords: Schizophrenia; Sensory inhibition; Auditory gating; DBA/2 mice; C3H heterozygote Chrna7 null mutant mice; Positive allosteric modulator; PAM; α7 Nicotinic receptor; PNU-120596;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Mode of action of the positive modulator PNU-120596 on α7 nicotinic acetylcholine receptors

Keywords: α7 nicotinic acetylcholine receptor; Choline; PNU-120596; Positive allosteric modulator; Mode of actionα7 nAChR, α7 subtype nicotinic acetylcholine receptor; PNU-120596, 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea; PAM, positive alloste

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Kinetic properties and open probability of α7 nicotinic acetylcholine receptors

Keywords: α7 nicotinic acetylcholine receptor; Choline; PNU-120596; Kinetic modelingα7 nAChR, α7 subtype nicotinic acetylcholine receptor; PNU-120596, 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea; SXT, 10–90% solution exchange time

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

The dual effect of PNU-120596 on α7 nicotinic acetylcholine receptor channels

Keywords: PNU-120596; PNU120596; α7 Nicotinic receptor; Desensitization; Channel block; Choline; Bicuculline;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines

Keywords: ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor; BA; benzylidene anabaseine; RD; residual desensitization; Ds; PAM-sensitive desensitization; Di; PAM-insensitive desensitization; PAM; positive allosteric modulator; LBD; ligand-binding domain;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه